Regarding MedTech research, our main focus is a touchless and burden-free assessment of biomarkers, which are objective and quantifiable, e.g. radar-based detection of heartbeat and breathing as well as AI-applications for both clinical routine data and experimental data as the aforementioned radar-based biomarkers. We underpin our MedTech research with another scientific core competency of our research department: research into ethical, legal, and social aspects and implications. We address social aspects with a strong background in healthcare research and a mixed-methods approach. To study ethical and legal aspects we have established close collaborations with research partners.
Research projects
Radar-based vital parameter assessment: using six-port interferometry we detect biomarkers, e.g. pulse wave, heart sounds, thoraxic excursions by breathing;
As tertiary data we derive heart rate variability from heart rate over time AI-based analyses: using methods based on learning algorithms, e.g. rule mining we analyse structured and unstructured clinical routine data
Experimental data Health App-Research: first health market prototypes for assessment, monitoring and improving health and patient care
Current projects Current projects
Recent publications Recent publications
2024
Kremling, A., Bausewein, C., Klein, C., Nadolny, S., Ostgathe, C., Schildmann, E.,... Schildmann, J. (2024). Terminological Confusion About Sedation in Palliative Care: Results of an International Online Vignette Survey . Journal of palliative medicine , 27 (4), 487-494. https://doi.org/10.1089/jpm.2023.0159
Rosenbruch, J., Eschbach, C., Viehrig, M., Ostgathe, C., & Bausewein, C. (2024). SOP – Respiratory distress in adult palliative care patients SOP – Atemnot bei erwachsenen Palliativpatienten . Die Onkologie . https://doi.org/10.1007/s00761-024-01475-5
2023
Bräunig, J., Mejdani, D., Krauß, D., Grießhammer, S., Richer, R., Schüßler, C.,... Vossiek, M. (2023). Radar-based Recognition of Activities of Daily Living in the Palliative Care Context Using Deep Learning . In 2023 IEEE EMBS International Conference on Biomedical and Health Informatics (BHI) . Pittsburgh, US: IEEE.
Gahr, S., Brunner, S., Heckel, M., & Ostgathe, C. (2023). Are There Entity-Specific Criteria for Initiation of Specialized Palliative Care for Incurable Cancer? A Scoping Review . Zeitschrift für Palliativmedizin . https://dx.doi.org/10.1055/a-2054-1201
Grimminger, S., Heckel, M., Markgraf, M., Peuten, S., Wöhl, M., Gimpel, H.,... Schneider, W. (2023). Palliative care as a digital working world (PALLADiUM) - A mixed-method research protocol . BMC Palliative Care , 22 (1). https://doi.org/10.1186/s12904-023-01173-w
Hense, J., Przyborek, M., Rosenbruch, J., Ostgathe, C., & Wolf, C. (2023). SOP – Subkutane Medikamentengabe und Infusionen in der erwachsenen Palliativmedizin Version II . Die Onkologie . https://doi.org/10.1007/s00761-023-01409-7
Kauzner, S., Heckel, M., Ostgathe, C., Schneider, M., Bausewein, C., Schildmann, E.,... Klein, C. (2023). Documentation of Sedation in Palliative Care: A Scoping Review of Requirements, Recommendations, and Templates . Journal of Palliative Medicine . https://doi.org/10.1089/jpm.2022.0476
Klein, C., & Ostgathe, C. (2023). Aktuelle Empfehlungen für die gezielte Sedierung am Lebensende . MMW Fortschritte der Medizin , 165 (21-22), 58-61. https://dx.doi.org/10.1007/s15006-023-3146-y
Klein, C., Voss, R., Ostgathe, C., & Schildmann, J.A. (2023). Sedation in Palliative Care. Deutsches Ärzteblatt international , 120 (14), 235-242. https://dx.doi.org/10.3238/arztebl.m2023.0034
Lu, H., Wenzel, M., Steigleder, T., Klinger, I., Ostgathe, C., & Koelpin, A. (2023). Contactless In-Bed Movement in Various Scales Classification with CW Radar . In 20th European Radar Conference, EuRAD 2023 (pp. 306-309). Berlin, DE: Institute of Electrical and Electronics Engineers Inc..
