Prof. Dr. Tobias Bäuerle

2023

• Jarraya, M., Roemer, F., Bäuerle, T., Kogan, F., & Guermazi, A. (2023). PET Imaging in Osteoarthritis. PET Clinics, 18(1), 21-29. https://dx.doi.org/10.1016/j.cpet.2022.09.002

2022

• An, R., Strissel, P., Al-Abboodi, M., Robering, J.W., Reakasame, S., Eckstein, M.,... Kengelbach-Weigand, A. (2022). An Innovative Arteriovenous (AV) Loop Breast Cancer Model Tailored for Cancer Research. Bioengineering, 9(7). https://dx.doi.org/10.3390/bioengineering9070280
• Blumenberg, V., Busch, G., Baumann, S., Jitschin, R., Winkelmann, M., Hellwig, K.,... Subklewe, M. (2022). Early Expansion of CD19.CAR-T Cells in vivo identify the Patients at Risk for the Treatment Failure in diffuse large B-Cell Lymphoma. In ONCOLOGY RESEARCH AND TREATMENT (pp. 253-253). BASEL: KARGER.
• Bueno-Fortes, S., Muenzner, J.K., Berral-Gonzalez, A., Hampel, C., Lindner, P., Berninger, A.,... Schneider-Stock, R. (2022). A gene signature derived from the loss of cdkn1a (P21) is associated with CMS4 colorectal cancer. Cancers, 14(1). https://dx.doi.org/10.3390/cancers14010136
• Eiblwieser, J., Krumbholz, M., Semper, S., Frey, B., Nagel, L., Bäuerle, T., & Metzler, M. (2022). CtDNA release mechanisms in a therapeutic Ewing Sarcoma mouse model. In KLINISCHE PADIATRIE (pp. 178-178). STUTTGART: GEORG THIEME VERLAG KG.
• Gregoric, G., Gaculenko, A., Nagel, L., Popp, V., Maschauer, S., Prante, O.,... Bäuerle, T. (2022). Non-Invasive Characterization of Experimental Bone Metastasis in Obesity Using Multiparametric MRI and PET/CT. Cancers, 14(10). https://dx.doi.org/10.3390/cancers14102482
• Kalinichenko, L., Mühle, C., Jia, T., Anderheiden, F., Datz, M., Eberle, A.-L.,... Müller, C.P. (2022). Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males. Cerebral Cortex. https://dx.doi.org/10.1093/cercor/bhac106
• Marino, S., Hannemann, N., Bishop, R.T., Zeng, F., Carrasco, G., Meurisse, S.,... Idris, A.I. (2022). Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis. Biochemical Pharmacology, 195. https://dx.doi.org/10.1016/j.bcp.2021.114869
• Masitho, S., Putz, F., Mengling, V., Reißig, L., Voigt, R., Bäuerle, T.,... Bert, C. (2022). Accuracy of MRI-CT registration in brain stereotactic radiotherapy: Impact of MRI acquisition setup and registration method. Zeitschrift für Medizinische Physik. https://dx.doi.org/10.1016/j.zemedi.2022.04.004
• Royzman, D., Andreev, D., Stich, L., Peckert, K., Wild, A., Zinser, E.,... Steinkasserer, A. (2022). The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis. Frontiers in Immunology, 13. https://dx.doi.org/10.3389/fimmu.2022.936995
• Steiner, D., Reinhardt, L., Fischer, L., Popp, V., Körner, C., Geppert, C.,... Arkudas, A. (2022). Impact of Endothelial Progenitor Cells in the Vascularization of Osteogenic Scaffolds. Cells, 11(6). https://dx.doi.org/10.3390/cells11060926
• Treutlein, C., Schmidkonz, C., Tascilar, K., Chenguiti Fakhouri, S., Dees, C., Györfi, A.-H.,... Bergmann, C. (2022, June). ASSESSMENT OF SYSTEMIC SCLEROSIS RELATED MYOCARDIAL FIBROSIS BY 68GA-FAPI-04 PET/CT. Poster presentation.
