Prof. Alessandro Del Vecchio

2024

• Goodlich, B.I., Pearcey, G.E., Del Vecchio, A., Horan, S.A., & Kavanagh, J.J. (2024). Antagonism of 5-HT2 receptors attenuates self-sustained firing of human motor units. The Journal of Physiology. https://dx.doi.org/10.1113/JP285867
• Möck, S., & Del Vecchio, A. (2024). Investigation of motor unit behavior in exercise and sports physiology: challenges and perspectives. Applied Physiology, Nutrition, and Metabolism, 49(4), 547-553. https://dx.doi.org/10.1139/apnm-2023-0354
• Rahimi, F., Badamchizadeh, M.A., Ghaemi, S., & Del Vecchio, A. (2024). Simultaneous Estimation of Digit Tip Forces and Hand Postures in a Simulated Real-life Condition with High-density Electromyography and Deep Learning. IEEE Journal of Biomedical and Health Informatics, 1-8. https://dx.doi.org/10.1109/JBHI.2024.3350239
• Simpetru, R., Cnejevici, V., Farina, D., & Del Vecchio, A. (2024). Influence of spatio-temporal filtering on hand kinematics estimation from high-density EMG signals. Journal of Neural Engineering, 21, 026014. https://dx.doi.org/10.1088/1741-2552/ad3498
• Valli, G., Sarto, F., Casolo, A., Del Vecchio, A., Franchi, M.V., Narici, M.V., & De Vito, G. (2024). Lower limb suspension induces threshold-specific alterations of motor units properties that are reversed by active recovery. Journal of Sport and Health Science, 13(2), 264-276. https://dx.doi.org/10.1016/j.jshs.2023.06.004
• Weinman, L.E., Del Vecchio, A., Mazzo, M.R., & Enoka, R.M. (2024). Motor unit modes in the calf muscles during a submaximal isometric contraction are changed by brief stretches. The Journal of Physiology, 602(7), 1385-1404. https://dx.doi.org/10.1113/JP285437

