Prof. Dr. Christoph Bert

Research projects

Medical physics in radiation therapy with a focus on quality assurance for brachytherapy
Management of organ motion (4DCT, tracking)
Optimization of imaging for RT treatment planning.
Electromagnetic tracking for quality assurance in interstitial brachytherapy
Digital Twin for online validation of Medical device networks –
Optimization of MR imaging for radiotherapy
Risk management in radiation therapy –
Several topics w.r.t. Optimizing the therapy
Quality assurance

Bildgestützte Brachytherapie mit navigierter Echtzeit-Nadelführung

(Third Party Funds Single)

Project leader: Christoph Bert, Andre Karius
Term: 1. November 2025 - 31. October 2028
Acronym: ST-DFG_SBH_BE 4266/5-1
Funding source: DFG-Einzelförderung / Sachbeihilfe (EIN-SBH)

Abstract

Interventional radiation therapy (brachytherapy) suffers from the lack of dedicated and flexible protocols for the quantitative assessment of needle insertion accuracy throughout the intervention. Despite the recent advances in the use of cone-beam CT (CBCT) imaging for guidance, the effective implementation of image-guided procedures is limited by procedural constraints. Also, the optimal trade-off between accurate 3D imaging on one hand and fast verification of the needle position during the procedure on the other is largely unexplored. The proposed project focuses therefore on specific developments towards the implementation of image-guided protocols in brachytherapy featuring real-time navigated needle insertion. We aim at exploiting the integration of infrared navigation technologies with mobile CBCT imaging to develop image-guided protocols, with the twofold aim to provide quantitative verification methods and improve image quality. This is intended to address brachytherapy treatments at different treatment sites, including those where image quality is degraded by the effects of intra-fractional motion. We also aim at leveraging Artificial intelligence (AI) methods to enable accurate and reliable needle tracking in X-ray imaging, thus maximizing the confidence level in the execution of accurate brachytherapy treatments. The overall scientific goal of the proposed project will be achieved through the following specific objectives, as a collaborative research effort across three different research institutions sharing the same technological platform: (i) to exploit integrated infrared tracking technologies for navigated needle insertion; (ii) to provide automated tracking of the needle position in X-ray verification images based on AI methods; (iii) to optimize imaging verification protocols relying on the best combination of 3D/sparse 2D imaging; (iv) to enhance CBCT image quality, especially for treatment sites undergoing significant breathing motion. The achievement of such objectives is expected to lead to the implementation of reliable image verification protocols in brachytherapy, complementing real-time guided needle insertion to maximize the accuracy.

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Verbundprojekt: Intelligente Tumorverfolgung für die Strahlentherapie (INSIGHT) - Teilvorhaben: Echtzeitverfolgung von Tumorzielvolumina Autosegmentierung und Validierung

(Third Party Funds Group – Sub project)

Overall project: Intelligente Tumorverfolgung für die Strahlentherapie (INSIGHT)
Project leader: Christoph Bert, Florian Putz
Term: 1. June 2024 - 31. May 2027
Acronym: ST-BMBF_INSIGHT
Funding source: BMBF / Verbundprojekt

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Entwicklung eines Datenanalyse- und Kommunikations-Clusters zur Unterstützung klinischer Abläufe mit dem Ziel der Steigerung der Behandlungsqualität

(Third Party Funds Single)

Project leader: Christoph Bert
Term: 1. April 2024 - 31. March 2027
Acronym: DAKomMed
Funding source: Bayerisches Staatsministerium für Wirtschaft, Landesentwicklung und Energie (StMWi) (seit 2018)