• Wennmann, M., Goldschmidt, H., Mosebach, J., Hielscher, T., Bäuerle, T., Komljenovic, D.,... Hillengass, J. (2022). Whole-body magnetic resonance imaging plus serological follow-up for early identification of progression in smouldering myeloma patients to prevent development of end-organ damage. British Journal of Haematology. https://dx.doi.org/10.1111/bjh.18232
• Zeun, J., Neubeck, S., Lang, V., Flamann, C., Nagel, L., Kunert, T.,... Kremer, A. (2022). HLA-DO: a possible switch between GvHD and GvL effect. In EUROPEAN JOURNAL OF IMMUNOLOGY (pp. 411-411). HOBOKEN: WILEY.

2021

• Bergmann, C., Distler, J., Treutlein, C., Tascilar, K., Müller, A., Atzinger, A.,... Schmidkonz, C. (2021). 68GA-FAPI-04 PET/CT STUDY EXTENSION FOR THE ASSESSMENT OF FIBROBLAST ACTIVATION AND RISK EVALUATION IN SYSTEMIC SCLEROSIS-RELATED INTERSTITIAL LUNG DISEASE. In ANNALS OF THE RHEUMATIC DISEASES (pp. 165-166). LONDON: BMJ PUBLISHING GROUP.
• Bergmann, C., Distler, J., Treutlein, C., Tascilar, K., Müller, A., Atzinger, A.,... Schmidkonz, C. (2021). 68Ga-FAPI-04 PET-CT for molecular assessment of fibroblast activation and risk evaluation in systemic sclerosis-associated interstitial lung disease: a single-centre, pilot study. The Lancet Rheumatology. https://dx.doi.org/10.1016/S2665-9913(20)30421-5
• Bäuerle, T., Gupta, S., Zheng, S., Seyler, L., Leporati, A., Marosfoi, M.,... Bogdanov, A. (2021). Multimodal Bone Metastasis-associated Epidermal Growth Factor Receptor Imaging in an Orthotopic Rat Model. Radiology: Imaging Cancer, 3(4). https://dx.doi.org/10.1148/rycan.2021200069
• Bäuerle, T., & Roemer, F. (2021). Dynamic contrast-enhanced MRI for assessment of subchondral bone marrow vascularization in an experimental osteoarthritis model: a major step towards clinical translation? Osteoarthritis and Cartilage. https://dx.doi.org/10.1016/j.joca.2021.03.001
• Ellmann, S., & Bäuerle, T. (2021). Editorial for "Deep Learning Assisted Diagnosis of Musculoskeletal Tumors Based Upon Contrast-Enhanced Magnetic Resonance Imaging". Journal of Magnetic Resonance Imaging. https://dx.doi.org/10.1002/jmri.28039
• Friščić, J., Böttcher, M., Reinwald, C., Bruns, H., Wirth, B., Popp, S.,... Hoffmann, M. (2021). The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. Immunity. https://dx.doi.org/10.1016/j.immuni.2021.03.003
• Gaculenko, A., Gregoric, G., Popp, V., Seyler, L., Ringer, M., Kachler, K.,... Bozec, A. (2021). Systemic PPAR gamma Antagonism Reduces Metastatic Tumor Progression in Adipocyte-Rich Bone in Excess Weight Male Rodents. Journal of Bone and Mineral Research. https://dx.doi.org/10.1002/jbmr.4422
• Hartmann, B., Müller, M., Seyler, L., Bäuerle, T., Wilferth, T., Avdievitch, N.,... Nagel, A.M. (2021). Feasibility of deuterium magnetic resonance spectroscopy of 3-O-Methylglucose at 7 Tesla. PLoS ONE, 16(6 June). https://dx.doi.org/10.1371/journal.pone.0252935
• Heinen, H., Seyler, L., Popp, V., Hellwig, K., Bozec, A., Uder, M.,... Bäuerle, T. (2021). Morphological, functional, and molecular assessment of breast cancer bone metastases by experimental ultrasound techniques compared with magnetic resonance imaging and histological analysis. Bone, 144. https://dx.doi.org/10.1016/j.bone.2020.115821
• Hellwig, K., Ellmann, S., Eckstein, M., Wiesmüller, M., Rutzner, S., Semrau, S.,... Gostian, A.-O. (2021). Predictive Value of Multiparametric MRI for Response to Single-Cycle Induction Chemo-Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma. Frontiers in Oncology, 11. https://dx.doi.org/10.3389/fonc.2021.734872