2023

• Alix-Fages, C., Jiménez-Martínez, P., Souza de Oliveira, D., Möck, S., Balsalobre-Fernández, C., & Del Vecchio, A. (2023). Mental fatigue impairs physical performance but not the neural drive to the muscle: a preliminary analysis. European Journal of Applied Physiology. https://dx.doi.org/10.1007/s00421-023-05189-1
• Baker, A.M., Maffitt, N.J., Del Vecchio, A., McKeating, K.M., Baker, M.R., Baker, S.N., & Soteropoulos, D.S. (2023). Neural dysregulation in post-COVID fatigue. Brain Communications, 5(3). https://dx.doi.org/10.1093/braincomms/fcad122
• Borutta, M., Köhn, J., Souza de Oliveira, D., Del Vecchio, A., Engelhorn, T., Schwab, S.,... Kinfe, T.M. (2023). The Impact of Burst Motor Cortex Stimulation on Cardiovascular Autonomic Modulation in Chronic Pain: A Feasibility Study for a New Approach to Objectively Monitor Therapeutic Effects. Pain and Therapy. https://doi.org/10.1007/s40122-023-00541-x
• Borzuola, R., Nuccio, S., Scalia, M., Parrella, M., Del Vecchio, A., Bazzucchi, I.,... Macaluso, A. (2023). Adjustments in the motor unit discharge behavior following neuromuscular electrical stimulation compared to voluntary contractions. Frontiers in Physiology, 14. https://dx.doi.org/10.3389/fphys.2023.1212453
• Casolo, A., Maeo, S., Balshaw, T.G., Lanza, M.B., Martin, N.R.W., Nuccio, S.,... Del Vecchio, A. (2023). Non-invasive estimation of muscle fibre size from high-density electromyography. The Journal of Physiology. https://doi.org/10.1113/JP284170
• Del Vecchio, A. (2023). Neuromechanics of the Rate of Force Development. Exercise and Sport Sciences Reviews, 51(1), 34-42. https://dx.doi.org/10.1249/JES.0000000000000306
• Del Vecchio, A., Marconi Germer, C., Kinfe, T.M., Nuccio, S., Hug, F., Eskofier, B.,... Enoka, R.M. (2023). The Forces Generated by Agonist Muscles during Isometric Contractions Arise from Motor Unit Synergies. The Journal of Neuroscience, 43(16), 2860-2873. https://doi.org/10.1523/JNEUROSCI.1265-22.2023
• Dideriksen, J., & Del Vecchio, A. (2023). Adaptations in motor unit properties underlying changes in recruitment, rate coding, and maximum force. Journal of Neurophysiology, 129(1), 235-246. https://dx.doi.org/10.1152/jn.00222.2022
• Goodlich, B.I., Del Vecchio, A., Horan, S.A., & Kavanagh, J.J. (2023). Blockade of 5-HT2 receptors suppresses motor unit firing and estimates of persistent inward currents during voluntary muscle contraction in humans. The Journal of Physiology. https://dx.doi.org/10.1113/JP284164
• Goodlich, B.I., Del Vecchio, A., & Kavanagh, J.J. (2023). Motor unit tracking using blind source separation filters and waveform cross-correlations: reliability under physiological and pharmacological conditions. Journal of Applied Physiology, 135(2), 362-374. https://dx.doi.org/10.1152/japplphysiol.00271.2023
• Lecce, E., Nuccio, S., Del Vecchio, A., Conti, A., Nicolo, A., Sacchetti, M.,... Bazzucchi, I. (2023). The acute effects of whole-body vibration on motor unit recruitment and discharge properties. Frontiers in Physiology, 14. https://dx.doi.org/10.3389/fphys.2023.1124242
• Lecce, E., Nuccio, S., Del Vecchio, A., Conti, A., Nicolò, A., Sacchetti, M.,... Bazzucchi, I. (2023). Sensorimotor integration is affected by acute whole-body vibration: a coherence study. Frontiers in Physiology, 14. https://dx.doi.org/10.3389/fphys.2023.1266085
• Mayer, K., Del Vecchio, A., Eskofier, B., & Farina, D. (2023). Unsupervised neural decoding of signals recorded by thin-film electrode arrays implanted in muscles using autoencoding with a physiologically derived optimisation criterion. Biomedical Signal Processing and Control, 86. https://doi.org/10.1016/j.bspc.2023.105178
• Qassim, H., Zhao, Y., Ströbel, A., Regensburger, M., Buchfelder, M., Souza de Oliveira, D.,... Kinfe, T.M. (2023). Deep Brain Stimulation for Chronic Facial Pain: An Individual Participant Data (IPD) Meta-Analysis. Brain Sciences, 13(3). https://doi.org/10.3390/brainsci13030492
• Simpetru, R., März, M., & Del Vecchio, A. (2023). Proportional and Simultaneous Real-Time Control of the Full Human Hand From High-Density Electromyography. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 31, 3118-3131. https://dx.doi.org/10.1109/TNSRE.2023.3295060
• Škarabot, J., Folland, J.P., Forsyth, J., Vazoukis, A., Holobar, A., & Del Vecchio, A. (2023). Motor Unit Discharge Characteristics and Conduction Velocity of the Vastii Muscles in Long-Term Resistance-Trained Men. Medicine and science in sports and exercise , 55(5), 824-836. https://dx.doi.org/10.1249/MSS.0000000000003105

