Our research (Medical Physics Group in the Erlangen Centre for Astroparticle Physics) is focused on measurements and detection of ionising radiation in medicine. Project examples are: development of spectroscopic x-ray pixel detectors in collaboration with CERN, development of an eye lens x-ray dosimeter for interventional radiography, radiation monitoring in FLASH radiation therapy, gamma dosimetry in collaboration with Physikalisch Technische Bundesanstalt, interferometric x-ray imaging.
- Development of spectroscopic x-ray pixel detectors in collaboration with CERN: Since many years, ECAP is member of the internaional Medipix collaborations with seat at CERN. There we develop ultra-fast, high-granularity photon-counting, spectroscopic pixel detectors for ionising radiation imaging and dose measurements. ECAP contributes with medical applications to the development of new detectors.
- Development of an eye lens x-ray dosimeter for interventional radiography: Here, we develop a small wearable electronics dosimeter to be used by radiologists in interventional radiography based on our own pixel detector Dosepix that has been developed in a collaboration between ECAP and CERN.
- Radiation monitoring in FLASH radiation therapy: Within the international UHD-pulse consortium, we will investigate the use of pixel detectors, e.g. the Dosepix, for flux monitoring/for beam control in ultra-high dose rate radiation therapy (FLASH).
- Gamma dosimetry in collaboration with Physikalisch Technische Bundesanstalt: Together with PTB in Braunschweig, we investigate the use of photon counting pixel detectors for measurements of equivalent doses in pulsed radiation fields and for high-flux spectroscopy.
- Interferometric x-ray imaging: Here, we use and develop Talbot-Lau x-ray interferometers (3 microstructured gratings in the beam path) to measure images of the phase shift of x-ray waves through the object and to measure the granularity of the object on the micrometer scale.
Optische Intensitätsinterferometrie mit den H.E.S.S. Gammastrahlungsteleskopen
(Third Party Funds Single)Term: 1. January 2020 - 31. December 2022
Funding source: DFG-Einzelförderung / Sachbeihilfe (EIN-SBH)
The aim of this project is to develop a system for optical intensity interferometry for the H.E.S.S gamma-ray telescopes in Namibia and to perform high-angular resolution measurement of stars in the V and R bands. The proposed project consists of three modules: a) development of the light-detection and electronics chain, b) development of the mechanical and optical struture and c) development of data analysis tools. We aim to demonstrate the feasibility of the full chain developed in this proposal to measure the stellar diameters of bright stars on timescales of a few hours (detect the signal at a projected 5-m baseline within minutes).
- Behrens, R., Hufschmidt, P., Roth, J., Akstaller, B., Hupe, O., Haag, D.,... Michel, T. (2022). Radiation measurements and simulations at the PHELIX laser facility, GSI. Journal of Instrumentation, 17(5). https://dx.doi.org/10.1088/1748-0221/17/05/P05033
- Karl, S., Zmija, A., Richter, S., Vogel, N., Malyshev, D., Zink, A.,... Funk, S. (2022). Comparing different approaches for stellar intensity interferometry. Monthly Notices of the Royal Astronomical Society, 512(2), 1722-1729. https://dx.doi.org/10.1093/mnras/stac489
- Wolf, A., Akstaller, B., Cipiccia, S., Flenner, S., Hagemann, J., Ludwig, V.,... Funk, S. (2022). Single-exposure X-ray phase imaging microscopy with a grating interferometer. Journal of Synchrotron Radiation, 29, 794-806. https://dx.doi.org/10.1107/S160057752200193X
- Zmija, A., Vogel, N., Anton, G., Malyshev, D., Michel, T., Zink, A., & Funk, S. (2022). Optical intensity interferometry lab tests in preparation of stellar diameter measurements at IACTs at GHz photon rates. Monthly Notices of the Royal Astronomical Society, 509(3), 3113-3118. https://dx.doi.org/10.1093/mnras/stab3058
