Dr. Ferdinand Knieling

2025

• Huber, F., Schöffl, I., Müller, N., Dierl, A., Wild, E.-M., Naumann-Bartsch, N.,... Anderheiden, F. (2025). What about the heart — pediatric ALL survivors show cardiopulmonary limitations in the MinimALL Study. European Journal of Pediatrics, 184(7). https://doi.org/10.1007/s00431-025-06243-0
• Knieling, F., Brown, E.L., Eckstein, M., Thoma, O.-M., Wachter, F., Mandelbaum, H.,... Regensburger, A. (2025). Guided Multispectral Optoacoustic Tomography for 3D Imaging of the Murine Colon. Advanced Science. https://doi.org/10.1002/advs.202413434
• Knopp, M., Bender, C.J., Holzwarth, N., Li, Y., Kempf, J., Caranovic, M.,... Dreher, K.K. (2025). Shortcut learning leads to sex bias in deep learning models for photoacoustic tomography. International Journal of Computer Assisted Radiology and Surgery. https://doi.org/10.1007/s11548-025-03370-9
• Park, J., Choi, S., Knieling, F., Clingman, B., Bohndiek, S., Wang, L.V., & Kim, C. (2025). Clinical translation of photoacoustic imaging. Nature Reviews Bioengineering. https://doi.org/10.1038/s44222-024-00240-y
• Schwarz, S., Denis, L., Nedoschill, E., Bühler, A., Danko, V., Hilger, A.,... Knieling, F. (2025). Ultrasound Super-Resolution Imaging of Neonatal Cerebral Vascular Reorganization. Advanced Science, 12(12). https://doi.org/10.1002/advs.202415235