2022

• Alix-Fages, C., Del Vecchio, A., Baz-Valle, E., Santos-Concejero, J., & Balsalobre-Fernandez, C. (2022). The role of the neural stimulus in regulating skeletal muscle hypertrophy. European Journal of Applied Physiology. https://doi.org/10.1007/s00421-022-04906-6
• Bräcklein, M., Barsakcioglu, D.Y., Del Vecchio, A., Ibáñez, J., & Farina, D. (2022). Reading and Modulating Cortical β Bursts from Motor Unit Spiking Activity. The Journal of Neuroscience, 42(17), 3611-3621. https://dx.doi.org/10.1523/JNEUROSCI.1885-21.2022
• Cakici, A., Oßwald, M., Souza de Oliveira, D., Braun, D., Simpetru, R., Kinfe, T.M.,... Del Vecchio, A. (2022). A Generalized Framework for the Study of Spinal Motor Neurons Controlling the Human Hand During Dynamic Movements. In Proceedings of the 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022 (pp. 4115-4118). Scottish Event Campus, Glasgow, GB: Institute of Electrical and Electronics Engineers Inc..
• Cakici, A.L., Oßwald, M., Souza de Oliveira, D., Braun, D., Simpetru, R.C., Kinfe, T.M.,... Del Vecchio, A. (2022). A Generalized Framework for the Study of Spinal Motor Neurons Controlling the Human Hand During Dynamic Movements. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 4115-4118). Glasgow, GBR: Institute of Electrical and Electronics Engineers Inc..
• Del Vecchio, A., Casolo, A., Dideriksen, J.L., Aagaard, P., Felici, F., Falla, D., & Farina, D. (2022). Lack of increased rate of force development after strength training is explained by specific neural, not muscular, motor unit adaptations. Journal of Applied Physiology, 132(1), 84-94. https://doi.org/10.1152/japplphysiol.00218.2021
• Del Vecchio, A., Jones, R.H., Schofield, I.S., Kinfe, T.M., Ibáñez, J., Farina, D., & Baker, S.N. (2022). Interfacing Motor Units in Nonhuman Primates Identifies a Principal Neural Component for Force Control Constrained by the Size Principle. The Journal of Neuroscience, 42(39), 7386-7399. https://doi.org/10.1523/JNEUROSCI.0649-22.2022
• Hug, F., Avrillon, S., Sarcher, A., Del Vecchio, A., & Farina, D. (2022). Correlation networks of spinal motor neurons that innervate lower limb muscles during a multi-joint isometric task. The Journal of Physiology. https://dx.doi.org/10.1113/JP283040
• Ibanez, J., Zicher, B., Brown, K.E., Rocchi, L., Casolo, A., Del Vecchio, A.,... Farina, D. (2022). Standard intensities of transcranial alternating current stimulation over the motor cortex do not entrain corticospinal inputs to motor neurons. The Journal of Physiology. https://dx.doi.org/10.1113/JP282983
• Kinfe, T.M., Del Vecchio, A., Nüssel, M., Zhao, Y., Stadlbauer, A., & Buchfelder, M. (2022). Deep brain stimulation and stereotactic-assisted brain graft injection targeting fronto-striatal circuits for Huntington's disease: an update. Expert review of neurotherapeutics. https://doi.org/10.1080/14737175.2022.2091988
• Nüssel, M., Zhao, Y., Knorr, C., Regensburger, M., Stadlbauer, A., Buchfelder, M.,... Kinfe, T.M. (2022). Deep Brain Stimulation, Stereotactic Radiosurgery and High-Intensity Focused Ultrasound Targeting the Limbic Pain Matrix: A Comprehensive Review. Pain and Therapy. https://doi.org/10.1007/s40122-022-00381-1
• Ritzmann, R., Del Vecchio, A., Baudry, S., Place, N., Gollhofer, A., Narici, M., & Centner, C. (2022). Editorial: Neuromechanics in Movement and Disease With Physiological and Pathophysiological Implications: From Fundamental Experiments to Bio-Inspired Technologies. Frontiers in Physiology, 13. https://dx.doi.org/10.3389/fphys.2022.895968
• Simpetru, R., Oßwald, M., Braun, D., Souza de Oliveira, D., Cakici, A., & Del Vecchio, A. (2022). Accurate Continuous Prediction of 14 Degrees of Freedom of the Hand from Myoelectrical Signals through Convolutive Deep Learning. In Proceedings of the 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022 (pp. 702-706). Scottish Event Campus, Glasgow, UK, GB: Institute of Electrical and Electronics Engineers Inc..
• Simpetru, R.C., Oßwald, M., Braun, D., Souza de Oliveira, D., Cakici, A.L., & Del Vecchio, A. (2022). Accurate Continuous Prediction of 14 Degrees of Freedom of the Hand from Myoelectrical Signals through Convolutive Deep Learning. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 702-706). Glasgow, GBR: Institute of Electrical and Electronics Engineers Inc..
• Souza de Oliveira, D., Casolo, A., Balshaw, T.G., Maeo, S., Lanza, M.B., Martin, N.R.W.,... Del Vecchio, A. (2022). Neural decoding from surface high-density EMG signals: influence of anatomy and synchronization on the number of identified motor units. Journal of Neural Engineering, 19(4). https://doi.org/10.1088/1741-2552/ac823d
• Ubeda, A., Costa-Garcia, A., Torricelli, D., Vujaklija, I., & Del Vecchio, A. (2022). Editorial: Neuromechanical Biomarkers in Robot-Assisted Motor Rehabilitation. Frontiers in Neurorobotics, 15. https://doi.org/10.3389/fnbot.2021.831113
• Walter, J., Roßmanith, P., Souza de Oliveira, D., Reitelshofer, S., Del Vecchio, A., & Franke, J. (2022). Proportional Control of a Soft Cable-Driven Exoskeleton via a Myoelectrical Interface Enables Force-Controlled Finger Motions. In International Conference on Biomedical Robotics and Biomechatronics (BioRob). Seoul, KR: Seoul.
• Škarabot, J., Folland, J.P., Holobar, A., Baker, S.N., & Del Vecchio, A. (2022). Startling stimuli increase maximal motor unit discharge rate and rate of force development in humans. Journal of Neurophysiology, 128(3), 455-469. https://dx.doi.org/10.1152/jn.00115.2022