• Huhn, K., Linz, P., Pemsel, F., Michalke, B., Seyferth, S., Kopp, C.,... Haase, S. (2021). Skin sodium is increased in male patients with multiple sclerosis and related animal models. Proceedings of the National Academy of Sciences of the United States of America, 118(28). https://dx.doi.org/10.1073/pnas.2102549118
• Kengelbach-Weigand, A., Thielen, C., Bäuerle, T., Götzl, R., Gerber, T., Körner, C.,... Boos, A. (2021). Personalized medicine for reconstruction of critical-size bone defects – a translational approach with customizable vascularized bone tissue. npj Regenerative Medicine, 6(1). https://dx.doi.org/10.1038/s41536-021-00158-8
• Krumbholz, M., Eiblwieser, J., Ranft, A., Zierk, J., Schmidkonz, C., Stuetz, A.M.,... Metzler, M. (2021). Quantification of translocation-specific ctDNA provides an integrating parameter for early assessment of treatment response and risk stratification in ewing sarcoma. Clinical Cancer Research, 27(21), 5922-5930. https://dx.doi.org/10.1158/1078-0432.CCR-21-1324
• Oprea-Lager, D.E., Cysouw, M.C., Boellaard, R., Deroose, C.M., de Geus-Oei, L.F., Lopci, E.,... Lecouvet, F.E. (2021). Bone Metastases Are Measurable: The Role of Whole-Body MRI and Positron Emission Tomography. Frontiers in Oncology, 11. https://dx.doi.org/10.3389/fonc.2021.772530
• Schmidkonz, C., Distler, J., Treutlein, C., Atzinger, A., Prante, O., Ritt, P.,... Bergmann, C. (2021). Ga-68-FAPI-04 PET/CT for molecular assessment of fibroblast activation and risk evaluation in systemic sclerosis-related interstitial lung disease. European Journal of Nuclear Medicine and Molecular Imaging, S158-S159.
• Schmidkonz, C., Rauber, S., Atzinger, A., Götz, T.I., Soare, A., Cordes, M.,... Ramming, A. (2021). Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging. European Journal of Nuclear Medicine and Molecular Imaging, S125-S126. https://dx.doi.org/10.1055/s-0041-1726701
• Schroeder, A., Seyler, L., Hofmann, E., Gölz, L., Jantsch, J., Proff, P.,... Kirschneck, C. (2021). Administration of a VEGFR-2-specific MRI contrast agent to assess orthodontic tooth movement A pilot study. Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie. https://dx.doi.org/10.1007/s00056-021-00326-x
• Wild, M., Kicuntod, J., Seyler, L., Wangen, C., Bertzbach, L.D., Conradie, A.M.,... Marschall, M. (2021). Combinatorial drug treatments reveal promising anticytomegaloviral profiles for clinically relevant pharmaceutical kinase inhibitors (PKIs). International Journal of Molecular Sciences, 22(2), 1-20. https://dx.doi.org/10.3390/ijms22020575

2020

• Bobinger, T., Bäuerle, T., Seyler, L., von Hörsten, S., Schwab, S., Huttner, H., & Manaenko, A. (2020). A Sphingosine-1-Phosphate Receptor Modulator Attenuated Secondary Brain Injury and Improved Neurological Functions of Mice after ICH. Oxidative Medicine and Cellular Longevity, 2020. https://dx.doi.org/10.1155/2020/3214350
• Bäuerle, T., Saake, M., & Uder, M. (2020). Gadolinium-based contrast agents: What we learned from acute adverse events, nephrogenic systemic fibrosis and brain retention. Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. https://dx.doi.org/10.1055/a-1328-3177
• Ellmann, S., Schlicht, M., Dietzel, M., Janka, R.M., Hammon, M., Saake, M.,... Bäuerle, T. (2020). Computer-aided diagnosis in multiparametric mri of the prostate: An open-access online tool for lesion classification with high accuracy. Cancers, 12(9), 1-15. https://dx.doi.org/10.3390/cancers12092366
