The scientific focus of the Department of Neuroradiology is on multimodal imaging, especially in stroke, brain tumors, focal epilepsies, MS and dementia and on the minimally invasive treatment of cerebral aneurysms, vascular malformation, stenosis and acute stroke using state-of-the-art imaging technology including innovative flat-panel imaging and clinically approved ultrahigh-field 7 Tesla MRI.
Research projects
Department of Neuroradiology, University Hospital Erlangen, FAU
Professorship for Neuroradiology (Chair; W3)
Professorship for multimodal clinical imaging (W2; Prof. Zaiss)
Multimodal imaging of cerebrovascular diseases, epilepsy, neurooncology and neurodegenerative disease
7 Tesla Ultrahigh-field-neuroimaging
Functional and metabolic MR-imaging
Minimally invasive neurovascular and spinal interventions and interventional imaging
AI applications in neuroimaging
Current projects Current projects
Recent publications Recent publications
2023
Eisenhut, F., Schmidt, M., Buchfelder, M., Dörfler, A., & Schlaffer, S.-M. (2023). Improved Detection of Cavernous Sinus Invasion of Pituitary Macroadenomas with Ultra-High-Field 7 T MRI . Life , 13 (1). https://dx.doi.org/10.3390/life13010049
Herrler, J., Williams, S.N., Liebig, P., Ding, B., McElhinney, P., Allwood-Spiers, S.,... Maier, A. (2023). The effects of RF coils and SAR supervision strategies for clinically applicable nonselective parallel-transmit pulses at 7 T . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.29569
Hölter, P., Lang, S., Beuscher, V., Kallmünzer, B., Manhart, M., Schwab, S., & Dörfler, A. (2023). Extended Multimodal Flat Detector CT Imaging in Acute Ischemic Stroke: A Pilot Study . Journal of Digital Imaging . https://dx.doi.org/10.1007/s10278-022-00699-4
Osmanodja, F., Rösch, J., Knott, M., Dörfler, A., Grodzki, D., Uder, M., & Heiß, R. (2023). Diagnostic Performance of 0.55 T MRI for Intracranial Aneurysm Detection . Investigative Radiology , 58 (2), 121-125. https://dx.doi.org/10.1097/RLI.0000000000000918
Winder, K., Villegas Millar, C., Siedler, G., Knott, M., Dörfler, A., Engel, A.,... Fröhlich, K. (2023). Acute right insular ischaemic lesions and poststroke left ventricular dysfunction . Stroke and Vascular Neurology . https://dx.doi.org/10.1136/svn-2022-001724
2022
Borutta, M., Gerner, S.T., Möser, P., Hölter, P., Engelhorn, T., Dörfler, A.,... Köhn, J. (2022). Correlation between clinical severity and extent of autonomic cardiovascular impairment in the acute phase of subarachnoid hemorrhage . Journal of Neurology . https://dx.doi.org/10.1007/s00415-022-11220-w
Dinkel, J., Lahmer, G., Mennecke, A., Hock, S., Richter-Schmidinger, T., Fietkau, R.,... Schmidt, M. (2022). Effects of Hippocampal Sparing Radiotherapy on Brain Microstructure—A Diffusion Tensor Imaging Analysis . Brain Sciences , 12 (7). https://dx.doi.org/10.3390/brainsci12070879
Dörfler, A., Huang, Y., Bert, C., Sommer, P., Frey, B., Gaipl, U.,... Putz, F. (2022). Improvement of Deep Learning-based Auto-detection of Brain Metastases by Integrating previous MRI Images . In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S6-S6). HEIDELBERG: SPRINGER HEIDELBERG.
Eisenhut, F., Heidelbach, C., Heynold, E., Manhart, M., Struffert, T., Brandner, S.,... Lang, S. (2022). Clinical Comparison of FD-CT and MS-CT in Aneurysmal Subarachnoid Haemorrhage: A Single Center Experience . Diagnostics , 12 (10). https://dx.doi.org/10.3390/diagnostics12102443
Eisenhut, F., Manhart, M., Thimsen, V., Mantsopoulos, K., Iro, H., Hornung, J.,... Taha, L. (2022). High-speed flat-detector computed tomography for temporal bone imaging and postoperative control of cochlear implants . Neuroradiology . https://dx.doi.org/10.1007/s00234-022-02940-x
Eisenhut, F., Schlaffer, S.-M., Hock, S., Heynold, E., Kremenevski, N., Blümcke, I.,... Schmidt, M. (2022). Ultra-High-Field 7 T Magnetic Resonance Imaging Including Dynamic and Static Contrast-Enhanced T1-Weighted Imaging Improves Detection of Secreting Pituitary Microadenomas . Investigative Radiology , 57 (9), 567-574. https://dx.doi.org/10.1097/RLI.0000000000000872
Eisenhut, F., Schmidt, M., Kalik, A., Struffert, T., Feulner, J., Schlaffer, S.-M.,... Lang, S. (2022). Clinical Evaluation of an Innovative Metal-Artifact-Reduction Algorithm in FD-CT Angiography in Cerebral Aneurysms Treated by Endovascular Coiling or Surgical Clipping . Diagnostics , 12 (5). https://dx.doi.org/10.3390/diagnostics12051140