2024

• Almási-Sperling, V., Gall, C., Haney, B., Latzel, N., Knieling, F., Hilger, A.,... Rother, U. (2024). Long-Term Experience of Arterio-Venous Fistula Surgery in Children on Hemodialysis. Journal of Clinical Medicine, 13(12). https://doi.org/10.3390/jcm13123577
• Bühler, A., Brown, E.L., Nedoschill, E., Eckstein, M., Ludwig, P., Wachter, F.,... Regensburger, A. (2024). In Vivo Assessment of Deep Vascular Patterns in Murine Colitis Using Optoacoustic Mesoscopic Imaging. Advanced Science. https://doi.org/10.1002/advs.202404618
• Fagni, F., Tascilar, K., Noversa de Sousa, R., Bayat, S., Sollfrank, L., Kleyer, A.,... Simon, D. (2024). Unveiling Metabolic Similarities of Entheses in Patients with Psoriasis and Psoriatic Arthritis Using Noninvasive In Vivo Molecular Imaging: Results From a Cross-sectional Exploratory Study. Arthritis and Rheumatology, 76(9), 1387-1396. https://doi.org/10.1002/art.42917
• Hörning, A., Jüngert, J., Siebenlist, G., Knieling, F., & Regensburger, A. (2024). Ultrasound in Pediatric Inflammatory Bowel Disease—A Review of the State of the Art and Future Perspectives. Children, 11(2). https://doi.org/10.3390/children11020156
• Li, Y., Gröhl, J., Haney, B., Caranovic, M., Lorenz-Meyer, E., Papatheodorou, N.,... Rother, U. (2024). Teachability of multispectral optoacoustic tomography. Journal of Biophotonics. https://doi.org/10.1002/jbio.202400106
• Martin, S., Angolini, E., Audi, J., Bertini, E., Bruno, L.P., Coulter, J.,... Veldwijk, J. (2024). Patient preferences in genetic newborn screening for rare diseases: study protocol. BMJ Open, 14(4). https://doi.org/10.1136/bmjopen-2023-081835
• Nedoschill, E., Wagner, A.L., Danko, V., Bühler, A., Raming, R., Jüngert, J.M.,... Regensburger, A. (2024). Monitoring spinal muscular atrophy with three-dimensional optoacoustic imaging. Med, 5(5), 469-478.e3. https://doi.org/10.1016/j.medj.2024.02.010
• Noversa de Sousa, R., Tascilar, K., Corte, G., Atzinger, A., Minopoulou, I., Ohrndorf, S.,... Corte, G. (2024). Metabolic and molecular imaging in inflammatory arthritis. RMD Open, 10(1). https://doi.org/10.1136/rmdopen-2023-003880
• Regensburger, A., Eckstein, M., Wetzl, M., Raming, R., Paulus, L.-P., Bühler, A.,... Knieling, F. (2024). Multispectral optoacoustic tomography enables assessment of disease activity in paediatric inflammatory bowel disease. Photoacoustics, 35. https://doi.org/10.1016/j.pacs.2023.100578
• Regensburger, A., Wachter, F., Denis, L., Mandelbaum, H., Schey, F., Bühler, A.,... Knieling, F. (2024). Ultrasound Localization Microscopy for the Assessment of Microvascular Circulation in Ischemic Perinatal Stroke. Stroke, 55(12), e323-e325. https://doi.org/10.1161/STROKEAHA.124.048390
• Schöffl, I., Raming, R., Tratzky, J.P., Regensburger, A., Kraus, C., Wällisch, W.,... Weigelt, A. (2024). Cardiopulmonary function in paediatric post-COVID-19: a controlled clinical trial. European Journal of Pediatrics. https://doi.org/10.1007/s00431-024-05421-w
• Tan, L., Zschüntzsch, J., Meyer, S., Stobbe, A., Bruex, H., Regensburger, A.,... Knieling, F. (2024). Non-invasive optoacoustic imaging of glycogen-storage and muscle degeneration in late-onset Pompe disease. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-52143-6
• Träger, A.P., Günther, J., Raming, R., Paulus, L.-P., Lang, W., Meyer, A.,... Rother, U. (2024). Hybrid ultrasound and single wavelength optoacoustic imaging reveals muscle degeneration in peripheral artery disease. Photoacoustics, 35. https://doi.org/10.1016/j.pacs.2023.100579
• Vonk, J., Knieling, F., & Kruijff, S. (2024). Collection on clinical photoacoustic imaging. European Journal of Nuclear Medicine and Molecular Imaging. https://doi.org/10.1007/s00259-024-06780-0
• Zetzmann, K., Papatheodorou, N., Rühl, E., Yagshyyev, S., Haney, B., Moosmann, O.,... Rother, U. (2024). Detection of wound healing disorders after major amputations by measurements of the microcirculation: A prospective single-center study. SAGE Open Medicine, 12. https://doi.org/10.1177/20503121241263244