Ostgathe, C., Bausewein, C., Schildmann, E., Bazata, J., Handtke, V., Heckel, M.,... Schildmann, J. (2023). Expert-approved best practice recommendations on the use of sedative drugs and intentional sedation in specialist palliative care (SedPall) . BMC Palliative Care , 22 (1). https://doi.org/10.1186/s12904-023-01243-z
Ostgathe, C., & Jäger, C. (2023). Current legal aspects of physician-assisted suicide in Germany Aktuelles zum ärztlich assistierten Suizid in Deutschland . MMW Fortschritte der Medizin , 165 (17), 32-35. https://doi.org/10.1007/s15006-023-2881-4
Ott, T., Heckel, M., Öhl, N., Steigleder, T., Albrecht, N., Ostgathe, C., & Dabrock, P. (2023). Palliative Care and new technologies. The use of smart sensor technologies and its impact on the Total Care principle . BMC Palliative Care . https://doi.org/10.1186/s12904-023-01174-9
2022
Allner, M., Gostian, M., Rupp, R., Allner, C., Mantsopoulos, K., Ostgathe, C.,... Balk, M. (2022). Advance directives in patients with head and neck cancer - status quo and factors influencing their creation . BMC Palliative Care , 21 (1). https://doi.org/10.1186/s12904-022-00932-5
Biersching, T., Schweda, A., Oechsle, K., Nauck, F., Rosenbruch, J., Schuler, U.,... Tewes, M. (2022). The OUTREACH study: oncologists of German university hospitals in rotation on a palliative care unit-evaluation of attitude and competence in palliative care and hospice . Journal of Cancer Research and Clinical Oncology . https://doi.org/10.1007/s00432-022-04131-w
Brunner, S., Heckel, M., Zenz, D., Ostgathe, C., & Gahr, S. (2022). Health- and disease-related data of inpatients in palliative care units of the Comprehensive Cancer Centers and other hospitals in comparison-Data from the Hospice and Palliative Care Register . Wiener Medizinische Wochenschrift . https://dx.doi.org/10.1007/s10354-021-00910-1
Fidorra, J., Nissen, M., Abdullahi Yari, I., Ostgathe, C., Steigleder, T., & Eskofier, B. (2022). Concept of a Simple Reaction Test for eHealth-Based Opioid Response Assessment in Palliative Care .
Klinger, I., Heckel, M., Shahda, S., Kriesen, U., Schneider, C., Kurkowski, S.,... Ostgathe, C. (2022). COVID-19: Challenges and solutions for the provision of care to seriously ill and dying people and their relatives during SARS-CoV-2 pandemic - perspectives of pandemic response team members: A qualitative study on the basis of expert interviews (part of PallPan) . Palliative Medicine . https://dx.doi.org/10.1177/02692163221099114
Klinger, I., Heckel, M., Shahda, S., Krisen, U., Stellmacher, S., Kurkowski, S.,... Ostgathe, C. (2022). COVID-19 pandemic response teams: organization, competencies, and challenges-understanding and using structural realities . Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz . https://doi.org/10.1007/s00103-022-03542-x
Kremling, A., Bausewein, C., Klein, C., Schildmann, E., Ostgathe, C., Ziegler, K., & Schildmann, J. (2022). Intentional Sedation as a Means to Ease Suffering: A Systematically Constructed Terminology for Sedation in Palliative Care . Journal of Palliative Medicine . https://dx.doi.org/10.1089/jpm.2021.0428
Kurkowski, S., Heckel, M., Pfaller, L., Peters, J., Bazata, J., Schildmann, E., & Ostgathe, C. (2022). Correction: Possible age-related differences in healthcare professionals’ perspectives on younger and older patients’ autonomy and decision-making in the context of sedation in specialised palliative care: exploratory secondary qualitative content and linguistic conversation analysis of interviews with healthcare professionals (BMC Palliative Care, (2022), 21, 1, (71), 10.1186/s12904-022-00963-y) . BMC Palliative Care , 21 (1). https://doi.org/10.1186/s12904-022-00990-9
Kurkowski, S., Heckel, M., Pfaller, L., Peters, J., Jeremias, B., Eva, S., & Ostgathe, C. (2022). Possible age-related differences in healthcare professionals’ perspectives on younger and older patients’ autonomy and decision-making in the context of sedation in specialised palliative care: exploratory secondary qualitative content and linguistic conversation analysis of interviews with healthcare professionals . BMC Palliative Care , 21 . https://dx.doi.org/10.1186/s12904-022-00963-y