Fröhlich, K., Knott, M., Hock, S., Dörfler, A., Seifert, F., & Winder, K. (2022). Voxel-wise lesion mapping of restless legs syndrome in multiple sclerosis . Neurological Sciences . https://dx.doi.org/10.1007/s10072-022-06103-x
Glang, F., Fabian, M.S., German, A., Khakzar, K., Mennecke, A., Liebert, A.,... Laun, F.B. (2022). Linear projection-based CEST parameter estimation . NMR in Biomedicine . https://dx.doi.org/10.1002/nbm.4697
Gölitz, P., Lücking, H., Knott, M., Hock, S., Brandner, S., Knossalla, F., & Dörfler, A. (2022). Microcatheters with extra-long detachable tip: A promising treatment option in dural arteriovenous fistulas . Interventional Neuroradiology . https://dx.doi.org/10.1177/15910199221130236
Hassan, A.E., Zaidat, O.O., Nanda, A., Atchie, B., Woodward, K., Dörfler, A.,... Complete Registry Investigators, . (2022). Impact of interhospital transfer vs. direct admission on acute ischemic stroke patients: A subset analysis of the COMPLETE registry . Frontiers in Neurology , 13 . https://dx.doi.org/10.3389/fneur.2022.896165
Hastreiter, P., Bischoff, B., Fahlbusch, R., Dörfler, A., Buchfelder, M., & Naraghi, R. (2022). Data fusion and 3D visualization for optimized representation of neurovascular relationships in the posterior fossa . Acta Neurochirurgica . https://dx.doi.org/10.1007/s00701-021-05099-1
Herfurth, K., Harpaz, Y., Rösch, J., Müller, N., Walther, K., Kaltenhaeuser, M.,... Rampp, S. (2022). Localization of beta power decrease as measure for lateralization in pre-surgical language mapping with magnetoencephalography, compared with functional magnetic resonance imaging and validated by Wada test . Frontiers in Human Neuroscience , 16 . https://dx.doi.org/10.3389/fnhum.2022.996989
Huang, Y., Bert, C., Sommer, P., Frey, B., Gaipl, U., Distel, L.,... Putz, F. (2022). Deep learning for brain metastasis detection and segmentation in longitudinal MRI data . Medical Physics . https://dx.doi.org/10.1002/mp.15863
Huang, Y., Bert, C., Sommer, P., Frey, B., Gaipl, U., Distel, L.,... Putz, F. (2022). Verbesserung der Deep Learning basierten Autodetektion von Hirnmetastasen durch Integration von MRT-Voraufnahmen . In Strahlentherapie und Onkologie (S. S6). Stuttgart, DE: Springer.
Hunger, L., Rajput, J.R., Klein, K., Mennecke, A., Fabian, M., Schmidt, M.,... Zaiß, M. (2022). DeepCEST 7 T: Fast and homogeneous mapping of 7 T CEST MRI parameters and their uncertainty quantification . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.29520
Knott, M., Hölter, P., Hock, S., Mühlen, I., Gerner, S., Sprügel, M.,... Dörfler, A. (2022). Can flat-detector CT after successful endovascular treatment predict long-term outcome in patients with large vessel occlusion? An Alberta Stroke Programme Early CT Score–based study . Neurological Sciences . https://dx.doi.org/10.1007/s10072-022-06511-z
Kulvait, V., Hölter, P., Frysch, R., Haseljic, H., Dörfler, A., & Rose, G. (2022). A novel use of time separation technique to improve flat detector CT perfusion imaging in stroke patients . Medical Physics . https://dx.doi.org/10.1002/mp.15640
Kulvait, V., Hölter, P., Punzet, D., Dörfler, A., & Rose, G. (2022). Noise and dose reduction in CT brain perfusion acquisition by projecting time attenuation curves onto lower dimensional spaces . In Wei Zhao, Lifeng Yu (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE . Virtual, Online: SPIE.
Kuramatsu, J., Gerner, S., Ziai, W., Bardutzky, J., Sembill, J., Sprügel, M.,... Huttner, H. (2022). Association of Intraventricular Fibrinolysis With Clinical Outcomes in Intracerebral Hemorrhage: An Individual Participant Data Meta-Analysis. Stroke , 53 (9), 2876-2886. https://dx.doi.org/10.1161/STROKEAHA.121.038455
Levy, S., Herrler, J., Liebert, A., Tkotz, K., Fabian, M., Eisen, C.,... Nagel, A.M. (2022). Clinically compatible subject-specific dynamic parallel transmit pulse design for homogeneous fat saturation and water-excitation at 141657T: Proof-of-concept for 14165CEST MRI of the brain . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.29412
Lücking, H., Hölter, P., Lang, S., Schmidt, M., Eisenhut, F., & Dörfler, A. (2022). Change your Angle of View Sinusoidal C-Arm Movement in Cranial Flat-panel CT to Improve Image Quality . Clinical Neuroradiology . https://dx.doi.org/10.1007/s00062-022-01172-z
Macha, K., Hölter, P., Sembill, J., Hock, S., Siedler, G., Mühlen, I.,... Dörfler, A. (2022). Influence of antithrombotic pre-treatment and time window on hemorrhagic complications of ivt in ischemic stroke . In EUROPEAN JOURNAL OF NEUROLOGY (pp. 550-550). HOBOKEN: WILEY.
