Advanced imaging in gastroenterology.
Research projects
molecular endoscopy optoacoustics near infraved imaging
Current projects Current projects
Recent publications Recent publications
2023
Atreya, R., & Neurath, M. (2023). The sphingosine-1-phosphate receptor agonist etrasimod in ulcerative colitis . Lancet . https://dx.doi.org/10.1016/S0140-6736(23)00228-3
Baronetto, A., Graf, L., Fischer, S., Neurath, M., & Amft, O. (2023). Segment-Based Spotting of Bowel Sounds Using Pretrained Models in Continuous Data Streams . IEEE Journal of Biomedical and Health Informatics , 1-12. https://dx.doi.org/10.1109/JBHI.2023.3269910
Bühler, A., Brown, E., Paulus, L.-P., Eckstein, M., Thoma, O.-M., Oraiopoulou, M.-E.,... Regensburger, A. (2023). Transrectal Absorber Guide Raster-Scanning Optoacoustic Mesoscopy for Label-Free In Vivo Assessment of Colitis . Advanced Science . https://dx.doi.org/10.1002/advs.202300564
Danko, V., Jüngert, J.M., Schüssler, S., Bühler, A., Klett, D., Federle, A.,... Wagner, A. (2023). Hybrid reflected-ultrasound computed tomography versus B-mode-ultrasound for muscle scoring in spinal muscular atrophy . Journal of Neuroimaging . https://dx.doi.org/10.1111/jon.13081
Dedden, M., Wiendl, M., Müller, T., Neurath, M., & Zundler, S. (2023). Manual cell selection in single cell transcriptomics using scSELpy supports the analysis of immune cell subsets . Frontiers in Immunology , 14 . https://dx.doi.org/10.3389/fimmu.2023.1027346
Günther, J., Knieling, F., Träger, A.P., Lang, W., Meyer, A., Regensburger, A.,... Rother, U. (2023). Targeting Muscular Hemoglobin Content for Classification of Peripheral Arterial Disease by Noninvasive Multispectral Optoacoustic Tomography . Journal of the American College of Cardiology : Cardiovascular imaging , 16 (5), 719-721. https://dx.doi.org/10.1016/j.jcmg.2022.11.010
Heidbreder, K., Sommer, K., Wiendl, M., Müller, T., Atreya, I., Hildner, K.,... Zundler, S. (2023). Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine . Frontiers in Immunology , 13 . https://dx.doi.org/10.3389/fimmu.2022.1040775
Jefremow, A., & Neurath, M. (2023). Novel Small Molecules in IBD: Current State and Future Perspectives . Cells , 12 (13). https://dx.doi.org/10.3390/cells12131730
Koop, K., Enderle, K., Hillmann, M., Ruspeckhofer, L., Vieth, M., Sturm, G.,... Neufert, C. (2023). Interleukin 36 receptor-inducible matrix metalloproteinase 13 mediates intestinal fibrosis . Frontiers in Immunology , 14 . https://dx.doi.org/10.3389/fimmu.2023.1163198
Müller, T., Liu, L., Czerwinski, T., Wiesinger, M., Dedden, M., Paap, E.-M.,... Bosch-Voskens, C. (2023). Increased Motility and Suppression of Ex Vivo–Expanded Regulatory T Cells Designed for Adoptive Transfer Therapy in Ulcerative Colitis . Cellular and Molecular Gastroenterology and Hepatology . https://dx.doi.org/10.1016/j.jcmgh.2023.04.002
Neurath, M., & Vieth, M. (2023). Different levels of healing in inflammatory bowel diseases: mucosal, histological, transmural, barrier and complete healing . Gut . https://dx.doi.org/10.1136/gutjnl-2023-329964
Paulus, L.-P., Wagner, A., Buehler, A., Raming, R., Jüngert, J., Simon, D.,... Regensburger, A. (2023). Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow . Photoacoustics , 30 . https://dx.doi.org/10.1016/j.pacs.2023.100457
Rath, T., Atreya, R., Bodenschatz, J., Uter, W., Geppert, C.-I., Vitali, F.,... Neurath, M. (2023). Intestinal Barrier Healing Is Superior to Endoscopic and Histologic Remission for Predicting Major Adverse Outcomes in Inflammatory Bowel Disease: The Prospective ERIca Trial . Gastroenterology , 164 (2), 241-255. https://dx.doi.org/10.1053/j.gastro.2022.10.014
Reljic, D., Frenk, F., Herrmann, H.J., Neurath, M., & Zopf, Y. (2023). Maximum Heart Rate- and Lactate Threshold-Based Low-Volume High-Intensity Interval Training Prescriptions Provide Similar Health Benefits in Metabolic Syndrome Patients . Healthcare , 11 (5). https://dx.doi.org/10.3390/healthcare11050711
Schnell, A., Jüngert, J.M., Klett, D., Hober, H., Kaiser, N., Ruppel, R.,... Regensburger, A. (2023). Increase of liver stiffness and altered bile acid metabolism after triple CFTR modulator initiation in children and young adults with cystic fibrosis . Liver International . https://dx.doi.org/10.1111/liv.15544
Sommer, K., Heidbreder, K., Kreiß, L., Dedden, M., Paap, E.-M., Wiendl, M.,... Zundler, S. (2023). Anti-beta 7 integrin treatment impedes the recruitment on non-classical monocytes to the gut and delays macrophage-mediated intestinal wound healing . Clinical and Translational Medicine , 13 (4). https://dx.doi.org/10.1002/ctm2.1233