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2022

Dörfler, A., Huang, Y., Bert, C., Sommer, P., Frey, B., Gaipl, U.,... Putz, F. (2022). Improvement of Deep Learning-based Auto-detection of Brain Metastases by Integrating previous MRI Images. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S6-S6). HEIDELBERG: SPRINGER HEIDELBERG.
Dürrbeck, C., Abu-Hossin, N., Lotter, M., Kreppner, S., Lubgan, D., Fietkau, R.,... Bert, C. (2022). Automatisation of catheter reconstruction in interstitial breast BT using electromagnetic tracking. In RADIOTHERAPY AND ONCOLOGY (pp. S561-S562). CLARE: ELSEVIER IRELAND LTD.
Dürrbeck, C., Fietkau, R., Strnad, V., & Bert, C. (2022). Automation of Implant Reconstruction in Interstitial Brachytherapy of the Breast Using Electromagnetic Tracking. In MEDICAL PHYSICS (pp. E171-E171). HOBOKEN: WILEY.
Dürrbeck, C., Gulde, S., Abu-Hossin, N., Fietkau, R., Strnad, V., & Bert, C. (2022). Influence and compensation of patient motion in electromagnetic tracking based quality assurance in interstitial brachytherapy of the breast. Medical Physics. https://doi.org/10.1002/mp.15517
Dürrbeck, C., Sauer, B., Lotter, M., Kreppner, S., Strnad, V., Fietkau, R., & Bert, C. (2022). Automating implant reconstruction in interstitial brachytherapy of the breast: A hybrid approach combining electromagnetic tracking and image segmentation. Radiotherapy and Oncology, 176, 172-178. https://doi.org/10.1016/j.radonc.2022.09.019
Freislederer, P., Batista, V., Ollers, M., Buschmann, M., Steiner, E., Kugele, M.,... Lehmann, J. (2022). ESTRO-ACROP guideline on surface guided radiation therapy. Radiotherapy and Oncology, 173, 188-196. https://doi.org/10.1016/j.radonc.2022.05.026
Garibaldi, C., Essers, M., Heijmen, B., Bertholet, J., Koutsouveli, E., Schwarz, M.,... Clark, C.H. (2022). The 3rd ESTRO-EFOMP core curriculum for medical physics experts in radiotherapy. Radiotherapy and Oncology. https://doi.org/10.1016/j.radonc.2022.02.012
Grigo, J., Karius, A., Hanspach, J., Weissmann, T., Laun, F.B., Strnad, V.,... Bert, C. (2022). Possibilities of a Seed Control after the Implantation by using MRI and Deep Learning-based QSM Reconstruction. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S54-S55). HEIDELBERG: SPRINGER HEIDELBERG.
Huang, Y., Bert, C., Sommer, P., Frey, B., Gaipl, U., Distel, L.,... Putz, F. (2022). Deep learning for brain metastasis detection and segmentation in longitudinal MRI data. Medical Physics. https://doi.org/10.1002/mp.15863
Huang, Y., Bert, C., Sommer, P., Frey, B., Gaipl, U., Distel, L.,... Putz, F. (2022). Verbesserung der Deep Learning basierten Autodetektion von Hirnmetastasen durch Integration von MRT-Voraufnahmen. In Strahlentherapie und Onkologie (S. S6). Stuttgart, DE: Springer.
Huang, Y., Maier, A., Sommer, P., Fischer, S., Srinivasan, A.L., Fietkau, R.,... Putz, F. (2022). Deep Learning based Prediction of Glioma Growth by using "Growing Neural Cellular Automata". In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S65-S65). HEIDELBERG: SPRINGER HEIDELBERG.
Huang, Y., Maier, A., Sommer, P., Fischer, S., Srinivasan, A.L., Fietkau, R.,... Putz, F. (2022). Deep Learning basierte Vorhersage von Gliomwachstum mittels Growing Neural Cellular Automata. In Strahlentherapie und Onkologie (S. S65). Stuttgart, DE: Springer.
Kahlert, B., Bert, C., Rückert, M., Hensel, B., Root, K., Vossiek, M.,... Frey, B. (2022). Creation of an Electro-magnetic Heat Simulation for Planning Hyperthermia Treatments for Mice. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S173-S174). HEIDELBERG: SPRINGER HEIDELBERG.
Karius, A., & Bert, C. (2022). QAMaster: A new software framework for phantom-based computed tomography quality assurance. Journal of Applied Clinical Medical Physics. https://doi.org/10.1002/acm2.13588
Karius, A., Lotter, M., Kreppner, S., Lubgan, D., Grigo, J., Fietkau, R.,... Bert, C. (2022). Low-dose-rate Prostate Brachytherapy: Characterization of Seeds Dynamics within the Prostate. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S118-S119). HEIDELBERG: SPRINGER HEIDELBERG.
Karius, A., Lotter, M., Kreppner, S., Schaller, V., Lubgan, D., Grigo, J.,... Bert, C. (2022). Permanent LDR prostate brachytherapy: Comprehensive characterization of seed-dynamics within the prostate on a seed-only level. Brachytherapy, 21(5), 635-646. https://doi.org/10.1016/j.brachy.2022.04.007