Marterstock, D., Knott, M., Lang, S., Oberstein, T., Kornhuber, J., Dörfler, A.,... Hölter, P. (2022). Pulsed Arterial Spin Labeling and Segmented Brain Volumetry in the Diagnostic Evaluation of Frontotemporal Dementia, Alzheimer’s Disease and Mild Cognitive Impairment . Tomography , 8 (1), 229-244. https://dx.doi.org/10.3390/tomography8010018
Mennecke, A., Khakzar, K.M., German, A., Herz, K., Fabian, M., Liebert, A.,... Zaiß, M. (2022). 7 tricks for 7 T CEST: Improving the reproducibility of multipool evaluation provides insights into the effects of age and the early stages of Parkinson's disease . NMR in Biomedicine . https://dx.doi.org/10.1002/nbm.4717
Mühlen, I., Borutta, M., Siedler, G., Engelhorn, T., Hock, S., Knott, M.,... Dörfler, A. (2022). Prognostic Accuracy of CTP Summary Maps in Patients with Large Vessel Occlusive Stroke and Poor Revascularization after Mechanical Thrombectomy-Comparison of Three Automated Perfusion Software Applications . Tomography , 8 (3), 1350-1362. https://dx.doi.org/10.3390/tomography8030109
Mühlen, I., Sprügel, M., Hölter, P., Hock, S., Knott, M., Huttner, H.,... Dörfler, A. (2022). Comparison of Two Automated Computed Tomography Perfusion Applications to Predict the Final Infarct Volume After Thrombolysis in Cerebral Infarction 3 Recanalization . Stroke , 53 (5), 1657-1664. https://dx.doi.org/10.1161/STROKEAHA.121.035626
Müller, M., Egger, N., Sommer, S., Wilferth, T., Meixner, C., Laun, F.B.,... Nagel, A.M. (2022). Direct imaging of white matter ultrashort T2∗ components at 7 Tesla . Magnetic Resonance Imaging , 86 , 107-117. https://dx.doi.org/10.1016/j.mri.2021.11.016
Oberstein, T., Schmidt, M., Florvaag, A., Haas, A.-L., Siegmann, E.-M., Olm, P.,... Maler, J.M. (2022). Amyloid-beta levels and cognitive trajectories in non-demented pTau181-positive subjects without amyloidopathy . Brain . https://dx.doi.org/10.1093/brain/awac297
Reindl, C., Allgäuer, A., Kleiser, B., Onugoren, M.D., Lang, J., Welte, T.,... Walther, K. (2022). Resection of dominant fusiform gyrus is associated with decline of naming function when temporal lobe epilepsy manifests after the age of five: A voxel-based lesion-symptom mapping study . NeuroImage: Clinical , 35 . https://dx.doi.org/10.1016/j.nicl.2022.103129
Ruck, L., Mennecke, A., Wilferth, T., Lachner, S., Müller, M., Egger, N.,... Nagel, A.M. (2022). Influence of image contrasts and reconstruction methods on the classification of multiple sclerosis-like lesions in simulated sodium magnetic resonance imaging . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.29476
Sembill, J., Lusse, C., Linnerbauer, M., Sprügel, M., Mrochen, A., Knott, M.,... Kuramatsu, J. (2022). CEREBROSPINAL FLUID BIOMARKERS FOR CEREBRAL AMYLOID ANGIOPATHY . In INTERNATIONAL JOURNAL OF STROKE (pp. 8-8). LONDON: SAGE PUBLICATIONS LTD.
Sommer, P., Huang, Y., Fischer, S., Srinivasan, A.L., Dörfler, A., Schmidt, M.,... Putz, F. (2022). Identification of High-risk Metastases in MRI Follow-up after Stereotaxic by using Radiomics and Delta Radiomics . In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S64-S64). HEIDELBERG: SPRINGER HEIDELBERG.
Sommer, P., Huang, Y., Srinivasan, A.L., Fischer, S., Dörfler, A., Schmidt, M.,... Putz, F. (2022). Distinguishing Progression and Radionecrosis in large progressive Brain Metastases after Stereotaxy by integrating Radiomics, Dose Radiomics and clinical Risk Factors . In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S19-S20). HEIDELBERG: SPRINGER HEIDELBERG.
Sprügel, M., Sembill, J., Kremer, S., Gerner, S., Knott, M., Hock, S.,... Schwab, S. (2022). Evaluation of Functional Recovery Following Thrombectomy in Patients With Large Vessel Occlusion and Prestroke Disability . JAMA Network Open , 5 (8). https://dx.doi.org/10.1001/jamanetworkopen.2022.27139
Utz, K., Kohl, Z., Marterstock, D., Dörfler, A., Winkler, J., Schmidt, M., & Regensburger, M. (2022). Neuropsychology and MRI correlates of neurodegeneration in SPG11 hereditary spastic paraplegia . Orphanet Journal of Rare Diseases , 17 (1). https://dx.doi.org/10.1186/s13023-022-02451-1
Welte, T., Steidl, J., Stritzelberger, J., Gollwitzer, S., Lang, J., Reindl, C.,... Hamer, H. (2022). Surgical hematoma evacuation of cortical intracerebral hemorrhage ≥10 ml reduces risk of subsequent epilepsy by more than 70%: A retrospective monocenter study. European Journal of Neurology . https://dx.doi.org/10.1111/ene.15577
Wiendieck, K., Dörfler, A., & Sommer, B. (2022). Extended salvage surgery after high-dose chemoradiation therapy for tumors in the cervico-thoracic junction with invasion of the chest wall and the spine: a case series . Journal of Surgical Case Reports , 2022 (12). https://dx.doi.org/10.1093/jscr/rjac581