Soteriou, D., Kubankova, M., Schweitzer, C., Lopez Posadas, R., Pradhan, R., Thoma, O.-M.,... Guck, J. (2023). Rapid single-cell physical phenotyping of mechanically dissociated tissue biopsies . Nature Biomedical Engineering . https://dx.doi.org/10.1038/s41551-023-01015-3
Verstockt, B., Salas, A., Sands, B.E., Abraham, C., Leibovitzh, H., Neurath, M., & Vande Casteele, N. (2023). IL-12 and IL-23 pathway inhibition in inflammatory bowel disease . Nature Reviews Gastroenterology & Hepatology . https://dx.doi.org/10.1038/s41575-023-00768-1
Waldner, M., & Neurath, M. (2023). TGFβ and the Tumor Microenvironment in Colorectal Cancer . Cells , 12 (8). https://dx.doi.org/10.3390/cells12081139
Wittner, L., Wagener, L., Wiese, J.J., Stolzer, I., Krug, S.M., Naschberger, E.,... Günther, C. (2023). Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing . International Journal of Molecular Sciences , 24 (8). https://dx.doi.org/10.3390/ijms24087402
Zundler, S., Vitali, F., Kharboutli, S., Völkl, S., Polifka, I., Mackensen, A.,... Mougiakakos, D. (2023). Case Report: IBD-like colitis following CAR T cell therapy for diffuse large B cell lymphoma . Frontiers in Oncology , 13 . https://dx.doi.org/10.3389/fonc.2023.1149450
2022
Atreya, I., & Neurath, M. (2022). How the Tumor Micromilieu Modulates the Recruitment and Activation of Colorectal Cancer-Infiltrating Lymphocytes . Biomedicines , 10 (11). https://dx.doi.org/10.3390/biomedicines10112940
Atreya, R., Bojarski, C., Kühl, A.A., Trajanoski, Z., Neurath, M., & Siegmund, B. (2022). Ileal and colonic Crohn's disease: Does location makes a difference in therapy efficacy? Current Research in Pharmacology and Drug Discovery , 3 . https://dx.doi.org/10.1016/j.crphar.2022.100097
Atreya, R., & Neurath, M. (2022). Deciphering Novel Mechanistic and Pharmacokinetic Effects of Tofacitinib in Intestinal Inflammation: Expect the Unexpected . Cellular and Molecular Gastroenterology and Hepatology , 13 (2), 672-673. https://dx.doi.org/10.1016/j.jcmgh.2021.10.003
Atreya, R., & Neurath, M. (2022). IL-23 Blockade in Anti-TNF Refractory IBD: From Mechanisms to Clinical Reality . Journal of Crohns & Colitis , 16 (SUPPL 2). https://dx.doi.org/10.1093/ecco-jcc/jjac007
Atreya, R., & Neurath, M. (2022). Induction of microRNA-124 as a novel therapeutic concept in ulcerative colitis . Lancet Gastroenterology and Hepatology , 7 (11), 977-978. https://dx.doi.org/10.1016/S2468-1253(22)00249-7
Atreya, R., & Neurath, M. (2022). Inflammatory bowel diseases - therapy update 2022 Chronisch-entzündliche Darmerkrankungen . Deutsche Medizinische Wochenschrift , 147 (6), 295-300. https://dx.doi.org/10.1055/a-1585-4026
Becker, E., Schweda, A., Ullrich, K., Voskens, C., Atreya, R., Müller, T.,... Zundler, S. (2022). Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets . Clinical and Translational Gastroenterology , 13 (6), e00494-. https://dx.doi.org/10.14309/ctg.0000000000000494
Besendorf, L., Müller, T., Geppert, C.-I., Schneider, I., Mühl, L., Atreya, I.,... Zundler, S. (2022). Vedolizumab blocks alpha 4 beta 7 integrin-mediated T cell adhesion to MAdCAM-1 in microscopic colitis . Therapeutic Advances in Gastroenterology , 15 . https://dx.doi.org/10.1177/17562848221098899
Beyna, T., Moreels, T., Arvanitakis, M., Pioche, M., Saurin, J.-C., May, A.,... Neuhaus, H. (2022). Motorized spiral enteroscopy: Results of an international multicenter prospective observational clinical study in patients with normal and altered gastrointestinal anatomy . Endoscopy . https://dx.doi.org/10.1055/a-1831-6215
Casadei-Gardini, A., Rimini, M., Kudo, M., Shimose, S., Tada, T., Suda, G.,... Cascinu, S. (2022). Real Life Study of Lenvatinib Therapy for Hepatocellular Carcinoma: RELEVANT Study . Liver Cancer , 11 (6), 527-539. https://dx.doi.org/10.1159/000525145
Denk, D., Petrocelli, V., Conche, C., Drachsler, M., Ziegler, P.K., Braun, A.,... Greten, F.R. (2022). Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy . Immunity , 55 (11), 2059-2073.e8. https://dx.doi.org/10.1016/j.immuni.2022.09.014
Dieterich, W., Schuster, C., Gundel, P., Scherf, K.A., Pronin, D., Geisslitz, S.,... Zopf, Y. (2022). Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS . Nutrients , 14 (20). https://dx.doi.org/10.3390/nu14204257
Dubinsky, M.C., Magro, F., Steinwurz, F., Hudesman, D.P., Kinnucan, J.A., Ungaro, R.C.,... Regueiro, M. (2022). Association of C-reactive Protein and Partial Mayo Score With Response to Tofacitinib Induction Therapy: Results From the Ulcerative Colitis Clinical Program . Inflammatory Bowel Diseases . https://dx.doi.org/10.1093/ibd/izac061
Düll, M., Karlen, V., Vetter, M., Dietrich, P., Kupfer, J., Neurath, M., & Kremer, A. (2022). Chronic pruritus represents a major burden in non-cholestatic hepatobiliary disorders . In JOURNAL OF HEPATOLOGY (pp. S163-S163). AMSTERDAM: ELSEVIER.