Kurkowski, S., Ziegler, K., Jäger, C., Torres Cavazos, J., Heckel, M., Klein, C., & Ostgathe, C. (2022). More Barriers than Bridges - Research in Times of the GDPR . Zeitschrift für Palliativmedizin , 23 (02), 86-89. https://doi.org/10.1055/a-1744-5270
Mueller, E., Mueller, M.J., Boehlke, C., Ramsenthaler, C., Jaeger, H., Schaefer, H.,... Becker, G. (2022). Development of a screening tool for the need of specialist palliative care in oncologic inpatients: study protocol for the ScreeningPALL Study . BMJ Open , 12 (9). https://doi.org/10.1136/bmjopen-2021-059598
Ostgathe, C., Stachura, P., Heckel, M., Brunner, S., Gahr, S., Hofmann, S.,... Klein, C. (2022). SOP - Management of multiresistent Pathogens in the Palliative Care Unit . Die Onkologie . https://doi.org/10.1007/s00761-022-01201-z
Payne, S., Harding, A., Williams, T., Ling, J., & Ostgathe, C. (2022). Revised recommendations on standards and norms for palliative care in Europe from the European Association for Palliative Care (EAPC): A Delphi study . Palliative Medicine . https://dx.doi.org/10.1177/02692163221074547
Peters, J., Dykes, N., Heckel, M., Ostgathe, C., & Habermann, M. (2022). Präsentation von Palliativstationen und SAPV-Teams im Internet - eine korpusbasierte Metaanalyse von Webseiten . Zeitschrift für Palliativmedizin , 23 , 46-53. https://dx.doi.org/10.1055/a-1689-7524
Peters, J., Rabenstein, U., Heckel, M., Breindl, E., & Ostgathe, C. (2022). Palliativversorgung in Zeiten der COVID-19-Pandemie: Wandelt sich die öffentliche Wahrnehmung? (Abstract) . Zeitschrift für Palliativmedizin , 23 (5), e9.
2021
Allner, M., Gostian, M., Balk, M., Rupp, R., Hecht, M., Ostgathe, C.,... Gostian, A.-O. (2021). Precautionary documents in patients with head and neck cancer - status quo and factors influencing their creation . In ORAL ONCOLOGY . AMSTERDAM: ELSEVIER.
Bender-Säbelkampf, S., Heckel, M., Ostgathe, C., Berking, C., & Heppt, M. (2021). PaM - Development and Validation of a palliative medical Integration Model for Melanoma . In JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT (pp. 13-14). HOBOKEN: WILEY.
Fiedler, G., Drinkmann, A., Hauth, I., Lenz, P., Letsch, A., Lewitzka, U.,... Wolfersdorf, M. (2021). ARD shows "GOTT": Open Letter from Palliative Medicine & Suicide Prevention to Ferdinand von Schirach . Zeitschrift für Palliativmedizin , 22 (01), 20-22.
Haas, O., Lopera Gonzalez, L.I., Hofmann, S., Ostgathe, C., Maier, A., Rothgang, E.,... Steigleder, T. (2021). Predicting Anxiety in Routine Palliative Care Using Bayesian-Inspired Association Rule Mining . Frontiers in Digital Health , 3 . https://dx.doi.org/10.3389/fdgth.2021.724049
Kamal Mallick, M., Biser, S., Haridas, A., Umesh, V., Toensing, O., Abdullahi, I.,... Steigleder, T. (2021). Improving Dyspnoea Symptom Control of Patients in Palliative Care Using a Smart Patch-A Proof of Concept Study . Frontiers in Digital Health , 3 (765867). https://dx.doi.org/10.3389/fdgth.2021.765867
Lehmann, E., Hodiamont, F., Landmesser, M., Knobloch, C., Nauck, F., Ostgathe, C.,... Bausewein, C. (2021). Adaptation of the Australian Palliative Care Phase concept to the German palliative care context: a mixed-methods approach using cognitive interviews and cross-sectional data . BMC Palliative Care , 20 (1). https://doi.org/10.1186/s12904-021-00825-z
Oechsle, K., Theissen, T., Heckel, M., Schwenzitzki, L., Ullrich, A., & Ostgathe, C. (2021). Support for and involvement of family caregivers in Comprehensive Cancer Center - an Assessment of the Palliative Care Working Group within the network of Comprehensive Cancer Center funded by the German Cancer Aid . Deutsche Medizinische Wochenschrift . https://doi.org/10.1055/a-1543-2511
Ostgathe, C. (2021). EAPC 2020 Research Congress: From Palermo to virtual . Zeitschrift für Palliativmedizin , 22 (01), 5-6.