Wilferth, T., Mennecke, A., Gast, L., Lachner, S., Müller, M., Rothhammer, V.,... Schmidt, M. (2022). Quantitative 7T sodium magnetic resonance imaging of the human brain using a 32-channel phased-array head coil: Application to patients with secondary progressive multiple sclerosis . NMR in Biomedicine . https://dx.doi.org/10.1002/nbm.4806
Wilferth, T., Müller, M., Gast, L., Ruck, L., Meyerspeer, M., Kolkovsky, A.L.L.,... Nagel, A.M. (2022). Motion-corrected 23Na MRI of the human brain using interleaved 1H 3D navigator images . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.29221
Zaidat, O.O., Fifi, J.T., Nanda, A., Atchie, B., Woodward, K., Dörfler, A.,... Hassan, A.E. (2022). Endovascular Treatment of Acute Ischemic Stroke With the Penumbra System in Routine Practice: COMPLETE Registry Results . Stroke , 53 (3), 769-778. https://dx.doi.org/10.1161/STROKEAHA.121.034268
2021
Bozhkov, Y., Shawarba, J., Feulner, J., Winter, F., Rampp, S., Hoppe, U.,... Rössler, K. (2021). Prediction of Hearing Preservation in Vestibular Schwannoma Surgery According to Tumor Size and Anatomic Extension . Otolaryngology-Head and Neck Surgery . https://dx.doi.org/10.1177/01945998211012674
Eisenhut, F., Engelhorn, T., Arinrad, S., Brandner, S., Coras, R., Putz, F.,... Schmidt, M. (2021). A Comparison of Single- and Multiparametric MRI Models for Differentiation of Recurrent Glioblastoma from Treatment-Related Change . Diagnostics , 11 (12). https://dx.doi.org/10.3390/diagnostics11122281
Eisenhut, F., Gerner, S., Gölitz, P., Dörfler, A., & Seifert, F. (2021). High-resolution magnetic resonance imaging in isolated, traumatic oculomotor nerve palsy: A case report . Radiology Case Reports , 16 (2), 384-388. https://dx.doi.org/10.1016/j.radcr.2020.12.001
Eisenhut, F., Lang, S., Hölter, P., Wiesmüller, M., Uder, M., Iro, H.,... Taha, L. (2021). Identification of anatomic risk factors for scalar translocation in cochlear implant patients . Zeitschrift für Medizinische Physik . https://dx.doi.org/10.1016/j.zemedi.2021.01.009
Fröhlich, K., Siedler, G., Stoll, S., Macha, K., Kinfe, T.M., Dörfler, A.,... Knott, M. (2021). The anesthetic approach for endovascular recanalization therapy depends on the lesion site in acute ischemic stroke . Neuroradiology . https://dx.doi.org/10.1007/s00234-021-02762-3
German, A., Mennecke, A., Martin, J., Hanspach, J., Liebert, A., Herrler, J.,... Laun, F.B. (2021). Brain tissues have single-voxel signatures in multi-spectral MRI . NeuroImage , 234 . https://dx.doi.org/10.1016/j.neuroimage.2021.117986
Haupenthal, D., Kuramatsu, J., Volbers, B., Sembill, J., Mrochen, A., Balk, S.,... Sprügel, M. (2021). Disability-Adjusted Life-Years Associated with Intracerebral Hemorrhage and Secondary Injury . JAMA Network Open . https://dx.doi.org/10.1001/jamanetworkopen.2021.15859
Herrler, J., Liebig, P., Gumbrecht, R., Ritter, D., Schmitter, S., Maier, A.,... Nagel, A.M. (2021). Fast online-customized (FOCUS) parallel transmission pulses: A combination of universal pulses and individual optimization . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.28643
Herz, K., Mueller, S., Perlman, O., Zaitsev, M., Knutsson, L., Sun, P.Z.,... Zaiss, M. (2021). Pulseq-CEST: Towards multi-site multi-vendor compatibility and reproducibility of CEST experiments using an open-source sequence standard . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.28825
Heynold, E., Zimmermann, M., Hore, N., Buchfelder, M., Dörfler, A., Stadlbauer, A., & Kremenevski, N. (2021). Physiological MRI Biomarkers in the Differentiation Between Glioblastomas and Solitary Brain Metastases . Molecular Imaging and Biology . https://dx.doi.org/10.1007/s11307-021-01604-1
Huhn, K., Linz, P., Pemsel, F., Michalke, B., Seyferth, S., Kopp, C.,... Haase, S. (2021). Skin sodium is increased in male patients with multiple sclerosis and related animal models . Proceedings of the National Academy of Sciences of the United States of America , 118 (28). https://dx.doi.org/10.1073/pnas.2102549118
Lang, S., Hölter, P., Schmidt, M., Strother, C., Kaethner, C., Kowarschik, M., & Dörfler, A. (2021). Artificial intelligence-based 3D angiography for visualization of complex cerebrovascular pathologies . American Journal of Neuroradiology , 42 (10), 1722-1768. https://dx.doi.org/10.3174/ajnr.A7252
Laun, F.B., Martin, J., Reymbaut, A., Schmidt, M., Dörfler, A., Topgaard, D., & Uder, M. (2021). Nonparametric D-R1-R2 distribution MRI of the living human brain .