Gabel, M., Knauß, A., Fischer, D., Neurath, M., & Weigmann, B. (2022). Surface Design Options in Polymer- and Lipid-Based siRNA Nanoparticles Using Antibodies . International Journal of Molecular Sciences , 23 (22). https://dx.doi.org/10.3390/ijms232213929
Ganzleben, I., Klett, D., Hartz, W., Götzfried, L., Vitali, F., Neurath, M., & Waldner, M. (2022). Multispectral optoacoustic tomography for the non-invasive identification of patients with severe anemia in vivo . Photoacoustics , 28 . https://dx.doi.org/10.1016/j.pacs.2022.100414
Gerlach, K., Popp, V., Wirtz, S., Al-Saifi, R., Gonzalez Acera, M., Atreya, R.,... Neurath, M. (2022). PU.1-driven Th9 Cells Promote Colorectal Cancer in Experimental Colitis Models Through Il-6 Effects in Intestinal Epithelial Cells . Journal of Crohns & Colitis . https://dx.doi.org/10.1093/ecco-jcc/jjac097
Gerner, M., Vuillerme, N., Aubourg, T., Messner, E.M., Terhorst, Y., Hörmann, V.,... Orlemann, T. (2022). Review and Analysis of German Mobile Apps for Inflammatory Bowel Disease Management Using the Mobile Application Rating Scale: Systematic Search in App Stores and Content Analysis . JMIR mHealth and uHealth , 10 (5). https://dx.doi.org/10.2196/31102
Gámez Belmonte, M.d.l.R., Mahapatro, M., Erkert, L., Gonzalez Acera, M., Naschberger, E., Yu, Y.,... Becker, C. (2022). Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling . Gut . https://dx.doi.org/10.1136/gutjnl-2022-327323
Gähler, A., Trufa, D., Chiriac, M.-T., Tausche, P., Hohenberger, K., Brunst, A.-K.,... Neurath-Finotto, S. (2022). Glucose-Restricted Diet Regulates the Tumor Immune Microenvironment and Prevents Tumor Growth in Lung Adenocarcinoma . Frontiers in Oncology , 12 . https://dx.doi.org/10.3389/fonc.2022.873293
Günther, C., Winner, B., Neurath, M., & Stappenbeck, T.S. (2022). Organoids in gastrointestinal diseases: from experimental models to clinical translation . Gut . https://dx.doi.org/10.1136/gutjnl-2021-326560
Heichler, C., Schmied, A., Enderle, K., Scheibe, K., Murawska, M., Schmid, B.,... Neufert, C. (2022). Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis-Associated Cancer in Mice . Cancers , 14 (6). https://dx.doi.org/10.3390/cancers14061472
Heim, L., Yang, Z., Tausche, P., Hohenberger, K., Chiriac, M.-T., Kölle, J.,... Neurath-Finotto, S. (2022). IL-9 Producing Tumor-Infiltrating Lymphocytes and Treg Subsets Drive Immune Escape of Tumor Cells in Non-Small Cell Lung Cancer . Frontiers in Immunology , 13 . https://dx.doi.org/10.3389/fimmu.2022.859738
Hohmann, M., Ganzleben, I., Grünberg, A., Menezes, J.G., Klämpfl, F., Lengenfelder, B.,... Schmidt, M. (2022). In vivo multi spectral colonoscopy in mice . Scientific Reports , 12 (1). https://dx.doi.org/10.1038/s41598-022-12794-1
Klett, D., Jesper, D., Vitali, F., Federle, A., Atreya, R., Strobel, D.,... Waldner, M. (2022). Non-invasive assessment of intestinal inflammatory activity in Ulcerative Colitis by Multispectral Optoacoustic Tomography (MSOT) . In JOURNAL OF CROHNS & COLITIS (pp. I062-I062). OXFORD: OXFORD UNIV PRESS.
Kliem, T., Strobel, D., Heinke, F., Pavel, M.E., Neurath, M., & Neufert, C. (2022). Case report: persistent fever after SARS-CoV-2 infection Fallbericht: Persistierendes Fieber nach SARS-CoV-2-Infektion . Internist . https://dx.doi.org/10.1007/s00108-022-01315-x
Knauß, A., Gabel, M., Neurath, M., & Weigmann, B. (2022). The Memory T Cell “Communication Web” in Context with Gastrointestinal Disorders—How Memory T Cells Affect Their Surroundings and How They Are Influenced by It . Cells , 11 (18). https://dx.doi.org/10.3390/cells11182780
Kreiß, L., Ganzleben, I., Mühlberg, A., Ritter, P., Schneidereit, D., Becker, C.,... Waldner, M. (2022). Label-free analysis of inflammatory tissue remodeling in murine lung tissue based on multiphoton microscopy, Raman spectroscopy and machine learning . Journal of Biophotonics . https://dx.doi.org/10.1002/jbio.202200073
Kreiß, L., Thoma, O.-M., Lemire, S., Lechner, K., Carlé, B.-E., Dilipkumar, A.,... Waldner, M. (2022). Label-Free Characterization and Quantification of Mucosal Inflammation in Common Murine Colitis Models With Multiphoton Imaging . Inflammatory Bowel Diseases . https://dx.doi.org/10.1093/ibd/izac114
Lanfer, J., Winner, B., Kaindl, J., Krumm, L., Acera, M.G., Neurath, M.,... Krach, F. (2022). Efficient and Easy Conversion of Human iPSCs into Functional Induced Microglia-like Cells . International Journal of Molecular Sciences , 23 (9). https://dx.doi.org/10.3390/ijms23094526
Lechner, K., Zeeshan, M., Noack, M., Ali, H., Neurath, M., & Weigmann, B. (2022). Small but powerful: will nanoparticles be the future state‐of‐the‐art therapy for IBD? Expert Opinion on Drug Delivery . https://dx.doi.org/10.1080/17425247.2022.2043847
Lemire, S., Thoma, O.-M., Kreiß, L., Völkl, S., Friedrich, O., Neurath, M.,... Waldner, M. (2022). Natural NADH and FAD Autofluorescence as Label-Free Biomarkers for Discriminating Subtypes and Functional States of Immune Cells . International Journal of Molecular Sciences , 23 (4). https://dx.doi.org/10.3390/ijms23042338
Leppkes, M., Lindemann, A., Goesswein, S., Paulus, S., Roth, D., Hartung, A.,... Neurath, M. (2022). Neutrophils prevent rectal bleeding in Ulcerative Colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis . In JOURNAL OF CROHNS & COLITIS (pp. I178-I179). OXFORD: OXFORD UNIV PRESS.