2023

• Assi, H., Cao, R., Castelino, M., Cox, B., Gilbert, F.J., Gröhl, J.,... Bohndiek, S.E. (2023). A review of a strategic roadmapping exercise to advance clinical translation of photoacoustic imaging: From current barriers to future adoption. Photoacoustics, 32. https://doi.org/10.1016/j.pacs.2023.100539
• Bühler, A., Brown, E., Paulus, L.-P., Eckstein, M., Thoma, O.-M., Oraiopoulou, M.-E.,... Regensburger, A. (2023). Transrectal Absorber Guide Raster-Scanning Optoacoustic Mesoscopy for Label-Free In Vivo Assessment of Colitis. Advanced Science. https://doi.org/10.1002/advs.202300564
• Danko, V., Jüngert, J.M., Schüssler, S., Bühler, A., Klett, D., Federle, A.,... Wagner, A. (2023). Hybrid reflected-ultrasound computed tomography versus B-mode-ultrasound for muscle scoring in spinal muscular atrophy. Journal of Neuroimaging. https://doi.org/10.1111/jon.13081
• Günther, J., Knieling, F., Träger, A.P., Lang, W., Meyer, A., Regensburger, A.,... Rother, U. (2023). Targeting Muscular Hemoglobin Content for Classification of Peripheral Arterial Disease by Noninvasive Multispectral Optoacoustic Tomography. Journal of the American College of Cardiology : Cardiovascular imaging, 16(5), 719-721. https://doi.org/10.1016/j.jcmg.2022.11.010
• Paulus, L.-P., Bühler, A., Wagner, A., Raming, R., Jüngert, J., Simon, D.,... Knieling, F. (2023). Contrast-Enhanced Multispectral Optoacoustic Tomography for Functional Assessment of the Gastrointestinal Tract. Advanced Science. https://doi.org/10.1002/advs.202302562
• Paulus, L.-P., Wagner, A., Buehler, A., Raming, R., Jüngert, J., Simon, D.,... Regensburger, A. (2023). Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow. Photoacoustics, 30. https://doi.org/10.1016/j.pacs.2023.100457
• Schnell, A., Jüngert, J.M., Klett, D., Hober, H., Kaiser, N., Ruppel, R.,... Regensburger, A. (2023). Increase of liver stiffness and altered bile acid metabolism after triple CFTR modulator initiation in children and young adults with cystic fibrosis. Liver International. https://doi.org/10.1111/liv.15544
• Späth, M., Rohde, M., Ni, D., Knieling, F., Stelzle, F., Schmidt, M.,... Hohmann, M. (2023). Author Correction: The influence of the optical properties on the determination of capillary diameters (Scientific Reports, (2022), 12, 1, (270), 10.1038/s41598-021-04359-5). Scientific Reports, 13(1). https://doi.org/10.1038/s41598-022-26996-0
• Wachter, F., Knieling, F., Raming, R., Simon, D., Wölfle, J., Hörning, A.,... Regensburger, A. (2023). Routine Surveillance of SARS-CoV-2 Serostatus in Pediatrics Allows Monitoring of Humoral Response. Microorganisms, 11(12), 2919. https://doi.org/10.3390/microorganisms11122919

2022

• Goebel, C.A., Brown, E., Fahlbusch, F., Wagner, A., Buehler, A., Raupach, T.,... Knieling, F. (2022). High-resolution label-free mapping of murine kidney vasculature by raster-scanning optoacoustic mesoscopy: an ex vivo study. Molecular and Cellular Pediatrics, 9(1). https://doi.org/10.1186/s40348-022-00144-0
• Heiß, R., Tan, L., Schmidt, S., Regensburger, A., Ewert, F., Mammadova, D.,... Knieling, F. (2022). Pulmonary Dysfunction after Pediatric COVID-19. Radiology. https://doi.org/10.1148/radiol.221250
• Knieling, F., Cesnjevar, R., Regensburger, A., Wagner, A., Purbojo, A., Dittrich, S.,... Rüffer, A. (2022). Transfontanellar Contrast-enhanced US for Intraoperative Imaging of Cerebral Perfusion during Neonatal Arterial Switch Operation. Radiology, 304(1), 164-173. https://doi.org/10.1148/radiol.212044
• Regensburger, A., Wagner, A., Danko, V., Jüngert, J.M., Federle, A., Klett, D.,... Knieling, F. (2022). Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients. Photoacoustics, 25. https://doi.org/10.1016/j.pacs.2021.100315
• Schlereth, M., Stromer, D., Breininger, K., Wagner, A., Tan, L., Maier, A., & Knieling, F. (2022). Automatic Classification of Neuromuscular Diseases in Children Using Photoacoustic Imaging. In Klaus Maier-Hein, Thomas M. Deserno, Heinz Handels, Andreas Maier, Christoph Palm, Thomas Tolxdorff (Eds.), Informatik aktuell (pp. 285-290). Heidelberg, DEU: Springer Science and Business Media Deutschland GmbH.
• Späth, M., Rohde, M., Ni, D., Knieling, F., Stelzle, F., Schmidt, M.,... Hohmann, M. (2022). The influence of the optical properties on the determination of capillary diameters. Scientific Reports, 12. https://doi.org/10.1038/s41598-021-04359-5
• Stirm, M., Fonteyne, L.M., Shashikadze, B., Stöckl, J.B., Kurome, M., Keßler, B.,... Wolf, E. (2022). Pig models for Duchenne muscular dystrophy – from disease mechanisms to validation of new diagnostic and therapeutic concepts. Neuromuscular Disorders. https://doi.org/10.1016/j.nmd.2022.04.005
• Tascilar, K., Fagni, F., Kleyer, A., Bayat, S., Heidemann, R., Steiger, F.,... Simon, D. (2022). NON-INVASIVE IN VIVO METABOLIC PROFILING OF INFLAMMATION IN JOINTS AND ENTHESES BY OPTOACOUSTIC IMAGING. In ANNALS OF THE RHEUMATIC DISEASES (pp. 1032-1032). LONDON: BMJ PUBLISHING GROUP.
• Tascilar, K., Fagni, F., Kleyer, A., Bayat, S., Heidemann, R., Steiger, F.,... Simon, D. (2022). Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography. Rheumatology. https://doi.org/10.1093/rheumatology/keac346
• Wachter, F., Regensburger, A., Peter, A.S., Knieling, F., Wagner, A., Simon, D.,... Rauh, M. (2022). Continuous monitoring of SARS-CoV-2 seroprevalence in children using residual blood samples from routine clinical chemistry. Clinical Chemistry and Laboratory Medicine. https://doi.org/10.1515/cclm-2022-0037