Liebert, A., Tkotz, K., Herrler, J., Linz, P., Mennecke, A., German, A.,... Nagel, A.M. (2021). Whole-brain quantitative CEST MRI at 7T using parallel transmission methods and B1+ correction . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.28745
Loktyushin, A., Herz, K., Dang, N., Glang, F., Deshmane, A., Weinmüller, S.,... Zaiss, M. (2021). MRzero - Automated discovery of MRI sequences using supervised learning . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.28727
Lücking, H., Birkhold, A., Hölter, P., Lang, S., Gölitz, P., Schmidt, M.,... Dörfler, A. (2021). "Virtual stent" - clinical evaluation and user experience of on-the-fly stent simulation in treatment of cerebral aneurysms . Interventional Neuroradiology . https://dx.doi.org/10.1177/15910199211053131
Macha, K., Hölter, P., Siedler, G., Wang, R., Knott, M., Stoll, S.,... Kallmünzer, B. (2021). IV-Thrombolysis in Ischemic Stroke With Unknown Time of Onset—Safety and Outcomes in Posterior vs. Anterior Circulation Stroke . Frontiers in Neurology , 12 . https://dx.doi.org/10.3389/fneur.2021.692067
Manava, P., Hastreiter, P., Schmieder, R., Jung, S., Fahlbusch, R., Dörfler, A.,... Naraghi, R. (2021). Neurovascular compression in arterial hypertension: Correlation of clinical data to 3d-visualizations of mri-findings . Open Neuroimaging Journal , 14 , 16-27. https://dx.doi.org/10.2174/1874440002114010016
Meixner, C., Eisen, C., Schmitter, S., Müller, M., Herrler, J., Hensel, B.,... Nagel, A.M. (2021). Hybrid B1+-shimming and gradient adaptions for improved pseudo-continuous arterial spin labeling at 7 Tesla . Magnetic Resonance in Medicine . https://dx.doi.org/10.1002/mrm.28982
Mennecke, A., Nagel, A.M., Huhn, K., Linker, R., Schmidt, M., Rothhammer, V.,... Dörfler, A. (2021). Longitudinal Sodium MRI of Multiple Sclerosis Lesions: Is there Added Value of Sodium Inversion Recovery MRI . Journal of Magnetic Resonance Imaging . https://dx.doi.org/10.1002/jmri.27832
Menzler, K., Hamer, H., Mross, P., Rosenow, F., Deichmann, R., Wagner, M.,... Knake, S. (2021). Validation of automatic MRI hippocampal subfield segmentation by histopathological evaluation in patients with temporal lobe epilepsy . Seizure-European Journal of Epilepsy , 87 , 94-102. https://dx.doi.org/10.1016/j.seizure.2021.03.007
Osterloh, J., Heim, C., Siedler, G., Engelhorn, T., Dörfler, A., Schwab, S., & Kallmünzer, B. (2021). Pearls & Oy-sters: Moyamoya Vasculopathy and Its Association With Congenital Heart Disease . Neurology , 96 (23), e2896-e2898. https://dx.doi.org/10.1212/WNL.0000000000012049
Peng, J., Volbers, B., Sprugel, M.I., Hölter, P., Engelhorn, T., Jiang, Y.,... Gerner, S. (2021). Influence of Early Enteral Nutrition on Clinical Outcomes in Neurocritical Care Patients With Intracerebral Hemorrhage . Frontiers in Neurology , 12 . https://dx.doi.org/10.3389/fneur.2021.665791
Rampp, S., Rössler, K., Hamer, H., Illek, M., Buchfelder, M., Dörfler, A.,... Coras, R. (2021). Dysmorphic neurons as cellular source for phase-amplitude coupling in Focal Cortical Dysplasia Type II . Clinical Neurophysiology , 132 (3), 782-792. https://dx.doi.org/10.1016/j.clinph.2021.01.004
Rössler, K., Kasper, B., Tomschik, M., Dörfler, A., Buchfelder, M., & Dorfer, C. (2021). Neurochirurgische Operationsmöglichkeiten bei posteriorer Epilepsie . Zeitschrift für Epileptologie . https://dx.doi.org/10.1007/s10309-020-00386-w
Schenker, H., Tascilar, K., Konerth, L., Sergeeva, M., Prade, J., Strobelt, S.,... Rech, J. (2021). Prediction of response to Certolizumab-Pegol in rheumatoid arthritis (PreCePRA) by functional MRI of the brain – Study protocol for a randomized double-blind controlled study . Contemporary Clinical Trials Communications , 22 . https://dx.doi.org/10.1016/j.conctc.2021.100770
Stadlbauer, A., Heinz, G., Oberndorfer, S., Zimmermann, M., Kinfe, T.M., Buchfelder, M.,... Marhold, F. (2021). Physiological MRI of microvascular architecture, neovascularization activity, and oxygen metabolism facilitate early recurrence detection in patients with IDH-mutant WHO grade 3 glioma . Neuroradiology . https://dx.doi.org/10.1007/s00234-021-02740-9
Stadlbauer, A., Oberndorfer, S., Heinz, G., Zimmermann, M., Kinfe, T.M., Dörfler, A.,... Marhold, F. (2021). Hypoxia and microvascular alterations are early predictors of IDH-mutated anaplastic glioma recurrence . Cancers , 13 (8). https://dx.doi.org/10.3390/cancers13081797
Stock, A., Bozzato, V., Kloska, S., Bozzato, A., Hoppe, U., Hornung, J.,... Struffert, T. (2021). Correction to: Evaluation After Cochlear Implant Surgery: Correlation of Clinical Outcome and Imaging Findings using Flat-detector CT (Clinical Neuroradiology, (2021), 31, 2, (367-372), 10.1007/s00062-020-00922-1) . Clinical Neuroradiology . https://dx.doi.org/10.1007/s00062-021-01074-6