2021

• Avrillon, S., Del Vecchio, A., Farina, D., Pons, J.L., Vogel, C., Umehara, J., & Hug, F. (2021). Individual differences in the neural strategies to control the lateral and medial head of the quadriceps during a mechanically constrained task. Journal of Applied Physiology, 130(1), 269-281. https://doi.org/10.1152/japplphysiol.00653.2020
• Casolo, A., Del Vecchio, A., Balshaw, T.G., Maeo, S., Lanza, M.B., Felici, F.,... Farina, D. (2021). Behavior of motor units during submaximal isometric contractions in chronically strength-trained individuals. Journal of Applied Physiology, 131(5), 1584-1598. https://doi.org/10.1152/japplphysiol.00192.2021
• Del Vecchio, A., Beckerle, P., & Castellini, C. (2021). Peripheral Neuroergonomics – An Elegant Way to Improve Human-Robot Interaction? Frontiers in Neurorobotics, 15. https://doi.org/10.3389/fnbot.2021.691508
• Germer, C.M., Farina, D., Elias, L.A., Nuccio, S., Hug, F., & Del Vecchio, A. (2021). Surface EMG cross talk quantified at the motor unit population level for muscles of the hand, thigh, and calf. Journal of Applied Physiology, 131(2), 808-820. https://doi.org/10.1152/japplphysiol.01041.2020
• Hug, F., Avrillon, S., Del Vecchio, A., Casolo, A., Ibanez, J., Nuccio, S.,... Farina, D. (2021). Analysis of motor unit spike trains estimated from high-density surface electromyography is highly reliable across operators. Journal of Electromyography and Kinesiology, 58. https://doi.org/10.1016/j.jelekin.2021.102548
• Hug, F., Del Vecchio, A., Avrillon, S., Farina, D., & Tucker, K. (2021). Muscles from the same muscle group do not necessarily share common drive: evidence from the human triceps surae. Journal of Applied Physiology, 130(2), 342-354. https://doi.org/10.1152/JAPPLPHYSIOL.00635.2020
• Ibanez, J., Del Vecchio, A., Rothwell, J.C., Baker, S.N., & Farina, D. (2021). Only the fastest corticospinal fibers contribute to beta corticomuscular coherence. Journal of Neuroscience, JN-RM-2908-20. https://doi.org/10.1523/JNEUROSCI.2908-20.2021
• Nuccio, S., Del Vecchio, A., Casolo, A., Labanca, L., Rocchi, J.E., Felici, F.,... Sbriccoli, P. (2021). Deficit in knee extension strength following anterior cruciate ligament reconstruction is explained by a reduced neural drive to the vasti muscles. The Journal of Physiology. https://doi.org/10.1113/JP282014
• Schrader, B., Schrader, J., Vaske, B., Elsaesser, A., Haller, H., Del Vecchio, A.,... Lueders, S. (2021). Football beats hypertension: results of the 3F (Fit&Fun with Football) study. Journal of Hypertension, 39(11), 2290-2296. https://doi.org/10.1097/HJH.0000000000002935
• Ting, J., Del Vecchio, A., Verma, N., Sarma, D., Annetta, N., Collinger, J.,... Weber, D.J. (2021). Detecting and decoding spiking activity from sample populations of single motor neurons using wearable sensors. In SPIE BiOS (Eds.), Proceedings Volume 11663, Integrated Sensors for Biological and Neural Sensing.
• Ting, J.E., Del Vecchio, A., Sarma, D., Verma, N., Colachis, S.C., Annetta, N.,... Weber, D.J. (2021). Sensing and decoding the neural drive to paralyzed muscles during attempted movements of a person with tetraplegia using a sleeve array. Journal of Neurophysiology, 126(6), 2104-2118. https://doi.org/10.1152/jn.00220.2021