Leppkes, M., & Neurath, M. (2022). Rear Window—What Can the Gut Tell Us About Long-COVID? Gastroenterology , 163 (2), 376-378. https://dx.doi.org/10.1053/j.gastro.2022.05.044
Martínez Sánchez, L.d.C., Phuong Anh Ngo, ., Pradhan, R., Becker, L.S., Böhringer, D., Soteriou, D.,... Lopez Posadas, R. (2022). Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation . Gut . https://dx.doi.org/10.1136/gutjnl-2021-325520
Matthe, D., Thoma, O.-M., Sperka, T., Neurath, M., & Waldner, M. (2022). Telomerase deficiency reflects age-associated changes in CD4+T cells . Immunity & Ageing , 19 (1). https://dx.doi.org/10.1186/s12979-022-00273-0
Monteleone, G., Stolfi, C., Marafini, I., Atreya, R., & Neurath, M. (2022). Smad7 Antisense Oligonucleotide-Based Therapy in Crohn's Disease: Is it Time to Re-Evaluate? Molecular Diagnosis & Therapy . https://dx.doi.org/10.1007/s40291-022-00606-1
Neurath, M. (2022). Targeting cytokines in inflammatory bowel disease. Science Translational Medicine , 14 (675). https://dx.doi.org/10.1126/scitranslmed.abq4473
Neurath, M., & Vieth, M. (2022). Is non-invasive Cytosponge the holy grail for Barrett's neoplasia? The Lancet. Oncology , 23 (2), 190-191. https://dx.doi.org/10.1016/S1470-2045(21)00755-5
Ngo, P.A., Neurath, M., & Lopez Posadas, R. (2022). Impact of Epithelial Cell Shedding on Intestinal Homeostasis . International Journal of Molecular Sciences , 23 (8). https://dx.doi.org/10.3390/ijms23084160
Regensburger, A., Wagner, A., Danko, V., Jüngert, J.M., Federle, A., Klett, D.,... Knieling, F. (2022). Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients . Photoacoustics , 25 . https://dx.doi.org/10.1016/j.pacs.2021.100315
Reljic, D., Dieterich, W., Herrmann, H.J., Neurath, M., & Zopf, Y. (2022). “HIIT the Inflammation”: Comparative Effects of Low-Volume Interval Training and Resistance Exercises on Inflammatory Indices in Obese Metabolic Syndrome Patients Undergoing Caloric Restriction . Nutrients , 14 (10). https://dx.doi.org/10.3390/nu14101996
Reljic, D., Eichhorn, A., Herrmann, H.J., Neurath, M., & Zopf, Y. (2022). Very Low-Volume, High-Intensity Interval Training Mitigates Negative Health Impacts of COVID-19 Pandemic-Induced Physical Inactivity . International Journal of Environmental Research and Public Health , 19 (19). https://dx.doi.org/10.3390/ijerph191912308
Reljic, D., Herrmann, H.J., Jakobs, B., Dieterich, W., Mougiakakos, D., Neurath, M., & Zopf, Y. (2022). Feasibility, Safety, and Preliminary Efficacy of Very Low-Volume Interval Training in Advanced Cancer Patients . Medicine and science in sports and exercise , 54 (11), 1817-1830. https://dx.doi.org/10.1249/MSS.0000000000002989
Reljic, D., Zieseniss, N., Herrmann, H.J., Neurath, M., & Zopf, Y. (2022). Protein Supplementation Does Not Maximize Adaptations to Low-Volume High-Intensity Interval Training in Sedentary, Healthy Adults: A Placebo-Controlled Double-Blind Randomized Study . Nutrients , 14 (19). https://dx.doi.org/10.3390/nu14193883
Schmalzl, A., Leupold, T., Kreiß, L., Waldner, M., Schürmann, S., Neurath, M.,... Wirtz, S. (2022). Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection . Nature Communications , 13 (1). https://dx.doi.org/10.1038/s41467-022-33326-5
Schneider, I., Allner, C., Mühl, L., Melde, M., Lissner, D., Mantzivi, E.,... Zundler, S. (2022). Expression and function of α4β7 integrin predict the success of vedolizumab treatment in inflammatory bowel disease . Translational Research . https://dx.doi.org/10.1016/j.trsl.2022.10.003
Schweda, A., Becker, E., Wiendl, M., Atreya, R., Atreya, I., Müller, T.,... Zundler, S. (2022). Etrolizumab-s Does Not Induce Residual Trafficking of Regulatory T Cells . Inflammatory Bowel Diseases . https://dx.doi.org/10.1093/ibd/izac137
Simon, D., Tascilar, K., Fagni, F., Kleyer, A., Krönke, G., Meder, C.,... Hartmann, F. (2022). Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study. The Lancet Rheumatology , 4 (9), e614-e625. https://dx.doi.org/10.1016/S2665-9913(22)00191-6
Simon, D., Tascilar, K., Kleyer, A., Fagni, F., Krönke, G., Meder, C.,... Schett, G. (2022). Impact of Cytokine Inhibitor Therapy on the Prevalence, Seroconversion Rate, and Longevity of the Humoral Immune Response Against SARS-CoV-2 in an Unvaccinated Cohort . Arthritis and Rheumatology . https://dx.doi.org/10.1002/art.42035
Tascilar, K., Fagni, F., Kleyer, A., Bayat, S., Heidemann, R., Steiger, F.,... Simon, D. (2022). NON-INVASIVE IN VIVO METABOLIC PROFILING OF INFLAMMATION IN JOINTS AND ENTHESES BY OPTOACOUSTIC IMAGING . In ANNALS OF THE RHEUMATIC DISEASES (pp. 1032-1032). LONDON: BMJ PUBLISHING GROUP.
Tascilar, K., Fagni, F., Kleyer, A., Bayat, S., Heidemann, R., Steiger, F.,... Simon, D. (2022). Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography . Rheumatology . https://dx.doi.org/10.1093/rheumatology/keac346
Tascilar, K., Simon, D., Kleyer, A., Fagni, F., Krönke, G., Meder, C.,... Schett, G. (2022). LONG-TERM HUMORAL RESPONSE TO SARS-COV-2 VACCINATION IN PATIENTS WITH IMMUNE-MEDIATED INFLAMMATORY DISEASE . In ANNALS OF THE RHEUMATIC DISEASES (pp. 371-372). LONDON: BMJ PUBLISHING GROUP.
Vieth, M., & Neurath, M. (2022). Cold or hot snare in endoscopy - that is the question . Endoscopy International Open , 10 (05), E580-E581. https://dx.doi.org/10.1055/a-1776-7685
Vitali, F., Morgenstern, N., Eckstein, M., Atreya, R., Waldner, M., Hartmann, A.,... Rath, T. (2022). Endocytoscopy for assessing histologic inflammation in ulcerative colitis: development and prospective validation of the ELECT (ErLangen Endocytoscopy in ColiTis) score (with videos) . Gastrointestinal Endoscopy . https://dx.doi.org/10.1016/j.gie.2022.08.023
Voskens, C., Stoica, D., Rosenberg, M., Vitali, F., Zundler, S., Ganslmayer, M.,... Neurath, M. (2022). Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis . Gut . https://dx.doi.org/10.1136/gutjnl-2022-327075
Waldner, M., & Neurath, M. (2022). Molecular Endoscopy for the Diagnosis and Therapeutic Monitoring of Colorectal Cancer . Frontiers in Oncology , 12 . https://dx.doi.org/10.3389/fonc.2022.835256
Wildner, D., Pfeifer, L., Vitali, F., Neurath, M., & Albrecht, H. (2022). Transabdominal ultrasonography for confirmation of accurate percutaneous endoscopic gastrostomy tube placement: analysis of patient- and procedure-related complications . Medical Ultrasonography , 24 (4), 399-405. https://dx.doi.org/10.11152/mu-3672
Yu, Y., Herrmann, A., Thonn, V., Cordsmeier, A., Neurath, M., Enßer, A., & Becker, C. (2022). SMYD2 Inhibition Downregulates TMPRSS2 and Decreases SARS-CoV-2 Infection in Human Intestinal and Airway Epithelial Cells . Cells , 11 (8). https://dx.doi.org/10.3390/cells11081262