Strauß, C., Rampp, S., Scheller, C., Prell, J., Strauss, C., Dörfler, A., & Engelhorn, T. (2021). Volumetry and Surgical Grading Systems for Vestibular Schwannoma Size Assessment and their Relationship to Postoperative Facial Nerve Function . Journal of Neurological Surgery Part A: Central European Neurosurgery . https://dx.doi.org/10.1055/s-0041-1725951
Vogel, S., Kaltenhaeuser, M., Kim, C., Müller-Voggel, N., Roessler, K., Dörfler, A.,... Rampp, S. (2021). MEG Node Degree Differences in Patients with Focal Epilepsy vs. Controls-Influence of Experimental Conditions . Brain Sciences , 11 (12). https://dx.doi.org/10.3390/brainsci11121590
Volbers, B., Gröger, R., Engelhorn, T., Marsch, A., Macha, K., Schwab, S.,... Kallmünzer, B. (2021). Acute Stroke With Large Vessel Occlusion and Minor Clinical Deficits: Prognostic Factors and Therapeutic Implications . Frontiers in Neurology , 12 . https://dx.doi.org/10.3389/fneur.2021.736795
2020
Eisenhut, F., Schmidt, M., Putz, F., Lettmaier, S., Fröhlich, K., Arinrad, S.,... Dörfler, A. (2020). Classification of primary cerebral lymphoma and glioblastoma featuring dynamic susceptibility contrast and apparent diffusion coefficient . Brain Sciences , 10 (11), 1-10. https://dx.doi.org/10.3390/brainsci10110886
Etminan, N., Dörfler, A., & Steinmetz, H. (2020). Consider Various Therapy Options Reply . Deutsches Ärzteblatt international , 117 (33-34), 563-563. https://dx.doi.org/10.3238/arztebl.2020.0563b
Etminan, N., Dörfler, A., & Steinmetz, H. (2020). Unruptured Intracranial Aneurysms- Pathogenesis and Individualized Management . Deutsches Ärzteblatt international , 117 (14), 235-242. https://dx.doi.org/10.3238/arztebl.2020.0235
Frey, B., Goerig, N., Becker, I., Donaubauer, A.-J., Korn, K., Überla, K.,... Fietkau, R. (2020). Reactivation of HCMV during RT of the brain results in critical illness and early mortality . In RADIOTHERAPY AND ONCOLOGY (pp. S193-S194). CLARE: ELSEVIER IRELAND LTD.
Gerner, S., Hülsbrink, R., Reichl, J., Mrochen, A., Eyüpoglu, I.Y., Brandner, S.,... Huttner, H. (2020). Parenchymatous hematoma in patients with atraumatic subarachnoid hemorrhage: Characteristics, treatment, and clinical outcomes . International Journal of Stroke . https://dx.doi.org/10.1177/1747493020971878
Goerig, N., Frey, B., Korn, K., Fleckenstein, B., Überla, K., Schmidt, M.,... Fietkau, R. (2020). Early Mortality of Brain Cancer Patients and its Connection to Cytomegalovirus Reactivation During Radiochemotherapy . Clinical Cancer Research , 26 (13), 3259-3270. https://dx.doi.org/10.1158/1078-0432.CCR-19-3195
Gölitz, P., Lücking, H., Hölter, P., Knossalla, F., & Dörfler, A. (2020). What is the hemodynamic effect of the Woven EndoBridge? An in vivo quantification using time-density curve analysis . Neuroradiology . https://dx.doi.org/10.1007/s00234-020-02390-3
Horndasch, S., Rösch, J., Kratz, O., Vogel, A., Heinrich, H., Graap, H.,... Forster, C. (2020). Neural mechanisms of perceptive and affective processing of body stimuli in anorexia nervosa – are there developmental effects? Psychiatry Research , 286 . https://dx.doi.org/10.1016/j.psychres.2020.112853
Hölter, P., Mühlen, I., Gölitz, P., Beuscher, V., Schwab, S., & Dörfler, A. (2020). Automated ASPECT scoring in acute ischemic stroke: comparison of three software tools . Neuroradiology . https://dx.doi.org/10.1007/s00234-020-02439-3
Kasper, B., Roessler, K., & Dörfler, A. (2020). Etiological aspects of posterior epilepsies . Zeitschrift für Epileptologie . https://dx.doi.org/10.1007/s10309-020-00376-y
Lücking, H., Dörfler, A., Gölitz, P., Hölter, P., Engelhorn, T., & Lang, S. (2020). Two- to five-year follow-up of 78 patients after treatment with the Flow Redirection Endoluminal Device . Interventional Neuroradiology , 26 (1), 38-44. https://dx.doi.org/10.1177/1591019919878551
Lücking, H., Struffert, T., Gölitz, P., Engelhorn, T., Brandner, S., Kuramatsu, J.,... Dörfler, A. (2020). Stent-Assisted Coiling Using Leo+ Baby Stent: Immediate and Mid-Term Results . Clinical Neuroradiology . https://dx.doi.org/10.1007/s00062-020-00904-3
Macha, K., Hölter, P., Siedler, G., Knott, M., Schwab, S., Dörfler, A.,... Engelhorn, T. (2020). Multimodal CT or MRI for IV thrombolysis in ischemic stroke with unknown time of onset . Neurology , 95 (22), e2954-e2964. https://dx.doi.org/10.1212/WNL.0000000000011059
Manava, P., Naraghi, R., Schmieder, R., Fahlbusch, R., Dörfler, A., Lell, M.M.,... Hastreiter, P. (2020). 3D-Visualization of Neurovascular Compression at the Ventrolateral Medulla in Patients with Arterial Hypertension . Clinical Neuroradiology . https://dx.doi.org/10.1007/s00062-020-00916-z
