Research projects
Physiology and electrophysiology of the healthy and diseased retina and its significance for visual perception.
Research in human subjects (healthy subjects and well-described patient groups with retinal disorders) and in animals (healthy animals; animal models for human diseases and genetically modified animals).
Interaktionen der fotorezeptor-generierten Signale im Elektroretinogramm von Mäusen Function and dysfunction of rod- and cone-driven pathways: novel approaches for measuring treatment effects Eine neue Sicht der postrezeptoralen Signalverarbeitung in retino-genikulärer Sehbahnen beim Menschen Retina 2.0. Image acquisition from retina to sensors.
Decoding central defects in dystrophinopathies: from diagnostic to remediation Artificial Intelligence for Diagnosing Retinal Diseases
Recent publications
2021
Aher, A., Horn, F., Huchzermeyer, C., Lämmer, R., & Kremers, J. (2021). Responses of postreceptoral pathways elicited by L- And M-cone isolating ON- And OFF-electroretinograms in glaucoma patients . Investigative Ophthalmology & Visual Science , 62 (9). https://dx.doi.org/10.1167/iovs.62.9.14
Aher, A., Horn, F., Huchzermeyer, C., Lämmer, R., & Kremers, J. (2021). Spatial properties of L- and M-cone driven incremental (on-) and decremental (off-) electroretinograms: normal subjects Vs. glaucoma patients . In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
Assis, J.B., Brasil, A., Loureiro, T.M.G., da Silva, V.G.R., Herculano, A.M., Ventura, D.F.,... Souza, G.S. (2021). Pseudorandom full-field electroretinograms reflect different light adaptation mechanisms . Documenta Ophthalmologica . https://dx.doi.org/10.1007/s10633-021-09822-2
Barboni, M.T.S., Dias, S.L., Silva, L.A., Damico, F.M., Vidal, K.S., Costa, M.F.,... Ventura, D.F. (2021). Correlations between dark-adapted rod threshold elevations and erg response deficits in duchenne muscular dystrophy . Investigative Ophthalmology & Visual Science , 62 (4). https://dx.doi.org/10.1167/iovs.62.4.29
Barboni, M.T.S., Liber, A.M.P., Joachimsthaler, A., Saoudi, A., Goyenvalle, A., Rendon, A.,... Vaillend, C. (2021). Altered visual processing in the mdx52 mouse model of Duchenne muscular dystrophy . Neurobiology of Disease , 152 . https://dx.doi.org/10.1016/j.nbd.2021.105288
Fars, J., Huchzermeyer, C., & Kremers, J. (2021). Psychometric curves in retinitis pigmentosa patients . In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
Huchzermeyer, C., Fars, J., & Kremers, J. (2021). Relationship between temporal L-coneflicker sensitivity and established clinical parameters in Stargardt's disease . In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
Huchzermeyer, C., Horn, F., Lämmer, R., Mardin, C., & Kremers, J. (2021). Summation of Temporal L-Cone- and M-Cone-Contrast in the Magno- and Parvocellular Retino-Geniculate Systems in Glaucoma . Investigative Ophthalmology & Visual Science , 62 (6), 17-. https://dx.doi.org/10.1167/iovs.62.6.17
Joachimsthaler, A., Stallwitz, N., & Kremers, J. (2021). Combining temporal white noise stimulation and silent substitution technique: wnERGs driven by single photoreceptor types in LIAIS mice . In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
Kremers, J., Aher, A., Parry, N.R., Patel, N.B., & Frishman, L.J. (2021). Comparison of macaque and human L- and M-cone driven electroretinograms . Experimental Eye Research , 206 . https://dx.doi.org/10.1016/j.exer.2021.108556
Ryl, M., Urbasik, A., Gierke, K., Babai, N., Joachimsthaler, A., Feigenspan, A.,... Brandstätter, J.H. (2021). Genetic disruption of bassoon in two mutant mouse lines causes divergent retinal phenotypes . The FASEB Journal , 35 (5), e21520-. https://dx.doi.org/10.1096/fj.202001962R
Vidal, K.S., Aher, A., Ventura, D.F., & Kremers, J. (2021). The spatial distribution of ERGs reflecting luminance and L-/M-cone-opponent signals . Documenta Ophthalmologica . https://dx.doi.org/10.1007/s10633-020-09807-7
2020
Barboni, M.T.S., Dias, S., Silva, L., Damico, F.M., Vidal, K.S., Costa, M.F.,... Ventura, D.F. (2020). Dark adapted cone/rod thresholds and ERGs in Duchenne muscular dystrophy . In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . ONLINE: ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
Fars, J., Kremers, J., & Huchzermeyer, C. (2020). Discriminating anomalous trichromacy and cone degeneration in retinitis pigmentosa patients . In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . ONLINE: ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
Gierke, K., von Wittgenstein, J., Hemmerlein, M., Atorf, J., Joachimsthaler, A., Kremers, J.,... Brandstätter, J.H. (2020). Heterogeneous presynaptic distribution of munc13 isoforms at retinal synapses and identification of an unconventional bipolar cell type with dual expression of munc13 isoforms: A study using munc13-exfp knock-in mice . International Journal of Molecular Sciences , 21 (21), 1-20. https://dx.doi.org/10.3390/ijms21217848
Huchzermeyer, C., Fars, J., & Kremers, J. (2020). Photoreceptor-specific loss of perifoveal temporal contrassensitivity in retinitis pigmentosa . Translational Vision Science & Technology , 9 (6), 1-15. https://dx.doi.org/10.1167/TVST.9.6.27
Huchzermeyer, C., Fars, J., Lorenz, B., & Kremers, J. (2020). Patterns of photoreceptor-specific temporal contrast sensitivity losses in patients with different phenotypic variants of retinitis pigmentosa . In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . ONLINE: ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC.
Huchzermeyer, C., Fars, J., Stöhr, H., & Kremers, J. (2020). Neue Techniken zur Quantifizierung des Farbsinns bei Störungen der Zapfenfunktion . Ophthalmologe . https://dx.doi.org/10.1007/s00347-020-01119-0
Kremers, J., McKeefry, D.J., Murray, I.J., & Parry, N.R. (2020). Developments in non-invasive visual electrophysiology . Vision research , 174 , 50-56. https://dx.doi.org/10.1016/j.visres.2020.05.003
Nittmann, M.G., Aher, A., Kremers, J., & Tzekov, R. (2020). Relationship between stimulus size and different components of the electroretinogram (ERG) elicited by flashed stimuli . Documenta Ophthalmologica . https://dx.doi.org/10.1007/s10633-020-09797-6
Salgueiro Barboni, M.T., Vaillend, C., Joachimsthaler, A., Passos Liber, A.M., Khabou, H., Roux, M.J.,... Kremers, J. (2020). Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71 . Investigative Ophthalmology & Visual Science , 61 (2). https://dx.doi.org/10.1167/iovs.61.2.11
Wise, E.N., Foster, M.L., Kremers, J., & Mowat, F.M. (2020). A modified silent substitution electroretinography protocol to separate photoreceptor subclass function in lightly sedated dogs . Veterinary Ophthalmology . https://dx.doi.org/10.1111/vop.12847
Yan, X., Atorf, J., Ramos, D., Thiele, F., Weber, S., Dalke, C.,... Graw, J. (2020). Mutation in Bmpr1b Leads to Optic Disc Coloboma and Ventral Retinal Gliosis in Mice . Investigative Ophthalmology & Visual Science , 61 (2). https://dx.doi.org/10.1167/iovs.61.2.44
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2021
2020
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