Molecular understanding of the basic processes of tumour development and progression, furthermore the translation of the results into clinical practice.

Research projects

  • Cancer
  • Cell Biology
  • Biomedical Science
  • Methods:  Immunohistochemie, Protein Analyse, PCR, Cell Culture, Cloning
  • Growth factor and matrix-induced modulation of the tumor cells and the tumor micro-milieu
  • Effects of Cold atmospheric plasma on cancer cells
  • Impact of cellular dormancy or senescence on tumor cells and clinical outcome

  • Modulation of oncogene-induced senescence by cell-matrix adhesion

    (FAU Funds)

    Term: 16. March 2020 - 15. September 2022

    Oncogene-induced senescence (OIS) was recently introduced as a strong tumor suppressive mechanism seen e.g. in development of nevi out of melanocytes after BRAF mutation. Tumor cells like melanoma obviously can overcome these limiting mechanisms by further changes, however the molecular mechanisms leading to and overcoming OIS are just being started to be understood. We aim to understand the role of cell adhesion processes and mechanotransduction in induction and overcoming OIS.

  • Ultrasensitive marker-free biomolecular THz-detection for tumor related analytics: PCR-free sensitivity, biomolecular extension and biological relevance

    (Third Party Funds Group – Sub project)

    Overall project: SPP 1857: Elektromagnetische Sensoren für Life Sciences (ESSENCE)
    Term: 1. January 2015 - 30. September 2022
    Funding source: DFG / Schwerpunktprogramm (SPP)

2021

2020

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