Shi, K., Steigleder, T., Schellenberger, S., Michler, F., Malessa, A., Lurz, F.,... Kölpin, A. (2021). Contactless analysis of heart rate variability during cold pressor test using radar interferometry and bidirectional LSTM networks . Scientific Reports , 11 (1). https://dx.doi.org/10.1038/s41598-021-81101-1
Tewes, M., Baumann, F., Teufel, M., & Ostgathe, C. (2021). Symptoms During Outpatient Cancer Treatment and Options for their Management . Deutsches Ärzteblatt international , 118 (17), 291-+. https://dx.doi.org/10.3238/arztebl.m2021.0028
2020
Berendt, J., Ostgathe, C., Simon, S.T., Tewes, M., Schlieper, D., Schallenburger, M.,... Neukirchen, M. (2020). Zusammenarbeit von Intensivmedizin und Palliativmedizin: Eine Bestandsaufnahme an den deutschen onkologischen Spitzenzentren . Medizinische Klinik - Intensivmedizin und Notfallmedizin . https://dx.doi.org/10.1007/s00063-020-00712-0
Harding, R., Snyman, L., Ostgathe, C., Odell, S., & Gwyther, L. (2020). The ethical imperative to relieve suffering for people with tuberculosis by ensuring access to palliative care . International Journal of Tuberculosis and Lung Disease , 24 (5), 3-8. https://dx.doi.org/10.5588/ijtld.18.0240
Heckel, M., Illig, A., Brunner, S., & Ostgathe, C. (2020). Evaluating the implementation of national recommendations on multidrug-resistant bacterial microorganisms in end-of-life care . Zeitschrift für Evidenz, Fortbildung und Qualitat im Gesundheitswesen . https://dx.doi.org/10.1016/j.zefq.2020.10.005
Heckel, M., Meesters, S., Schildmann, E., & Ostgathe, C. (2020). Patient*innen gestalten Forschung in der Palliativmedizin mit . Zeitschrift für Evidenz, Fortbildung und Qualitat im Gesundheitswesen . https://dx.doi.org/10.1016/j.zefq.2020.10.002
Heckel, M., Vogt, A.R., Stiel, S., Radon, J., Kurkowski, S., Goebel, S.,... Weber, M. (2020). The quality of care of the dying in hospital—next-of-kin perspectives . Supportive Care in Cancer . https://doi.org/10.1007/s00520-020-05465-2
Klein, C., Wittmann, C., Wendt, K.N., Ostgathe, C., & Stiel, S. (2020). Erratum to: Palliative sedation: Development and consensus of a German language documentation template (Der Anaesthesist, (2018), 67, 7, (504-511), 10.1007/s00101-018-0451-4) Erratum zu: Palliative Sedierung: Entwicklung und Konsentierung einer deutschsprachigen Dokumentationsvorlage (Der Anaesthesist, (2018), 67, 7, (504-511), 10.1007/s00101-018-0451-4) . Anaesthesist . https://doi.org/10.1007/s00101-020-00729-2
Kurkowski, S., Radon, J., Vogt, A.R., Weber, M., Stiel, S., Ostgathe, C., & Heckel, M. (2020). Hospital end-of-life care: Families' free-text notes . BMJ Supportive & Palliative Care . https://dx.doi.org/10.1136/bmjspcare-2020-00239
Lödel, S., Ostgathe, C., Heckel, M., Oechsle, K., & Gahr, S. (2020). Standard Operating Procedures (SOPs) for Palliative Care in German Comprehensive Cancer Centers - An evaluation of the implementation status . BMC Palliative Care , 19 (1). https://doi.org/10.1186/s12904-020-00565-6
Ostgathe, C. (2020). Patientenverfügung 2.0 . Anaesthesist , 69 (2), 75-77. https://dx.doi.org/10.1007/s00101-019-00723-3
Peters, J., Dykes, N., Ostgathe, C., Habermann, M., & Heckel, M. (2020). Kompetenzdarstellung, Patientennähe und Argumentationsstrategien von Internetangeboten deutscher Hospize, Palliativstationen und SAPV-Teams-eine korpusbasierte Meta-Analyse . Zeitschrift für Palliativmedizin , 21 (5), e34.