2021

• Aguilar, C., Regensburger, A., Knieling, F., Wagner, A., Siebenlist, G., Wölfle, J.,... Jüngert, J.M. (2021). Pediatric Buried Bumper Syndrome: Diagnostic Validity of Transabdominal Ultrasound and Artificial Intelligence. Ultraschall in der Medizin. https://doi.org/10.1055/a-1471-3039
• Regensburger, A., Brown, E., Krönke, G., Waldner, M., & Knieling, F. (2021). Optoacoustic Imaging in Inflammation. Biomedicines, 9(5). https://doi.org/10.3390/biomedicines9050483
• Rüffer, A., Knieling, F., Cesnjevar, R., Regensburger, A., Purbojo, A., Dittrich, S.,... Jüngert, J.M. (2021). Equal cerebral perfusion during extended aortic coarctation repair. European Journal of Cardio-Thoracic Surgery, 61(2), 299-306. https://doi.org/10.1093/ejcts/ezab415
• Wagner, A., Danko, V., Federle, A., Klett, D., Simon, D., Heiß, R.,... Knieling, F. (2021). Precision of handheld multispectral optoacoustic tomography for muscle imaging. Photoacoustics, 21. https://doi.org/10.1016/j.pacs.2020.100220
• Wildner, D., Heinzerling, L., Scheulen, M.E., Kämpgen, E., Schuler, G., Strobel, D.,... Knieling, F. (2021). Assessment of sorafenib induced changes in tumor perfusion of uveal melanoma metastases with dynamic contrast-enhanced ultrasound (DCE-US). Journal of Cancer Research and Clinical Oncology. https://doi.org/10.1007/s00432-021-03666-8

2020

• Knieling, F., Rüffer, A., Cesnjevar, R., Regensburger, A., Purbojo, A., Dittrich, S.,... Jüngert, J.M. (2020). Transfontanellar Contrast-Enhanced Ultrasound for Monitoring Brain Perfusion During Neonatal Heart Surgery. Circulation: Cardiovascular Imaging, 13(3), e010073-. https://doi.org/10.1161/CIRCIMAGING.119.010073
• Regensburger, A., Wagner, A., Claussen, J., Waldner, M., & Knieling, F. (2020). Shedding light on pediatric diseases: multispectral optoacoustic tomography at the doorway to clinical applications. Molecular and Cellular Pediatrics, 7(1). https://doi.org/10.1186/s40348-020-00095-4
• Regensburger, A., Wagner, A., Hanslik, G., Schuessler, S.C., Fahlbusch, F., Wölfle, J.,... Knieling, F. (2020). Ultra-high-frequency ultrasound in patients with spinal muscular atrophy: A retrospective feasibility study. Muscle & Nerve, 61(3), E18-E21. https://doi.org/10.1002/mus.26796