Molecular understanding of the basic processes of tumour development and progression, furthermore the translation of the results into clinical practice.

Research projects

  • Cancer
  • Cell Biology
  • Biomedical Science
  • Methods:  Immunohistochemie, Protein Analyse, PCR, Cell Culture, Cloning
  • Growth factor and matrix-induced modulation of the tumor cells and the tumor micro-milieu
  • Effects of Cold atmospheric plasma on cancer cells
  • Impact of cellular dormancy or senescence on tumor cells and clinical outcome

Current projects

  • MGluR7 in the cochlea: molecular composition and protective function at ribbon synapses of inner hair cells

    (FAU Funds)

    Term: 1. September 2021 - 31. August 2022
  • Modulation of oncogene-induced senescence by cell-matrix adhesion

    (FAU Funds)

    Term: 16. March 2020 - 15. September 2022
    Oncogene-induced senescence (OIS) was recently introduced as a strong tumor suppressive mechanism seen e.g. in development of nevi out of melanocytes after BRAF mutation. Tumor cells like melanoma obviously can overcome these limiting mechanisms by further changes, however the molecular mechanisms leading to and overcoming OIS are just being started to be understood. We aim to understand the role of cell adhesion processes and mechanotransduction in induction and overcoming OIS.
  • Ultrasensitive marker-free biomolecular THz-detection for tumor related analytics: PCR-free sensitivity, biomolecular extension and biological relevance

    (Third Party Funds Group – Sub project)

    Overall project: SPP 1857: Elektromagnetische Sensoren für Life Sciences (ESSENCE)
    Term: 1. January 2015 - 30. September 2022
    Funding source: DFG / Schwerpunktprogramm (SPP)

Recent publications

2022

2021

2020

Related Research Fields

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