Prof. Dr. Claudio Castellini
Chair of Assistive Intelligent Robotics / Department Artificial Intelligence in Biomedical Engineering (AIBE)

Prof. Dr. Claudio Castellini
Chair of Assistive Intelligent Robotics / Department Artificial Intelligence in Biomedical Engineering (AIBE)
I am a researcher in medical robotics, focussing on rehabilitation and assistive robotics, human-machine interfaces and interaction and applied machine learning. Currently, I lead the Assistive Intelligent Robotics Group at FAU and keep a part-time position as senior researcher at the Institute of Robotics and Mechatronics of the German Aerospace Center. My main interest lies in the proper design and translation of integrated rehabilitation and assistive solutions for patients of musculoskeletal degenerative conditions, sufferers of limb absence and elderly people needing semi-autonomous care.
Research Projects
- Investigating advanced sensors and sensing modalities for intent detection
- Investigating techniques to provide sensory feedback to users of rehabilitation and assistive devices
- Strategies to shape the interaction and user experience
- Theoretical machine learning and psychology – two sides of the same coin!
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AutoAssist: Interaktive Künstliche Intelligenz und Einschätzung des Muskeltonus
(Third Party Funds Group – Sub project)
Overall project: Artificial Intelligence for Assist-as-needed Rehabilitation Therapies
Project leader:
Term: 1. February 2025 - 31. January 2028
Acronym: AutoAssist
Funding source: BMFTR / Verbundprojekt
2026
- Andreas, D., Dwivedi, A., Castellini, C., & Beckerle, P. (2026). From muscles to motion: the role of sensor layout and physiological factors in hand motion decoding. Scientific Reports, 16. https://doi.org/10.1038/s41598-026-59979-6
- De Bartolo, D., De Pasquale, P., Russo, M., Berger, D.J., Maselli, A., Borzelli, D.,... d'Avella, A. (2026). Usability, Acceptability, and Feasibility of a Personalized Adaptive Mirror Therapy for Upper-Limb Poststroke Rehabilitation Using Immersive Virtual Reality and Myoelectric Control: Single-Arm Pre-Post Study. JMIR Rehabilitation and Assistive Technologies. https://doi.org/10.2196/81894
- Domenico, D.D., Egle, F., Marinelli, A., Canepa, M., Gruppioni, E., Boccardo, N.,... Castellini, C. (2026). Co-Adaptive Velocity and Position Control of 3-DoFs Prosthesis via Incremental Learning. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 34, 856-867. https://doi.org/10.1109/TNSRE.2026.3657400
- Egle, F., Kleinbeck, C., Herzer, L., Beckerle, P., Roth, D., & Castellini, C. (2026). Reliability in Focus: Trust, Agency, Ownership, and Gaze Behaviour in a VR Prosthesis Simulator. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 1-1. https://doi.org/10.1109/TNSRE.2026.3676703
- Scheidl, M.-A., Schuh, K., Sierotowicz, M., Betsch, M., & Castellini, C. (2026). EMG-controlled knee orthosis lowers effort in sit-to-stand. Frontiers in Robotics and AI, 12. https://doi.org/10.3389/frobt.2025.1732294
- Scheidl, M.-A., Thürauf, S., Castellini, C., & Behrendt, J. (2026). Pass-On Control: Personalized Assistive Online Control for a Wrist Exosuit. In 2026 IEEE/SICE International Symposium on System Integration, SII 2026 (pp. 1047-1053). Cancun, MX: Institute of Electrical and Electronics Engineers Inc..
2025
- Abbass, Y., Miranda Montenegro, S., Egle, F., Saleh, M., Valle, M., & Castellini, C. (2025). A Case Study: FMG-based Gesture Recognition using High-Density Piezoelectric Electronic Skin and Machine Learning. IEEE Sensors Letters, 1-4. https://doi.org/10.1109/LSENS.2025.3624027
- Anam, K., Ardhiansyah, D.D., Sasono, M.A.H., Imron, A.M.N., Rizal, N.A., Ramadhan, M.E.,... Sumardi, . (2025). Myoelectric grip force prediction using deep learning for hand robot. IAES International Journal of Artificial Intelligence (IJ-AI), 14(4), 3228-3240. https://doi.org/10.11591/ijai.v14.i4.pp3228-3240
- Anam, K., Sudrajat, A., Rizal, N.A., Intyanto, G.W., Muldayani, W., Negara, M.A.P.,... Castellini, C. (2025). Evaluation of LSTM for predicting grip strength using electromyography: a comparison of setups and methods. Neural Computing & Applications. https://doi.org/10.1007/s00521-025-11337-9
- Andreas, D., Werner, D., Hou, Z., Dwivedi, A., Castellini, C., & Beckerle, P. (2025). A database of multimodal myography and hand kinematics during realistic daily life activities. Scientific Data, 12. https://doi.org/10.1038/s41597-025-05852-6
- Campbell, E., Egle, F., Oßwald, M., Côté-Allard, U., Pilarski, P.M., Boccardo, N.,... Scheme, E. (2025). (Un)supervised (Co)adaptation via Incremental Learning for Myoelectric Control: Motivation, Review, and Future Directions. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 1-1. https://doi.org/10.1109/TNSRE.2025.3602397
- Canepa, M., Marucchi, L., Boccardo, N., Marinelli, A., Di Domenico, D., Gandolla, M.,... Castellini, C. (2025). Towards a Real-Time, Interactive, Incremental Learning Algorithm for Prosthetic Myocontrol. In 2025 International Conference On Rehabilitation Robotics (ICORR) (pp. 95-100). Chicago, IL, US: IEEE Computer Society.