• Ellmann, S., Seyler, L., Gillmann, C., Popp, V., Treutlein, C., Bozec, A.,... Bäuerle, T. (2020). Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model. Journal of Visualized Experiments, 162. https://dx.doi.org/10.3791/61235
• Ellmann, S., Wenkel, E., Dietzel, M., Bielowski, C., Hammon, M., Janka, R.M.,... Vesal, S. (2020). Implementation of machine learning into clinical breast MRI: Potential for objective and accurate decision-making in suspicious breast masses. PLoS ONE, 1-15, 1-15. https://dx.doi.org/10.1371/journal.pone.0228446
• Friedberger, A., Figueiredo, C., Bäuerle, T., Schett, G., & Engelke, K. (2020). A new method for quantitative assessment of hand muscle volume and fat in magnetic resonance images. BMC Rheumatology, 4(1). https://dx.doi.org/10.1186/s41927-020-00170-3
• Friedberger, A., Figueiredo, C., Grimm, A., Oliveira, I., Bäuerle, T., Rech, J.,... Engelke, K. (2020). Quantification of hand muscle volume and composition in patients with rheumatoid arthritis, psoriatic arthritis and psoriasis. BMC Musculoskeletal Disorders, 21(1). https://dx.doi.org/10.1186/s12891-020-03194-5
• Habermeyer, J., Boyken, J., Harrer, J., Canneva, F., Ratz, V., Moceri, S.,... von Hörsten, S. (2020). Comprehensive phenotyping revealed transient startle response reduction and histopathological gadolinium localization to perineuronal nets after gadodiamide administration in rats. Scientific Reports, 10(1). https://dx.doi.org/10.1038/s41598-020-79374-z
• Häge, S., Sonntag, E., Borst, E.M., Tannig, P., Seyler, L., Bäuerle, T.,... Marschall, M. (2020). Patterns of autologous and nonautologous interactions between core nuclear egress complex (NEC) proteins of α‐, β‐ and γ‐herpesviruses. Viruses, 12(3). https://dx.doi.org/10.3390/v12030303
• Korn, M., Schmitt, H., Angermüller, S., Chambers, D., Seeling, M., Lux, U.,... Nitschke, L. (2020). Siglec-15 on osteoclasts is crucial for bone erosion in serum-Transfer arthritis. Journal of Immunology, 205(10), 2595-2605. https://dx.doi.org/10.4049/jimmunol.2000472
• Kuhbandner, K., Hoffmann, A., Alvarado, M.N., Seyler, L., Bäuerle, T., Winkler, J., & Linker, R. (2020). alpha-Synuclein: a Modulator During Inflammatory CNS Demyelination. Journal of Molecular Neuroscience. https://dx.doi.org/10.1007/s12031-020-01498-8
• Lambrecht, V., Hanspach, J., Hoffmann, A., Seyler, L., Mennecke, A., Straub, S.,... Laun, F.B. (2020). Quantitative susceptibility mapping depicts severe myelin deficit and iron deposition in a transgenic model of multiple system atrophy. Experimental Neurology, 329. https://dx.doi.org/10.1016/j.expneurol.2020.113314
• Neri, E., Gabelloni, M., Bäuerle, T., Beets-Tan, R., Caruso, D., D’Anastasi, M.,... Laghi, A. (2020). Involvement of radiologists in oncologic multidisciplinary team meetings: an international survey by the European Society of Oncologic Imaging. European Radiology. https://dx.doi.org/10.1007/s00330-020-07178-w
• Proff, P., Schroeder, A., Seyler, L., Wolf, F., Korkmaz, Y., Bäuerle, T.,... Kirschneck, C. (2020). Local Vascularization during Orthodontic Tooth Movement in a Split Mouth Rat Model - A MRI Study. Biomedicines, 8(12). https://dx.doi.org/10.3390/biomedicines8120632
• Putz, F., Mengling, V., Masitho, S., Perrin, R., Roesch, J., Weissmann, T.,... Bert, C. (2020). Does the Planning MRI for cranial Stereotaxy have to be performed in the Irradiation Position? An Examination of Brain Tissue Deformations between MR Imaging in diagnostic and Radiation Positions. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S200-S201). Weisbaden, DE: HEIDELBERG: SPRINGER HEIDELBERG.