- Haag, D., Schmidt, S., Hufschmidt, P., Eberle, F., Michel, T., Anton, G.,... Wong, W. (2021). Personal Dosimetry in Continuous Photon Radiation Fields with the Dosepix Detector. IEEE Transactions on Nuclear Science. https://dx.doi.org/10.1109/TNS.2021.3068832
- Stiegler, T., Sangiorgio, S., Brodsky, J.P., Heffner, M., Kharusi, S.A., Anton, G.,... Ziegler, T. (2021). Event reconstruction in a liquid xenon Time Projection Chamber with an optically-open field cage. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1000. https://dx.doi.org/10.1016/j.nima.2021.165239
- Al Kharusi, S., Anton, G., Badhrees, I., Barbeau, P.S., Beck, D., Belov, V.,... Ziegler, T. (2020). Measurement of the Spectral Shape of the beta-Decay of Xe-137 to the Ground State of Cs-137 in EXO-200 and Comparison with Theory. Physical Review Letters, 124(23). https://dx.doi.org/10.1103/PhysRevLett.124.232502
- Anton, G., Badhrees, I., Barbeau, P.S., Beck, D., Belov, V., Bhatta, T.,... Ziegler, T. (2020). Measurement of the scintillation and ionization response of liquid xenon at MeV energies in the EXO-200 experiment. Physical Review C - Nuclear Physics, 101(6). https://dx.doi.org/10.1103/PhysRevC.101.065501
- Emons, J., Fasching, P., Wunderle, M., Heindl, F., Rieger, J., Horn, F.,... Jud, S. (2020). Assessment of the additional clinical potential of X-ray dark-field imaging for breast cancer in a preclinical setup. Therapeutic Advances in Medical Oncology, 12. https://dx.doi.org/10.1177/1758835920957932
- Emons, J., Fasching, P., Wunderle, M., Heindl, F., Rieger, J., Horn, F.,... Jud, S.M. (2020). Assessment of the additional clinical potential of X-ray dark-field imaging for breast cancer in a preclinical setup. In GEBURTSHILFE UND FRAUENHEILKUNDE (pp. E111-E111). STUTTGART: GEORG THIEME VERLAG KG.
- Ludwig, V., Akstaller, B., Schuster, M., Seifert, M., Wolf, A., Michel, T., & Anton, G. (2020). A phase-sampling method for an X-ray Talbot-Lau scanner with continuous grating movement. Journal of Instrumentation, 15(1). https://dx.doi.org/10.1088/1748-0221/15/01/P01010
- Lv, P., Cao, G.F., Wen, L.J., Kharusi, S.A., Anton, G., Arnquist, I.J.,... Ziegler, T. (2020). Reflectance of Silicon Photomultipliers at Vacuum Ultraviolet Wavelengths. IEEE Transactions on Nuclear Science, 67(12), 2501-2510. https://dx.doi.org/10.1109/TNS.2020.3035172
- Nakarmi, P., Ostrovskiy, I., Soma, A.K., Retière, F., Kharusi, S.A., Alfaris, M.,... Ziegler, T. (2020). Reflectivity and PDE of VUV4 Hamamatsu SiPMs in liquid xenon. Journal of Instrumentation, 15(1). https://dx.doi.org/10.1088/1748-0221/15/01/P01019
- Njoya, O., Tsang, T., Tarka, M., Fairbank, W., Kumar, K.S., Rao, T.,... Ziegler, T. (2020). Measurements of electron transport in liquid and gas Xenon using a laser-driven photocathode. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 972. https://dx.doi.org/10.1016/j.nima.2020.163965
- Rauch, T., Rieger, J., Pelzer, G., Horn, F., Erber, R., Wunderle, M.,... Anton, G. (2020). Discrimination analysis of breast calcifications using x-ray dark-field radiography. Medical Physics. https://dx.doi.org/10.1002/mp.14043
- Seifert, M., Weule, M., Cipiccia, S., Flenner, S., Hagemann, J., Ludwig, V.,... Akstaller, B. (2020). Evaluation of the Weighted Mean X-ray Energy for an Imaging System Via Propagation-Based Phase-Contrast Imaging. Journal of Imaging, 6(7). https://dx.doi.org/10.3390/jimaging6070063
- Zmija, A., Deiml, P., Malyshev, D., Zink, A., Anton, G., Michel, T., & Funk, S. (2020). LED as laboratory test source for astronomical intensity interferometry. Optics Express, 28(4), 5248-5256. https://dx.doi.org/10.1364/OE.28.005248