Yu, Y., Thonn, V., Patankar, J., Thoma, O.-M., Waldner, M., Zielinska, M.,... Becker, C. (2022). SMYD2 targets RIPK1 and restricts TNF-induced apoptosis and necroptosis to support colon tumor growth . Cell Death & Disease , 13 (1). https://dx.doi.org/10.1038/s41419-021-04483-0
Zundler, S., Günther, C., Kremer, A.E., Rothhammer, V., Neurath, M., & Zaiss, M. (2022). Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation . Nature Reviews Gastroenterology & Hepatology . https://dx.doi.org/10.1038/s41575-022-00663-1
Zundler, S., Mardin, C., Bertz, S., Vitali, F., Strauss, R., Fürst, J.,... Strobel, D. (2022). Rectal Cancer Presenting with Absceding Infection Due to Fusobacterium nucleatum . Pathogens , 11 (10). https://dx.doi.org/10.3390/pathogens11101113
Zundler, S., Schulze, L., & Neurath, M. (2022). Controlling in and out - the future of interfering with immune cell trafficking in inflammatory bowel disease . Expert Review of Clinical Immunology . https://dx.doi.org/10.1080/1744666X.2023.2152794
2021
Al-Zaher, N., Vitali, F., Neurath, M., & Görtz, R. (2021). The Positive Rate of Pulmonary Embolism by CT Pulmonary Angiography Is High in an Emergency Department, even in Low-Risk or Young Patients . Medical Principles and Practice , 30 (1), 37-44. https://dx.doi.org/10.1159/000511464
Atreya, R., & Neurath, M. (2021). Can Serum Proteomic Profiling Annunciate Individual Disease Progression in Newly Diagnosed Inflammatory Bowel Disease Patients? Journal of Crohns & Colitis , 15 (5), 697-698. https://dx.doi.org/10.1093/ecco-jcc/jjab009
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Drobny, A., Ngo, P.A., Neurath, M., Zunke, F., & Lopez-Posadas, R. (2021). Molecular Communication Between Neuronal Networks and Intestinal Epithelial Cells in Gut Inflammation and Parkinson's Disease . Frontiers in Medicine , 8 . https://dx.doi.org/10.3389/fmed.2021.655123
Düll, M., Wolf, K., Vetter, M., Dietrich, P., Neurath, M., & Kremer, A. (2021). Endogenous Opioid Levels Do Not Correlate With Itch Intensity and Therapeutic Interventions in Hepatic Pruritus . Frontiers in Medicine , 8 . https://dx.doi.org/10.3389/fmed.2021.641163
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Enderle, K., Dinkel, M., Spath, E.-M., Schmid, B., Zundler, S., Tripal, P.,... Neufert, C. (2021). Dynamic imaging of iel-iec co-cultures allows for quantification of cd103-dependent t cell migration . International Journal of Molecular Sciences , 22 (10). https://dx.doi.org/10.3390/ijms22105148
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Hoffman, A., Atreya, R., Rath, T., & Neurath, M. (2021). Current Endoscopic Resection Techniques for Gastrointestinal Lesions: Endoscopic Mucosal Resection, Submucosal Dissection, and Full-Thickness Resection . Visceral Medicine . https://dx.doi.org/10.1159/000515354
Jefremow, A., & Neurath, M. (2021). New agents for immunosuppression . Best Practice & Research in Clinical Gastroenterology . https://dx.doi.org/10.1016/j.bpg.2021.101763
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Neurath, M., & Vieth, M. (2021). Gastric hyperplastic polyps (hyperplasiogenic polyps): a constant debate! Endoscopy , 53 (01), 100-100. https://dx.doi.org/10.1055/a-1217-0521
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Reljic, D., Frenk, F., Herrmann, H.J., Neurath, M., & Zopf, Y. (2021). Effects of very low volume high intensity versus moderate intensity interval training in obese metabolic syndrome patients: a randomized controlled study . Scientific Reports , 11 (1). https://dx.doi.org/10.1038/s41598-021-82372-4
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Wirtz, S., Schulz-Kuhnt, A., Neurath, M., & Atreya, I. (2021). Functional Contribution and Targeted Migration of Group-2 Innate Lymphoid Cells in Inflammatory Lung Diseases: Being at the Right Place at the Right Time . Frontiers in Immunology , 12 . https://dx.doi.org/10.3389/fimmu.2021.688879
Wolf, K., Kühn, H., Boehm, F., Gebhardt, L., Glaudo, M., Agelopoulos, K.,... Kremer, A. (2021). A group of cationic amphiphilic drugs activates MRGPRX2 and induces scratching behavior in mice . Journal of Allergy and Clinical Immunology . https://dx.doi.org/10.1016/j.jaci.2020.12.655
Wolf, K., Kühn, H., Leibl, V., Gebhardt, L., Glaudo, M., Reeh, P.,... Kremer, A. (2021). The G protein-coupled receptor MRGX4 is a novel receptor for bile salts expressed on sensory neurons . In SWISS MEDICAL WEEKLY (pp. 11-11). MUTTENZ: E M H SWISS MEDICAL PUBLISHERS LTD.
2020
Abdullah, A., Neurath, M., & Atreya, R. (2020). Mild COVID-19 Symptoms in an Infliximab-Treated Ulcerative Colitis Patient: Can Ongoing Anti-TNF Therapy Protect against the Viral Hyperinflammatory Response and Avoid Aggravated Outcomes? Visceral Medicine . https://dx.doi.org/10.1159/000508740
Allner, C., Melde, M., Becker, E., Fuchs, F., Mühl, L., Klenske, E.,... Zundler, S. (2020). Baseline levels of dynamic CD4+ T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study . BMC Gastroenterology , 20 (1), 103-. https://dx.doi.org/10.1186/s12876-020-01253-8
Atreya, R., Neurath, M., & Siegmund, B. (2020). Personalizing Treatment in IBD: Hype or Reality in 2020? Can We Predict Response to Anti-TNF? Frontiers in Medicine , 7 . https://dx.doi.org/10.3389/fmed.2020.00517
Atreya, R., Peyrin-Biroulet, L., Klymenko, A., Augustyn, M., Bakulin, I., Slankamenac, D.,... Reinisch, W. (2020). Cobitolimod for Moderate-to-Severe Left-Sided Ulcerative Colitis (CONDUCT): A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Trial . In AMERICAN JOURNAL OF GASTROENTEROLOGY (pp. S322-S322). PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
Atreya, R., Peyrin-Biroulet, L., Klymenko, A., Augustyn, M., Bakulin, I., Slankamenac, D.,... Reinisch, W. (2020). Cobitolimod for moderate-to-severe, left-sided ulcerative colitis (CONDUCT): a phase 2b randomised, double-blind, placebo-controlled, dose-ranging induction trial . Lancet Gastroenterology and Hepatology , 5 (12), 1063-1075. https://dx.doi.org/10.1016/S2468-1253(20)30301-0
Baer, E., Jesper, D., Neurath, M., & Atreya, R. (2020). Morbus Crohn und Colitis ulcerosa in der Hausarztpraxis . MMW Fortschritte der Medizin , 162 , 51-58. https://dx.doi.org/10.1007/s15006-020-1202-4
Baronetto, A., Graf, L., Fischer, S., Neurath, M., & Amft, O. (2020). GastroDigitalShirt: A smart shirt for digestion acoustics monitoring . In Proceedings - International Symposium on Wearable Computers, ISWC (pp. 17-21). Association for Computing Machinery.