2020

• Casolo, A., Farina, D., Falla, D., Bazzucchi, I., Felici, F., & Del Vecchio, A. (2020). Strength Training Increases Conduction Velocity of High-Threshold Motor Units. Medicine and science in sports and exercise , 52(4), 955-967. https://dx.doi.org/10.1249/MSS.0000000000002196
• Casolo, A., Nuccio, S., Bazzucchi, I., Felici, F., & Del Vecchio, A. (2020). Reproducibility of muscle fibre conduction velocity during linearly increasing force contractions. Journal of Electromyography and Kinesiology, 53. https://dx.doi.org/10.1016/j.jelekin.2020.102439
• Del Vecchio, A., & Farina, D. (2020). Interfacing the neural output of the spinal cord: Robust and reliable longitudinal identification of motor neurons in humans. Journal of Neural Engineering, 17(1). https://dx.doi.org/10.1088/1741-2552/ab4d05
• Del Vecchio, A., Holobar, A., Falla, D., Felici, F., Enoka, R.M., & Farina, D. (2020). Tutorial: Analysis of motor unit discharge characteristics from high-density surface EMG signals. Journal of Electromyography and Kinesiology, 53. https://dx.doi.org/10.1016/j.jelekin.2020.102426
• Del Vecchio, A., Negro, F., Holobar, A., Casolo, A., Folland, J.P., Felici, F., & Farina, D. (2020). Direct translation of findings in isolated animal preparations to in vivo human motoneuron behaviour is challenging. The Journal of Physiology, 598(5), 1111-1112. https://dx.doi.org/10.1113/JP279384
• Del Vecchio, A., Sylos-Labini, F., Mondi, V., Paolillo, P., Ivanenko, Y., Lacquaniti, F., & Farina, D. (2020). Spinal motoneurons of the human newborn are highly synchronized during leg movements. Science Advances, 6, eabc3916. https://doi.org/10.1126/sciadv.abc3916
• Dideriksen, J.L., Del Vecchio, A., & Farina, D. (2020). Neural and muscular determinants of maximal rate of force development. Journal of Neurophysiology, 123(1), 149-157. https://dx.doi.org/10.1152/jn.00330.2019
• Felici, F., & Del Vecchio, A. (2020). Surface Electromyography: What Limits Its Use in Exercise and Sport Physiology? Frontiers in Neurology, 11. https://doi.org/10.3389/fneur.2020.578504
• Germer, C.M., Del Vecchio, A., Negro, F., Farina, D., & Elias, L.A. (2020). Neurophysiological correlates of force control improvement induced by sinusoidal vibrotactile stimulation. Journal of Neural Engineering, 17(1). https://dx.doi.org/10.1088/1741-2552/ab5e08
• Nuccio, S., Del Vecchio, A., Casolo, A., Labanca, L., Rocchi, J.E., Felici, F.,... Sbriccoli, P. (2020). Muscle fiber conduction velocity in the vastus lateralis and medialis muscles of soccer players after ACL reconstruction. Scandinavian journal of medicine & science in sports, 30(10), 1976-1984. https://dx.doi.org/10.1111/sms.13748
• Skarabot, J., Brownstein, C.G., Casolo, A., Del Vecchio, A., & Ansdell, P. (2020). The knowns and unknowns of neural adaptations to resistance training. European Journal of Applied Physiology. https://doi.org/10.1007/s00421-020-04567-3
• Tanzarella, S., Muceli, S., Del Vecchio, A., Casolo, A., & Farina, D. (2020). Non-invasive analysis of motor neurons controlling the intrinsic and extrinsic muscles of the hand. Journal of Neural Engineering, 17(4). https://dx.doi.org/10.1088/1741-2552/aba6db