- Iozzo, P., De Bartolo, D., Russo, M., Berger, D.J., Maselli, A., Borzelli, D.,... d'Avella, A. (2025). User-centered development of a personalized adaptive mirror therapy for upper-limb post-stroke rehabilitation using virtual reality and myoelectric control. Frontiers in Bioengineering and Biotechnology, 13. https://doi.org/10.3389/fbioe.2025.1655416
- Scheidl, M.-A., Akarsu, İ.B., Mehrkens, F., Czierlinski, B., & Castellini, C. (2025). An Impedance-Controlled Knee Orthosis for Assisted Sit-to-Stand. In Jose L. Pons, Jesus Tornero, Metin Akay (Eds.), Converging Clinical and Engineering Research on Neurorehabilitation V. Proceedings of the 6th International Conference on Neurorehabilitation (ICNR 2024), November 5–8, 2024, La Granja, Spain - Volume 1 (pp. 279-283). La Granja, ES: Cham: Springer.
- Scheidl, M.-A., Braun, H., Akarsu, I.B., & Castellini, C. (2025). Impedance-Controlled Knee Orthosis: Transitional Movements and their Effect on Knee Kinematics and Muscular Activity. In IEEE International Conference on Rehabilitation Robotics (pp. 1185-1190). Chicago, IL, US: IEEE Computer Society.
- Scheidl, M.-A., Braun, H., Behrendt, J., & Castellini, C. (2025). Exploring Position, Velocity, and Torque Control via Minimal sEMG Calibration for Robotic Ankle Prostheses. In Proceedings of the 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2025. Institute of Electrical and Electronics Engineers Inc..
- Scheidl, M.-A., Wunder, P., Czierlinski, B., & Castellini, C. (2025). Preliminary assessment of an open-source leg prosthesis based upon the OSL 2.0. In 2025 IEEE/SICE International Symposium on System Integration (SII) (pp. 115-120). München, DE: New York City: IEEE.
- Schulz, A., Egle, F., Oßwald, M., Del Vecchio, A., & Castellini, C. (2025). Towards Unsupervised Incremental and Proportional Myocontrol Based on Higher-Density Surface Electromyography. In 2025 International Conference On Rehabilitation Robotics (ICORR) (pp. 1106-1111). Chicago, IL, US: IEEE Computer Society.
- Sierotowicz, M., Brusamento, D., Missiroli, F., Bornmann, J., Gonzalez-Vargas, J., Masia, L., & Castellini, C. (2025). Wearable Assistive Robotics and Its Interaction with Muscular Recruitment Strategies. In (pp. 139-143). Springer Science and Business Media Deutschland GmbH.
- Sierotowicz, M., Castellini, C., & Anam, K. (2025). Force Myography Shows Higher Correlation to Force Output Compared to ARV EMG Features. In IEEE International Conference on Rehabilitation Robotics (pp. 642-647). Chicago, IL, USA: IEEE Computer Society.
- Sierotowicz, M., Castellini, C., & Anam, K. (2025). Force Myography Shows Higher Correlation to Force Output Compared to Average Rectified Value Electromyography Features. In (pp. 627-631). Springer Science and Business Media Deutschland GmbH.