Becker, E., Wiendl, M., Schulz-Kuhnt, A., Atreya, I., Atreya, R., Neurath, M., & Zundler, S. (2020). Dose-dependent differential effects of vedolizumab therapy on adhesion of regulatory and effector T cells . In JOURNAL OF CROHNS & COLITIS (pp. S165-S166). OXFORD: OXFORD UNIV PRESS.
Breidert, M., Eftekhari, P., Louis, F., Rotoiu, C., Rath, T., Neurath, M., & Atreya, R. (2020). Functional molecular network analysis enables prediction of response to vedolizumab therapy in anti-TNF refractory IBD patients . Crohn's & Colitis 360 , 2 (2). https://dx.doi.org/10.1093/crocol/otaa037
Danese, S., Neurath, M., Kopoń, A., Zakko, S.F., Simmons, T.C., Fogel, R.,... Chitkara, D. (2020). Effects of Apremilast, an Oral Inhibitor of Phosphodiesterase 4, in a Randomized Trial of Patients With Active Ulcerative Colitis . Clinical Gastroenterology and Hepatology , 18 (11), 2526-2534.e9. https://dx.doi.org/10.1016/j.cgh.2019.12.032
Dieterich, W., Neurath, M., & Zopf, Y. (2020). Intestinal ex vivo organoid culture reveals altered programmed crypt stem cells in patients with celiac disease . Scientific Reports , 10 (1). https://dx.doi.org/10.1038/s41598-020-60521-5
Dietrich, P., Wormser, L., Fritz, V., Seitz, T., de Maria, M., Schambony, A.,... Hellerbrand, C. (2020). Molecular cross-talk between Y5-receptor and neuropeptide Y drives liver cancer . Journal of Clinical Investigation , 130 (5), 2509-2526. https://dx.doi.org/10.1172/JCI131919
Fischer, S., Mesfin, S.E., Klenske, E., Schmitt, H., Vitali, F., Hirschmann, S.,... Atreya, R. (2020). Efficacy, safety, and pharmacokinetics after switching from infliximab originator to biosimilar SB2 in inflammatory bowel disease patients: A long-term observational, prospective cohort study . In JOURNAL OF CROHNS & COLITIS (pp. S466-S467). OXFORD: OXFORD UNIV PRESS.
Fischer, S., & Neurath, M. (2020). „Ich habe Durchfall und Erbrechen“ . MMW Fortschritte der Medizin , 162 (1), 39-43. https://dx.doi.org/10.1007/s15006-020-0059-x
Fournier, A.P., De Lizarrondo, S.M., Rateau, A., Gerard-Brisou, A., Waldner, M., Neurath, M.,... Gauberti, M. (2020). Ultrasensitive molecular imaging of intestinal mucosal inflammation using leukocyte-mimicking particles targeted to MAdCAM-1 in mice . Science Translational Medicine , 12 (560). https://dx.doi.org/10.1126/scitranslmed.aaz4047
Ganzleben, I., Geppert, C.-I., Osaba, L., Hirschmann, S., Nägel, A., Glück, C.,... Atreya, R. (2020). Successful cyclosporin and ustekinumab combination therapy in a patient with severe steroid-refractory ulcerative colitis . Therapeutic Advances in Gastroenterology , 13 . https://dx.doi.org/10.1177/1756284820954112
Ganzleben, I., Hirschmann, S., Köhler, J., Fuchs, F., Rieker, R., Baer, E.,... Atreya, R. (2020). Successful Therapy of Crohn's Disease-Associated Pulmonary Necrobiotic Nodules on Ustekinumab Therapy . American Journal of Gastroenterology , 115 (4), 632-634. https://dx.doi.org/10.14309/ajg.0000000000000571
Ganzleben, I., Hohmann, M., Grünberg, A., Menezes, J.G., Liebing, E., Günther, C.,... Vieth, M. (2020). Topical application of Chlorin e6-PVP (Ce6-PVP) for improved endoscopic detection of neoplastic lesions in a murine colitis-associated cancer model . Scientific Reports , 10 (1). https://dx.doi.org/10.1038/s41598-020-69570-2
Görtz, R., Atreya, R., & Neurath, M. (2020). Recurrent Ileal Invagination in Crohn's Disease . Deutsches Ärzteblatt international , 117 (9), 146-146. https://dx.doi.org/10.3238/arztebl.2020.0146
Görtz, R., Hensel, S., Wildner, D., Neurath, M., & Strobel, D. (2020). Bowel wall thickening and hyperemia assessed by high-frequency ultrasound indicate histological inflammation in Crohn's ileitis . Abdominal Radiology . https://dx.doi.org/10.1007/s00261-020-02895-8
Hagel, A., Raithel, M., Hempen, P., Preclik, G., Dauth, W., Neurath, M.,... Albrecht, H. (2020). MULTICENTER ANALYSIS OF ENDOCLOT AS HEMOSTATIC POWDER IN DIFFERENT ENDOSCOPIC SETTINGS OF THE UPPER GASTROINTESTINAL TRACT . Journal of Physiology and Pharmacology , 71 (5). https://dx.doi.org/10.26402/jpp.2020.5.06
Hartmann, L., Siegmund, B., Weidinger, C., Becker, C., Neurath, M., & Günther, C. (2020). An IFN-STAT1-MLKL axis drives programmed necrosis of Paneth cells in Crohn's ileitis . In JOURNAL OF CROHNS & COLITIS (pp. S125-S125). OXFORD: OXFORD UNIV PRESS.