Karius, A., Strnad, V., Lotter, M., Kreppner, S., & Bert, C. (2022). First clinical experience with a novel, mobile cone-beam CT system for treatment quality assurance in brachytherapy. Strahlentherapie und Onkologie. https://doi.org/10.1007/s00066-022-01912-7
Karius, A., Szkitsak, J., Boronikolas, V., Fietkau, R., & Bert, C. (2022). Quality assurance and long-term stability of a novel 3-in-1 X-ray system for brachytherapy. Journal of Applied Clinical Medical Physics. https://doi.org/10.1002/acm2.13727
Khatun, R., Hader, M., Schmidt, M., Bert, C., Wadepohl, M., Fietkau, R.,... Frey, B. (2022). Magnetic Resonance thermometry images of hyperthermia treatments of sarcomas for prediction of therapy responses-need of data reprocessing and cleaning. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S69-S69). HEIDELBERG: SPRINGER HEIDELBERG.
Kornek, D., Lang-Welzenbach, M., Beck, A., Reinhardt, A., Brandt, T., & Bert, C. (2022). Reporting and Evaluation System for Incidents in the Radiation Therapy to increase Patient Safety, Treatment Quality and the Efficiency of Process Flows. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S174-S175). HEIDELBERG: SPRINGER HEIDELBERG.
Li, H., Dong, L., Bert, C., Chang, J., Flampouri, S., Jee, K.-W.,... Vedam, S. (2022). AAPM Task Group Report 290: Respiratory motion management for particle therapy. Medical Physics. https://doi.org/10.1002/mp.15470
Lohmann, D., Lang-Welzenbach, M., Feldberger, L., Sommer, E., Bücken, S., Lotter, M.,... Bert, C. (2022). Risk analysis for radiotherapy at the Universitätsklinikum Erlangen. Zeitschrift für Medizinische Physik. https://doi.org/10.1016/j.zemedi.2021.11.002
Lohmann, D., Shariff, M., Schubert, P., Sauer, T.-O., Fietkau, R., & Bert, C. (2022). Unified risk analysis in radiation therapy. Zeitschrift für Medizinische Physik. https://doi.org/10.1016/j.zemedi.2022.08.006
Maksoud, Z., Schmidt, M., Huang, Y., Rutzner, S., Mansoorian, S., Weissmann, T.,... Putz, F. (2022). Transient Enlargement in Meningiomas Treated with Stereotactic Radiotherapy. Cancers, 14(Special Issue State-of-the-Art Research in Meningioma), 1-13. https://doi.org/10.3390/cancers14061547
Masitho, S., Grigo, J., Szkitsak, J., Reissig, L., Fietkau, R., Putz, F., & Bert, C. (2022). Feasibility of daily kV-Recording-based Positioning by using DRRs from an AI-based synthetic CT for MR-only intracranial Stereotactic Radiotherapy. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S18-S19). HEIDELBERG: SPRINGER HEIDELBERG.
Masitho, S., Putz, F., Mengling, V., Reißig, L., Voigt, R., Bäuerle, T.,... Bert, C. (2022). Accuracy of MRI-CT registration in brain stereotactic radiotherapy: Impact of MRI acquisition setup and registration method. Zeitschrift für Medizinische Physik. https://doi.org/10.1016/j.zemedi.2022.04.004
Masitho, S., Szkitsak, J., Grigo, J., Fietkau, R., Putz, F., & Bert, C. (2022). Feasibility of artificial-intelligence-based synthetic computed tomography in a magnetic resonance-only radiotherapy workflow for brain radiotherapy: Two-way dose validation and 2D/2D kV-image-based positioning. Physics and Imaging in Radiation Oncology, 24, 111-117. https://doi.org/10.1016/j.phro.2022.10.002
Masitho, S., Szkitsak, J., Grigo, J., Putz, F., Fietkau, R., & Bert, C. (2022). Two-ways validation of the feasibility of AI-based synthetic CT for MR-only brain radiotherapy. In RADIOTHERAPY AND ONCOLOGY (pp. S283-S283). CLARE: ELSEVIER IRELAND LTD.
Putz, F., Chen, H.-F., Huang, Y., Weissmann, T., Mansoorian, S., Schmidt, M.,... Fietkau, R. (2022). Deep Learning-based automatic longitudinal volumetric Analysis in Acoustic Neuroma. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S67-S67). HEIDELBERG: SPRINGER HEIDELBERG.
Putz, F., Görnert, C., Voigt, R., Grigo, J., Masitho, S., Reissig, L.,... Fietkau, R. (2022). Quantification of pretherapeutic Changes in Brain Metastases before stereotactic Radiotherapy. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S130-S130). HEIDELBERG: SPRINGER HEIDELBERG.
Putz, F., Huang, Y., Weissmann, T., Mansoorian, S., Lamrani, A., Sommer, P.,... Bert, C. (2022). Assessing Organ-at-risk Auto-contouring Solutions: Which Metrics are most predictive of clinical Time Savings? In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S67-S68). HEIDELBERG: SPRINGER HEIDELBERG.