- Thürauf, S., Mehrkens, F., Castellini, C., & Sierotowicz, M. (2025). Back to the Cartesian: Pilot Study for Assessing Human Stiffness in 3D Cartesian Space by Transforming from Muscle Space in a Peg-In-Hole Scenario for Tele-Impedance. In Christian Ott, Henny Admoni, Sven Behnke, Stjepan Bogdan, Aude Bolopion, Youngjin Choi, Fanny Ficuciello, Nicholas Gans, Clement Gosselin, Kensuke Harada, Erdal Kayacan, H. Jin Kim, Stefan Leutenegger, Zhe Liu, Perla Maiolino, Lino Marques, Takamitsu Matsubara, Anastasia Mavromatti, Mark Minor, Jason O'Kane, Hae Won Park, Hae-Won Park, Ioannis Rekleitis, Federico Renda, Elisa Ricci, Laurel D. Riek, Lorenzo Sabattini, Shaojie Shen, Yu Sun, Pierre-Brice Wieber, Katsu Yamane, Jingjin Yu (Eds.), Proceedings - IEEE International Conference on Robotics and Automation (pp. 5906-5913). Atlanta, GA, US: Institute of Electrical and Electronics Engineers Inc..
2024
- Castañeda, T.S., Connan, M., Capsi-Morales, P., Beckerle, P., Castellini, C., & Piazza, C. (2024). Correction to: Experimental evaluation of the impact of sEMG interfaces in enhancing embodiment of virtual myoelectric prostheses (Journal of NeuroEngineering and Rehabilitation, (2024), 21, 1, (57), 10.1186/s12984-024-01352-7). Journal of neuroEngineering and rehabilitation, 21(1). https://doi.org/10.1186/s12984-024-01368-z
- Castañeda, T.S., Connan, M., Capsi-Morales, P., Beckerle, P., Castellini, C., & Piazza, C. (2024). Experimental evaluation of the impact of sEMG interfaces in enhancing embodiment of virtual myoelectric prostheses. Journal of neuroEngineering and rehabilitation, 21(1). https://doi.org/10.1186/s12984-024-01352-7
- Ouyang, J., Egle, F., Igney, C., Mutzke, T., Dahmani, C., Castellini, C., & Thürauf, S. (2024). C-arm unleashed: Intuitive inter-operative positioning of C-arms using wearable gesture detection. In Proceedings of the BioRob 2024. Heidelberg, DE.
- Souza de Oliveira, D., Ponfick, M., Braun, D., Oßwald, M., Sierotowicz, M., Chatterjee, S.,... Del Vecchio, A. (2024). A direct spinal cord–computer interface enables the control of the paralysed hand in spinal cord injury. Brain, 147(10), 3583-3595. https://doi.org/10.1093/brain/awae088
- Yang, X., Castellini, C., Farina, D., & Liu, H. (2024). Ultrasound as a Neurorobotic Interface: A Review. IEEE Transactions on Systems, Man, and Cybernetics: Systems, 54(6), 3534-3546. https://doi.org/10.1109/TSMC.2024.3358960
2023
- Egle, F., Di Domenico, D., Marinelli, A., Boccardo, N., Canepa, M., Laffranchi, M.,... Castellini, C. (2023). Preliminary Assessment of Two Simultaneous and Proportional Myocontrol Methods for 3-DoFs Prostheses Using Incremental Learning. In Proceedings of the 2023 International Conference on Rehabilitation Robotics (ICORR). Singapur, SG: IEEE.
- Gigli, A., Gijsberts, A., Nowak, M., Vujaklija, I., & Castellini, C. (2023). Progressive unsupervised control of myoelectric upper limbs. Journal of Neural Engineering. https://doi.org/10.1088/1741-2552/ad0754
- Nowak, M., Bongers, R.M., van der Sluis, C.K., Albu-Schäffer, A., & Castellini, C. (2023). Simultaneous assessment and training of an upper-limb amputee using incremental machine-learning-based myocontrol: a single-case experimental design. Journal of neuroEngineering and rehabilitation, 20(1), 39-. https://doi.org/10.1186/s12984-023-01171-2
- Nowak, M., Vujaklija, I., Sturma, A., Castellini, C., & Farina, D. (2023). Simultaneous and Proportional Real-Time Myocontrol of Up to Three Degrees of Freedom of the Wrist and Hand. IEEE Transactions on Biomedical Engineering, 70(2), 459-469. https://doi.org/10.1109/TBME.2022.3194104
- Sierotowicz, M., & Castellini, C. (2023). Omnidirectional endpoint force control through functional electrical stimulation. Biomedical Physics and Engineering Express, 9(6). https://doi.org/10.1088/2057-1976/acf04b
- Sierotowicz, M., & Castellini, C. (2023). Robot-Inspired Human Impedance Control Through Functional Electrical Stimulation. In Proceedings of the 2023 International Conference on Rehabilitation Robotics (ICORR). Singapur, SG: IEEE.