Mengling, V., Putz, F., Laun, F.B., Perrin, R., Eisenhut, F., Dörfler, A.,... Bert, C. (2020). Evaluation of the influence of susceptibility-induced magnetic field distortions on the precision of contouring intracranial organs at risk for stereotactic radiosurgery . Physics and Imaging in Radiation Oncology , 15 , 91-97. https://dx.doi.org/10.1016/j.phro.2020.08.001
Mennecke, A., & Dörfler, A. (2020). Editorial for: “ΔADC Analysis of the Brain in Idiopathic Normal Pressure Hydrocephalus Before and After Cerebrospinal Fluid Drainage” . Journal of Magnetic Resonance Imaging . https://dx.doi.org/10.1002/jmri.27442
Meyer, E., Morawa, E., Nacak, Y., Rösch, J., Dörfler, A., Forster, C., & Erim, Y. (2020). Insular Cortical Thickness in Patients With Somatoform Pain Disorder: Are There Associations With Symptom Severity and Childhood Trauma? Frontiers in Psychiatry , 11 . https://dx.doi.org/10.3389/fpsyt.2020.497100
Oechtering, T.H., Panagiotopoulos, N., Völker, M., Lohwasser, S., Ellmann, S., Molwitz, I.,... Raspe, M. (2020). Work and Training Conditions of German Residents in Radiology - Results from a Nationwide Survey Conducted by the Young Radiology Forum in the German Roentgen Society . Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren , 192 (5), 458-469. https://dx.doi.org/10.1055/a-1047-1075
Putz, F., Mengling, V., Perrin, R., Masitho, S., Weissmann, T., Roesch, J.,... Cavallaro, A.J. (2020). Magnetic resonance imaging for brain stereotactic radiotherapy - A review of requirements and pitfalls . Strahlentherapie und Onkologie . https://dx.doi.org/10.1007/s00066-020-01604-0
Rech, J., Schenker, H., Tascilar, K., Hagen, M., Kleyer, A., Simon, D.,... Schett, G. (2020). Brain fMRI Predicts Responses to Certolizumab Pegol in RA. an International, Multi-center, Randomized, Double-blind, Placebocontrolled Trial (PreCePRA) . In ARTHRITIS & RHEUMATOLOGY . HOBOKEN: WILEY.
Rech, J., Tascilar, K., Schenker, H., Hagen, M., Sergeeva, M., Selvakumar, M.,... Schett, G. (2020). LONGITUDINAL CHANGE IN THE CENTRAL NERVOUS SYSTEM PAIN RESPONSE AFTER TREATMENT WITH CERTOLIZUMAB OR PLACEBO. A POST-HOC ANALYSIS FROM THE PRECEPRA TRIAL . In ANNALS OF THE RHEUMATIC DISEASES (pp. 77-78). , ELECTR NETWORK: LONDON: BMJ PUBLISHING GROUP.
Rech, J., Tascilar, K., Schenker, H., Sergeeva, M., Selvakumar, M., Konerth, L.,... Schett, G. (2020). PREDICTION OF RESPONSE TO CERTOLIZUMAB PEGOL TREATMENT BY FUNCTIONAL MRI OF THE BRAIN: AN INTERNATIONAL, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL (PRECEPRA) . In ANNALS OF THE RHEUMATIC DISEASES (pp. 952-952). , ELECTR NETWORK: LONDON: BMJ PUBLISHING GROUP.
Regensburger, M., Schlachetzki, J., Klekamp, J., Dörfler, A., & Winkler, J. (2020). Long-term course of anterior spinal cord herniation presenting with an upper motor neuron syndrome: Case report illustrating diagnostic and therapeutic implications . BMC Neurology , 20 (1). https://dx.doi.org/10.1186/s12883-020-01891-1
Rhein, C., Mühle, C., Lenz, B., Richter-Schmidinger, T., Kogias, G., Boix, F.,... Müller, C.P. (2020). Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly . Brain Research Bulletin , 161 , 13-20. https://dx.doi.org/10.1016/j.brainresbull.2020.05.001
Rösch, J., Mennecke, A., Knott, M., Dörfler, A., & Grodzki, D.M. (2020). Quiet FLAIR at 7T MRI . Investigative Radiology , 55 (11), 722-726. https://dx.doi.org/10.1097/RLI.0000000000000694
Rösch, J., Mennecke, A., Knott, M., Hamer, H., Dörfler, A., & Engelhorn, T.M. (2020). T2-sequence with contrast inversion: diagnostic value in the investigation of gray matter heterotopias . NeuroReport , 31 (9), 686-690. https://dx.doi.org/10.1097/WNR.0000000000001463
Röther, J., Busse, O., Berlis, A., Dörfler, A., Groden, C., Hamann, G.,... Nabavi, D. (2020). Erratum zu: Interdisziplinäre neurovaskuläre Netzwerke: eine Standortbestimmung . Der Nervenarzt . https://dx.doi.org/10.1007/s00115-020-01016-6
Röther, J., Busse, O., Berlis, A., Dörfler, A., Groden, C., Hamann, G.,... Nabavi, D. (2020). Interdisziplinäre neurovaskuläre Netzwerke: eine Standortbestimmung . Der Nervenarzt . https://dx.doi.org/10.1007/s00115-020-00991-0
Schenker, H., Rech, J., Tascilar, K., Hagen, M., Schoenau, V., Sergeeva, M.,... Schett, G. (2020). CENTRAL NERVOUS SYSTEM PAIN RESPONSE AND COMPONENTS OF DISEASE ACTIVITY IN RA PATIENTS AFTER TREATMENT WITH CERTOLIZUMAB OR PLACEBO: A POST-HOC ANALYSIS FROM THE PRECEPRA TRIAL . In ANNALS OF THE RHEUMATIC DISEASES (pp. 135-136). , ELECTR NETWORK: LONDON: BMJ PUBLISHING GROUP.