• Putz, F., Mengling, V., Perrin, R., Masitho, S., Weissmann, T., Roesch, J.,... Cavallaro, A.J. (2020). Magnetic resonance imaging for brain stereotactic radiotherapy - A review of requirements and pitfalls. Strahlentherapie und Onkologie. https://dx.doi.org/10.1007/s00066-020-01604-0
• Roemer, F., Treutlein, C., Guermazi, A., Nagel, A.M., Schett, G., Uder, M., & Bäuerle, T. (2020). ASSESSMENT OF KNEE JOINT SYNOVITIS AT ULTRA-HIGH FIELD (7T) MRI: A MULTI-DIMENSIONAL APPROACH USING CONTRAST-ENHANCED AND NON-ENHANCED SEQUENCES. In OSTEOARTHRITIS AND CARTILAGE (pp. S297-S297). Vienna, AT: OXFORD: ELSEVIER SCI LTD.
• Schmidkonz, C., Atzinger, A., Götz, T., Beck, M., Ritt, P., Prante, O.,... Cordes, M. (2020). 99mTc-MIP-1404 SPECT/CT for Patients With Metastatic Prostate Cancer: Interobserver and Intraobserver Variability in Treatment-Related Longitudinal Tracer Uptake Assessments of Prostate-Specific Membrane Antigen-Positive Lesions. Clinical Nuclear Medicine, 45(2), 105-112. https://dx.doi.org/10.1097/RLU.0000000000002880
• Schmidkonz, C., Götz, T.I., Atzinger, A., Ritt, P., Prante, O., Kuwert, T.,... Cordes, M. (2020). 99mTc-MIP-1404 SPECT/CT for Assessment of Whole-Body Tumor Burden and Treatment Response in Patients With Biochemical Recurrence of Prostate Cancer. Clinical Nuclear Medicine. https://dx.doi.org/10.1097/RLU.0000000000003102
• Schmidkonz, C., Krumbholz, M., Atzinger, A., Cordes, M., Götz, T., Prante, O.,... Metzler, M. (2020). Correction to: Assessment of treatment responses in children and adolescents with Ewing sarcoma with metabolic tumor parameters derived from 18F-FDG-PET/CT and circulating tumor DNA (European Journal of Nuclear Medicine and Molecular Imaging, (2019), 10.1007/s00259-019-04649-1). European Journal of Nuclear Medicine and Molecular Imaging. https://dx.doi.org/10.1007/s00259-019-04672-2
• Schmidkonz, C., Rauber, S., Atzinger, A., Agarwal, R., Götz, T.I., Soare, A.,... Ramming, A. (2020). Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging. Annals of the Rheumatic Diseases, 79(11), 1485-1491. https://dx.doi.org/10.1136/annrheumdis-2020-217408
• Shi, C., Kim, T., Steiger, S., Mulay, S.R., Klinkhammer, B.M., Bäuerle, T.,... Anders, H.J. (2020). Crystal clots as therapeutic target in cholesterol crystal embolism. Circulation Research, E37-E52. https://dx.doi.org/10.1161/CIRCRESAHA.119.315625
• Soare, A., Györfi, A.-H., Matei, A.-E., Dees, C., Rauber, S., Wohlfahrt, T.,... Ramming, A. (2020). Dipeptidylpeptidase 4 as a Marker of Activated Fibroblasts and a Potential Target for the Treatment of Fibrosis in Systemic Sclerosis. Arthritis and Rheumatology, 72(1), 137-149. https://dx.doi.org/10.1002/art.41058
• Treutlein, C., Bäuerle, T., Nagel, A.M., Guermazi, A., Kleyer, A., Simon, D.,... Roemer, F. (2020). Comprehensive assessment of knee joint synovitis at 7 T MRI using contrast-enhanced and non-enhanced sequences. BMC Musculoskeletal Disorders, 21(1). https://dx.doi.org/10.1186/s12891-020-3122-y
• Treutlein, C., Stollberg, A., Scherl, C., Agaimy, A., Ellmann, S., Iro, H.,... Bäuerle, T. (2020). Diagnostic value of 3D dynamic contrast-enhanced magnetic resonance imaging in lymph node metastases of head and neck tumors: a correlation study with histology. Acta Radiologica Open, 9(8). https://dx.doi.org/10.1177/2058460120951966
• Xu, M.M., Seyler, L., Bäuerle, T., Kalinichenko, L., Müller, C.P., Huttner, H.,... Manaenko, A. (2020). Serelaxin activates eNOS, suppresses inflammation, attenuates developmental delay and improves cognitive functions of neonatal rats after germinal matrix hemorrhage. Scientific Reports, 10(1). https://dx.doi.org/10.1038/s41598-020-65144-4