- Sierotowicz, M., Scheidl, M.-A., & Castellini, C. (2023). Adaptive Filter for Biosignal-Driven Force Controls Preserves Predictive Powers of sEMG. In Proceedings of the 2023 International Conference on Rehabilitation Robotics (ICORR). Singapur, SG: IEEE.
2022
- Al-Timemy, A.H., Castellini, C., Escudero, J., Khushaba, R., & Muceli, S. (2022). Current Trends in Deep Learning for Movement Analysis and Prosthesis Control. Frontiers in Neuroscience, 16. https://doi.org/10.3389/fnins.2022.889202
- Beckerle, P., Castellini, C., Lenggenhager, B., & Dosen, S. (2022). Embodiment and Co-Adaptation through Human-Machine Interfaces: at the border of Robotics, Neuroscience and Psychology. Frontiers in Neurorobotics, 16. https://doi.org/10.3389/fnbot.2022.871785
- Castellini, C. (2022). Peripheral Nervous System Interfaces: Invasive or Non-invasive? Frontiers in Neurorobotics, 16. https://doi.org/10.3389/fnbot.2022.846866
- Gigli, A., Gijsberts, A., & Castellini, C. (2022). Unsupervised Myocontrol of a Virtual Hand Based on a Coadaptive Abstract Motor Mapping. In IEEE International Conference on Rehabilitation Robotics. Rotterdam, NL: IEEE Computer Society.
- Sierotowicz, M., Brusamento, D., Schirrmeister, B., Connan, M., Bornmann, J., Gonzalez-Vargas, J., & Castellini, C. (2022). Unobtrusive, natural support control of an adaptive industrial exoskeleton using force myography. Frontiers in Robotics and AI, 9. https://doi.org/10.3389/frobt.2022.919370
- Sierotowicz, M., Lotti, N., Nell, L., Missiroli, F., Alicea, R., Zhang, X.,... Castellini, C. (2022). EMG-driven Machine Learning Control of a Soft Glove for Grasping Assistance and Rehabilitation. IEEE Robotics and Automation Letters, 7(2), 1566-1573. https://doi.org/10.1109/LRA.2021.3140055
- Sierotowicz, M., Lotti, N., Rupp, R., Masia, L., & Castellini, C. (2022). A Comprehensive Framework for the Modelling of Cartesian Force Output in Human Limbs. In IEEE International Conference on Rehabilitation Robotics. Rotterdam, NL: IEEE Computer Society.
2021
- Del Vecchio, A., Beckerle, P., & Castellini, C. (2021). Peripheral Neuroergonomics – An Elegant Way to Improve Human-Robot Interaction? Frontiers in Neurorobotics, 15. https://doi.org/10.3389/fnbot.2021.691508
2020
- Connan, M., Koiva, R., & Castellini, C. (2020). Online Natural Myocontrol of Combined Hand and Wrist Actions Using Tactile Myography and the Biomechanics of Grasping. Frontiers in Neurorobotics, 14. https://doi.org/10.3389/fnbot.2020.00011
- Gigli, A., Brusamento, D., Meattini, R., Melchiorri, C., & Castellini, C. (2020). Feedback-aided data acquisition improves myoelectric control of a prosthetic hand. Journal of Neural Engineering, 17(5). https://doi.org/10.1088/1741-2552/abbed0
- Gigli, A., Gijsberts, A., & Castellini, C. (2020). The Merits of Dynamic Data Acquisition for Realistic Myocontrol. Frontiers in Bioengineering and Biotechnology, 8. https://doi.org/10.3389/fbioe.2020.00361
- Nowak, M., Eiband, T., Ramirez, E.R., & Castellini, C. (2020). Action interference in simultaneous and proportional myocontrol: Comparing force- A nd electromyography. Journal of Neural Engineering, 17(2). https://doi.org/10.1088/1741-2552/ab7b1e
- Sharma, K., Stulp, F., Van Den Broek, E.L., & Castellini, C. (2020). Continuous, Real-Time Emotion Annotation: A Novel Joystick-Based Analysis Framework. IEEE Transactions on Affective Computing, 11(1), 78-84. https://doi.org/10.1109/TAFFC.2017.2772882
- Sierotowicz, M., Connan, M., & Castellini, C. (2020). Human-in-the-loop assessment of an ultralight, low-cost body posture tracking device. Sensors.
- Sierotowicz, M., Connan, M., & Castellini, C. (2020). Human-in-the-loop assessment of an ultralight, low-cost body posture tracking device. Sensors, 20(3). https://doi.org/10.3390/s20030890