Schmidt, M., Engelhorn, T., Lang, S., Lücking, H., Hölter, P., Fröhlich, K.,... Dörfler, A. (2020). DSC Brain Perfusion Using Advanced Deconvolution Models in the Diagnostic Work-Up of Dementia and Mild Cognitive Impairment: A Semiquantitative Comparison with HMPAO-SPECT-Brain Perfusion . Journal of Clinical Medicine , 9 (6). https://dx.doi.org/10.3390/jcm9061800
Schmidt, M., Knott, M., Engelhorn, T., Larsson, E.M., Nguyen, T., Essig, M.,... Hölter, P. (2020). Standardized acquisition and post-processing of dynamic susceptibility contrast perfusion in patients with brain tumors, cerebrovascular disease and dementia: comparability of post-processing software . British Journal of Radiology , 93 (1105), 20190543-. https://dx.doi.org/10.1259/bjr.20190543
Sembill, J., Castello, J.P., Sprügel, M., Gerner, S., Lücking, H., Dörfler, A.,... Hölter, P. (2020). Multicenter Validation of the max-ICH Score in Intracerebral Hemorrhage . Annals of Neurology . https://dx.doi.org/10.1002/ana.25969
Sembill, J., Kuramatsu, J., Gerner, S., Sprügel, M., Röder, S., Madžar, D.,... Hölter, P. (2020). Hematoma enlargement characteristics in deep versus lobar intracerebral hemorrhage . Annals of Clinical and Translational Neurology . https://dx.doi.org/10.1002/acn3.51001
Stadlbauer, A., Kinfe, T.M., Zimmermann, M., Eyüpoglu, I.Y., Brandner, N., Buchfelder, M.,... Brandner, S. (2020). Association between tissue hypoxia, perfusion restrictions, and microvascular architecture alterations with lesion-induced impairment of neurovascular coupling . Journal of Cerebral Blood Flow and Metabolism . https://dx.doi.org/10.1177/0271678X20947546
Stadlbauer, A., Oberndorfer, S., Zimmermann, M., Renner, B., Buchfelder, M., Heinz, G.,... Roessler, K. (2020). Physiologic MR imaging of the tumor microenvironment revealed switching of metabolic phenotype upon recurrence of glioblastoma in humans . Journal of Cerebral Blood Flow and Metabolism , 40 (3), 528-538. https://dx.doi.org/10.1177/0271678X19827885
Stock, A., Bozzato, V., Kloska, S., Bozzato, A., Hoppe, U., Hornung, J.,... Struffert, T. (2020). Evaluation After Cochlear Implant Surgery: Correlation of Clinical Outcome and Imaging Findings using Flat-detector CT . Clinical Neuroradiology . https://dx.doi.org/10.1007/s00062-020-00922-1
Syben, C., Stimpel, B., Roser, P., Dörfler, A., & Maier, A. (2020). Known Operator Learning enables Constrained Projection Geometry Conversion: Parallel to Cone-beam for Hybrid MR/X-ray Imaging . IEEE Transactions on Medical Imaging , 1-1. https://dx.doi.org/10.1109/TMI.2020.2998179
Volbers, B., Mennecke, A., Kästle, N., Huttner, H., Schwab, S., Schmidt, M.,... Dörfler, A. (2020). Quantitative Corticospinal Tract Assessment in Acute Intracerebral Hemorrhage . Translational Stroke Research . https://dx.doi.org/10.1007/s12975-020-00850-9
Winder, K., Kallmünzer, B., Dörfler, A., Hilz, M.-J., Schwab, S., Seifert, F., & Fröhlich, K. (2020). Neuroanatomic Correlates of Angioedema in stroke patients with thrombolysis . In EUROPEAN JOURNAL OF NEUROLOGY (pp. 378-378). ONLINE: HOBOKEN: WILEY.
Witulla, B., Goerig, N., Putz, F., Frey, B., Engelhorn, T., Dörfler, A.,... Laun, F.B. (2020). On PTV definition for glioblastoma based on fiber tracking of diffusion tensor imaging data . PLoS ONE , 15 (1), e0227146-. https://dx.doi.org/10.1371/journal.pone.0227146
Zimmermann, M., Rössler, K., Kaltenhäuser, M., Grummich, P., Yang, B., Buchfelder, M.,... Stadlbauer, A. (2020). Refined Functional Magnetic Resonance Imaging and Magnetoencephalography Mapping Reveals Reorganization in Language-Relevant Areas of Lesioned Brains . World Neurosurgery . https://dx.doi.org/10.1016/j.wneu.2019.10.014
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The scientific focus of the Department of Neuroradiology is on multimodal imaging, especially in stroke, brain tumors, focal epilepsies, MS and dementia and on the minimally invasive treatment of cerebral aneurysms, vascular malformation, stenosis and acute stroke using state-of-the-art imaging technology including innovative flat-panel imaging and clinically approved ultrahigh-field 7 Tesla MRI.
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