Hoffman, A., Atreya, R., Rath, T., & Neurath, M. (2020). Use of Fluorescent Dyes in Endoscopy and Diagnostic Investigation . Visceral Medicine . https://dx.doi.org/10.1159/000506241
Jefremow, A., & Neurath, M. (2020). All are Equal, Some are More Equal: Targeting IL 12 and 23 in IBD - A Clinical Perspective . ImmunoTargets and Therapy , 9 , 289-297. https://dx.doi.org/10.2147/ITT.S282466
Jefremow, A., & Neurath, M. (2020). Nanoparticles in Gastrooncology . Visceral Medicine . https://dx.doi.org/10.1159/000506908
Jefremow, A., & Neurath, M. (2020). SARS-CoV-2 Virus Manifestations in the Gastrointestinal Tract: Therapeutic Implications . Visceral Medicine . https://dx.doi.org/10.1159/000513180
Jefremow, A., Wiesmüller, M., Rouse, R.A., Dietrich, P., Kremer, A., Waldner, M.,... Siebler, J. (2020). Beyond the border: The use of lenvatinib in advanced hepatocellular carcinoma after different treatment lines: A retrospective analysis . Journal of Physiology and Pharmacology , 71 (5), 717-728. https://dx.doi.org/10.26402/jpp.2020.5.11
Jefremow, A., Wiesmüller, M., Rouse, R.A., Dietrich, P., Kremer, A., Waldner, M.,... Siebler, J. (2020). Efficiency and Toxicity of Lenvatinib in Advanced HCC in Later Treatment Lines . In ONCOLOGY RESEARCH AND TREATMENT (pp. 216-216). BASEL: KARGER.
Jesper, D., Klett, D., Schellhaas, B., Pfeifer, L., Leppkes, M., Waldner, M.,... Strobel, D. (2020). Ultrasound-Based Attenuation Imaging for the Non-Invasive Quantification of Liver Fat-A Pilot Study on Feasibility and Inter-Observer Variability . IEEE Journal of Translational Engineering in Health and Medicine , 8 . https://dx.doi.org/10.1109/JTEHM.2020.3001488
Kindermann, M., Knipfer, L., Obermeyer, S., Müller, U., Alber, G., Bogdan, C.,... Wirtz, S. (2020). Group 2 Innate Lymphoid Cells (ILC2) Suppress Beneficial Type 1 Immune Responses During Pulmonary Cryptococcosis . Frontiers in Immunology , 11 . https://dx.doi.org/10.3389/fimmu.2020.00209
Klenske, E., Hartmann, A., Atreya, R., Neurath, M., & Rath, T. (2020). Perforations after routine biopsy in IBD patients, their management and potential risk reductions by microscopic imaging with endocytoscopy . Journal of Gastrointestinal and Liver Diseases , 29 (3), 465-466. https://dx.doi.org/10.15403/jgld-2267
Konturek, P.C., Harsch, I.A., Neurath, M., & Zopf, Y. (2020). COVID-19 - more than respiratory disease: a gastroenterologist's perspective. Journal of Physiology and Pharmacology , 71 (2). https://dx.doi.org/10.26402/jpp.2020.2.02
Konturek, P.C., Konturek, K., Brzozowski, T., Wojcik, D., Magierowski, M., Targosz, A.,... Zopf, Y. (2020). Participation of the intestinal microbiota in the mechanism of beneficial effect of treatment with synbiotic syngut on experimental colitis under stress conditions . Journal of Physiology and Pharmacology , 71 (3), 1-14. https://dx.doi.org/10.26402/jpp.2020.3.03
Kreiß, L., Thoma, O.M., Dilipkumar, A., Carlé, B.-E., Longequeue, P., Kunert, T.,... Vieth, M. (2020). Label-Free In Vivo Histopathology of Experimental Colitis via 3-Channel Multiphoton Endomicroscopy . Gastroenterology . https://dx.doi.org/10.1053/j.gastro.2020.05.081
Kühn, H., Kappes, L., Wolf, K., Gebhardt, L., Neurath, M., Reeh, P.,... Kremer, A. (2020). Complementary roles of murine NaV1.7, NaV1.8 and NaV1.9 in acute itch signalling . Scientific Reports , 10 (1). https://dx.doi.org/10.1038/s41598-020-59092-2
Lang-Schwarz, C., Agaimy, A., Atreya, R., Becker, C., Danese, S., Flejou, J.-F.,... Vieth, M. (2020). Maximizing the diagnostic information from biopsies in chronic inflammatory bowel diseases: recommendations from the Erlangen International Consensus Conference on Inflammatory Bowel Diseases and presentation of the IBD-DCA score as a proposal for a new index for histologic activity assessment in ulcerative colitis and Crohn's disease . Virchows Archiv . https://dx.doi.org/10.1007/s00428-020-02982-7
Lechner, K.S., Neurath, M., & Weigmann, B. (2020). Role of the IL-2 inducible tyrosine kinase ITK and its inhibitors in disease pathogenesis . Journal of Molecular Medicine . https://dx.doi.org/10.1007/s00109-020-01958-z
Leppkes, M., Knopf, J., Naschberger, E., Lindemann, A., Singh, J., Herrmann, I.,... Schauer, C. (2020). Vascular occlusion by neutrophil extracellular traps in COVID-19 . EBioMedicine , 58 . https://dx.doi.org/10.1016/j.ebiom.2020.102925
Leppkes, M., & Neurath, M. (2020). Cytokines in inflammatory bowel diseases – Update 2020 . Pharmacological Research , 158 . https://dx.doi.org/10.1016/j.phrs.2020.104835
Martínez Sánchez, L.d.C., Pradhan, R., Ngo, P.A., Erkert, L., Becker, L., Watson, A.J.,... Lopez Posadas, R. (2020). An intravital microscopy-based approach to assess intestinal permeability and epithelial cell shedding performance . Journal of Visualized Experiments , 2020 (166), 1-12. https://dx.doi.org/10.3791/60790
Mortier, E., Ma, A., Malynn, B.A., & Neurath, M. (2020). Editorial: Modulating Cytokines as Treatment for Autoimmune Diseases and Cancer . Frontiers in Immunology , 11 . https://dx.doi.org/10.3389/fimmu.2020.608636
Neufert, C., Heichler, C., Brabletz, T., Scheibe, K., Boonsanay, V., Greten, F.R., & Neurath, M. (2020). Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis . Nature Protocols . https://dx.doi.org/10.1038/s41596-020-00412-1
Neurath, M. (2020). Covid-19 and immunomodulation in IBD . Gut . https://dx.doi.org/10.1136/gutjnl-2020-321269
Neurath, M. (2020). IL-36 in chronic inflammation and cancer . Cytokine & Growth Factor Reviews . https://dx.doi.org/10.1016/j.cytogfr.2020.06.006
Rath, T., Morgenstern, N., Vitali, F., Atreya, R., & Neurath, M. (2020). Advanced Endoscopic Imaging in Colonic Neoplasia . Visceral Medicine . https://dx.doi.org/10.1159/000505411
Rath, T., Neurath, M., & Atreya, R. (2020). Molecular imaging in inflammatory bowel disease . Elsevier.