Schellenberger, S., Shi, K., Steigleder, T., Malessa, A., Michler, F., Hameyer, L.,... Kölpin, A. (2020). A dataset of clinically recorded radar vital signs with synchronised reference sensor signals . Scientific Data . https://dx.doi.org/10.1038/s41597-020-00629-5
Shi, K., Schellenberger, S., Will, C., Steigleder, T., Michler, F., Fuchs, J.,... Koelpin, A. (2020). A dataset of radar-recorded heart sounds and vital signs including synchronised reference sensor signals. Scientific Data , 7 (1). https://doi.org/10.1038/s41597-020-0390-1
Sternemann, U., Suchantke, I., Schmidt, K.-G., Höfner, P., Wagner, D., Ollenschläger, M.,... Steigleder, T. (2020, August). Entwicklung einer Applikation zum Home-Monitoring des Gesundheitszustandes von Palliativpatienten - eine Proof-of-Concept-Studie .
Vogt, A., Stiel, S., Heckel, M., Goebel, S., Mai, S.S., Seifert, A.,... Weber, M. (2020). Assessment of the quality of end-of-life care: translation and validation of the German version of the "Care of the Dying Evaluation" (CODE-GER) - a questionnaire for bereaved relatives . Health and Quality of Life Outcomes , 18 (1), 311-. https://dx.doi.org/10.1186/s12955-020-01473-2
Related Research Fields
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Regarding MedTech research, our main focus is a touchless and burden-free assessment of biomarkers, which are objective and quantifiable, e.g. radar-based detection of heartbeat and breathing as well as AI-applications for both clinical routine data and experimental data as the aforementioned radar-based biomarkers. We underpin our MedTech research with another scientific core competency of our research department: research into ethical, legal, and social aspects and implications. We address social aspects with a strong background in healthcare research and a mixed-methods approach. To study ethical and legal aspects we have established close collaborations with research partners.
Research projects
Current projects
Empathokinästhetische Messung und Bewegungsmustererkennung als Biomarker für Gesundheitszustand
(Third Party Funds Group – Sub project)
Term: 1. July 2021 - 30. June 2025
Funding source: DFG / Sonderforschungsbereich (SFB)
URL: https://www.empkins.de/
D05 erforscht bei Palliativpatienten für Gesundheitszustand, Befinden und Prognose erstmals Be-wegungen als Biomarker, d. h. objektivierbare, messbare und quantifizierbare Parameter, die eine diagnostische und prädiktive Bedeutung haben. Diese Biomarker werden in Labor und Living Lab der Palliativstation mit Patientinnen untersucht. Berührungslose Sensorik erlaubt erstmals einen wissenschaftlichen Zugang zur letzten Lebensphase. Ebenso erforscht D05 sozialwissenschaftliche Herausforderungen medizintechnologischer Innovationen in der Palliativmedizin prototypisch für alle Gesundheitsbereiche.
Entwicklung und Machbarkeitsprüfung einer multimodalen Intervention für den Gebrauch sedierender Medikamente in der spezialisierten Palliativversorgung
(Third Party Funds Group – Overall project)
Funding source: Bundesministerium für Bildung und Forschung (BMBF)
URL: https://www.palliativmedizin.uk-erlangen.de/forschung/versorgungsforschung/forschungsprojekte/isedpall/
Recent publications
2024
2023
2022
2021
2020
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