Rath, T., Pfeifer, L., Neufert, C., Kremer, A., Leppkes, M., Hoffman, A.,... Zopf, S. (2020). Retrograde inspection vs standard forward view for the detection of colorectal adenomas during colonoscopy: A back-to-back randomized clinical trial . World Journal of Gastroenterology , 26 (16), 1962-1970. https://dx.doi.org/10.3748/wjg.v26.i16.1962
Reljic, D., Frenk, F., Herrmann, H.J., Neurath, M., & Zopf, Y. (2020). Low-volume high-intensity interval training improves cardiometabolic health, work ability and well-being in severely obese individuals: a randomized-controlled trial sub-study . Journal of Translational Medicine , 18 (1). https://dx.doi.org/10.1186/s12967-020-02592-6
Reljic, D., Konturek, P., Herrmann, H.J., Neurath, M., & Zopf, Y. (2020). Effects of whole-body electromyostimulation exercise and caloric restriction on cardiometabolic risk profile and muscle strength in obese women with the metabolic syndrome: a pilot study . Journal of Physiology and Pharmacology , 71 (1). https://dx.doi.org/10.26402/jpp.2020.1.08
Reljic, D., Zarafat, D., Jensen, B., Herrmann, H.J., Neurath, M., Konturek, P.C., & Zopf, Y. (2020). Phase angle and vector analysis from multifrequency segmental bioelectrical impedance analysis: New reference data for older adults . Journal of Physiology and Pharmacology , 71 (4), 1-9. https://dx.doi.org/10.26402/jpp.2020.4.04
Ruder, B., Günther, C., Stürzl, M., Neurath, M., Cesarman, E., Ballon, G., & Becker, C. (2020). Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo . PLoS ONE , 15 (1). https://dx.doi.org/10.1371/journal.pone.0228441
Scarozza, P., Marafini, I., Laudisi, F., Troncone, E., Schmitt, H., Lenti, M.V.,... Monteleone, G. (2020). Extent of Mucosal Inflammation in Ulcerative Colitis Influences the Clinical Remission Induced by Vedolizumab . Journal of Clinical Medicine , 9 (2). https://dx.doi.org/10.3390/jcm9020385
Schalk, P., Kohl, M., Herrmann, H.J., Schwappacher, R., Rimmele, M., Büttner, A.,... Siebler, J. (2020). Correction to: Influence of cancer and acute inflammatory disease on taste perception: a clinical pilot study (Supportive Care in Cancer, (2019), 27, 4, (1579), 10.1007/s00520-019-4642-6) . Supportive Care in Cancer . https://dx.doi.org/10.1007/s00520-020-05327-x
Schett, G., Sticherling, M., & Neurath, M. (2020). COVID-19: risk for cytokine targeting in chronic inflammatory diseases? Nature Reviews Immunology . https://dx.doi.org/10.1038/s41577-020-0312-7
Schmitt, H., Ulmschneider, J., Billmeier, U., Scarozza, P., Sonnewald, S., Reid, S.,... Vieth, M. (2020). The TLR9 agonist cobitolimod induces IL10 producing wound healing macrophages and regulatory T cells in ulcerative colitis . Journal of Crohns & Colitis , 14 (4), 508-524. https://dx.doi.org/10.1093/ecco-jcc/jjz170
Schulz-Kuhnt, A., Greif, V., Hildner, K., Knipfer, L., Döbrönti, M., Zirlik, S.,... Atreya, I. (2020). ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure . Frontiers in Immunology , 11 . https://dx.doi.org/10.3389/fimmu.2020.00691
Schulz-Kuhnt, A., Wirtz, S., Neurath, M., & Atreya, I. (2020). Regulation of Human Innate Lymphoid Cells in the Context of Mucosal Inflammation . Frontiers in Immunology , 11 . https://dx.doi.org/10.3389/fimmu.2020.01062
Schwappacher, R., Schink, K., Sologub, S., Dieterich, W., Reljic, D., Friedrich, O.,... Zopf, Y. (2020). Physical activity and advanced cancer: evidence of exercise-sensitive genes regulating prostate cancer cell proliferation and apoptosis . The Journal of Physiology . https://dx.doi.org/10.1113/JP279150
Simon, D., Tascilar, K., Krönke, G., Kleyer, A., Zaiss, M., Heppt, F.,... Ramming, A. (2020). Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion . Nature Communications , 11 (1). https://dx.doi.org/10.1038/s41467-020-17703-6
Simon, D., Tascilar, K., Krönke, G., Kleyer, A., Zaiss, M., Heppt, F.,... Schett, G. (2020). Patients Receiving Cytokine Inhibitors Have Low Prevalence of SARS-CoV-2 Infection . In ARTHRITIS & RHEUMATOLOGY . HOBOKEN: WILEY.
Staats, L.A.N., Pfeiffer, H., Knopf, J., Lindemann, A., Fürst, J., Kremer, A.,... Steffen, U. (2020). IgA2 Antibodies against SARS-CoV-2 Correlate with NET Formation and Fatal Outcome in Severely Diseased COVID-19 Patients . Cells , 9 (12). https://dx.doi.org/10.3390/cells9122676
Ullrich, K., Schulze, L., Paap, E.-M., Müller, T., Neurath, M., & Zundler, S. (2020). IMMUNOLOGY OF IL-12: AN UPDATE ON FUNCTIONAL ACTIVITIES AND IMPLICATIONS FOR DISEASE . Excli Journal , 19 , 1563-1589. https://dx.doi.org/10.17179/excli2020-3104
Vetter, M., Kremer, A., Agaimy, A., Pfeifer, L., Neurath, M., Zopf, S., & Siebler, J. (2020). How Much Liver Tissue Is Required for Sufficient Histological Staging in Patients with Primary Biliary Cholangitis? Digestion . https://dx.doi.org/10.1159/000507392
Yu, Y., Zielinska, M., Li, W., Bernkopf, D., Heilingloh, C., Neurath, M., & Becker, C. (2020). PGAM5-MAVS interaction regulates TBK1/ IRF3 dependent antiviral responses . Scientific Reports , 10 (1). https://dx.doi.org/10.1038/s41598-020-65155-1
Zopf, Y., Schink, K., Reljic, D., Herrmann, H.J., Dieterich, W., Kießwetter, E.,... Volkert, D. (2020). Assessing cachexia in older patients: Different definitions – But which one is the most practical for clinical routine? Archives of gerontology and geriatrics , 86 . https://dx.doi.org/10.1016/j.archger.2019.103943
Zundler, S., Tauschek, V., & Neurath, M. (2020). Immune Cell Circuits in Mucosal Wound Healing: Clinical Implications . Visceral Medicine . https://dx.doi.org/10.1159/000506846
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Smurf2-dependent repression of type I IFN signalling in inflammatory bowel disease and mucosal healing
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