Putz, F., Huang, Y., Weissmann, T., Mansoorian, S., Sommer, P., Fischer, S.,... Fietkau, R. (2022). Deep Learning based fully automated volumetric Progression Assessment in Patients with Brain Metastases after stereotactic Radiotherapy. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S49-S49). HEIDELBERG: SPRINGER HEIDELBERG.
Putz, F., Siavooshhaghighi, H., Grigo, J., Masitho, S., Huang, Y., Weissmann, T.,... Fietkau, R. (2022). Influence of MRI Distortion Correction on the local Control of stereotactically irradiated Brain Metastases. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S29-S29). HEIDELBERG: SPRINGER HEIDELBERG.
Sauer, B., Dürrbeck, C., & Bert, C. (2022). Electromagnetic tracking in interstitial brachytherapy: A systematic review. Frontiers in Physics, 10. https://doi.org/10.3389/fphy.2022.956983
Sauer, T.-O., Ott, O., & Bert, C. (2022). Dosimetric evaluation of 6-DOF intra-fraction motion for SGRT of breast cancer patients. In RADIOTHERAPY AND ONCOLOGY (pp. S1521-S1522). CLARE: ELSEVIER IRELAND LTD.
Sauer, T.-O., Ott, O., Lahmer, G., Fietkau, R., & Bert, C. (2022). Prerequisites for the clinical implementation of a markerless SGRT-only workflow for the treatment of breast cancer patients. Strahlentherapie und Onkologie. https://doi.org/10.1007/s00066-022-01966-7
Shariff, M., Lotter, M., Lambrecht, U., & Bert, C. (2022). Integration of a Halcyon Accelerator with ARIA in a Mosaiq - Environment - Risk Analysis Procedure. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S169-S170). HEIDELBERG: SPRINGER HEIDELBERG.
Shariff, M., Stillkrieg, W., Lotter, M., Lohmann, D., Weissmann, T., Fietkau, R., & Bert, C. (2022). Dosimetry, Optimization and FMEA of Total Skin Electron Irradiation (TSEI). Zeitschrift für Medizinische Physik, 32(2), 228-239. https://doi.org/10.1016/j.zemedi.2021.09.004
Sommer, P., Huang, Y., Fischer, S., Srinivasan, A.L., Dörfler, A., Schmidt, M.,... Putz, F. (2022). Identification of High-risk Metastases in MRI Follow-up after Stereotaxic by using Radiomics and Delta Radiomics. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S64-S64). HEIDELBERG: SPRINGER HEIDELBERG.
Sommer, P., Huang, Y., Srinivasan, A.L., Fischer, S., Dörfler, A., Schmidt, M.,... Putz, F. (2022). Distinguishing Progression and Radionecrosis in large progressive Brain Metastases after Stereotaxy by integrating Radiomics, Dose Radiomics and clinical Risk Factors. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S19-S20). HEIDELBERG: SPRINGER HEIDELBERG.
Szkitsak, J., Karius, A., Hofmann, C., Fietkau, R., Bert, C., & Speer, S. (2022). Quality assurance of a breathing controlled four-dimensional computed tomography algorithm. Physics and Imaging in Radiation Oncology, 23, 85-91. https://doi.org/10.1016/j.phro.2022.06.007
Voigt, R., Masitho, S., Grigo, J., Reissig, L., Uder, M., Semrau, S.,... Putz, F. (2022). Change in the radio-oncological Treatment Concept for Brain Metastases through a dedicated Radiotherapy Planning MRI. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S54-S54). HEIDELBERG: SPRINGER HEIDELBERG.
Weissmann, T., Huang, Y., Sommer, P., Roesch, J., Mansoorian, S., Ayala, H.,... Putz, F. (2022). Deep Learning-based Auto-contouring of Lymph Node Levels in Head and Neck Area. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S20-S21). HEIDELBERG: SPRINGER HEIDELBERG.
Weissmann, T., Huang, Y., Speer, S., Semrau, S., Bert, C., Fietkau, R., & Putz, F. (2022). Analysis of Head and Neck Lymph Node Metastasis Distribution by using Deep Learning automated Lymph Node Level Contouring. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S53-S53). HEIDELBERG: SPRINGER HEIDELBERG.

2021

Abu-Hossin, N., Gulde, S., Dürrbeck, C., Strnad, V., Fietkau, R., & Bert, C. (2021). Quality assurance of curved catheter paths in interstitial brachytherapy using a constructed phantom. In RADIOTHERAPY AND ONCOLOGY (pp. S110-S111). CLARE: ELSEVIER IRELAND LTD.
Abu-Hossin, N., Kallis, K., Strnad, V., Fietkau, R., & Bert, C. (2021). Impact of patient positioning on interstitial multicatheter HDR brachytherapy of the breast. In RADIOTHERAPY AND ONCOLOGY (pp. S76-S76). CLARE: ELSEVIER IRELAND LTD.
Caruana, C.J., Karenauskaite, V., Mornstein, V., Vano, E., Pace, E., Lammertsma, A.A.,... Winiecki, J. (2021). A generic curriculum development model for the biomedical physics component of the educational and training programmes of the non-physics healthcare professions. Physica Medica, 85, 32-41. https://doi.org/10.1016/j.ejmp.2021.04.015
Dürrbeck, C., Pflaum, L., Schulz, M., Kallis, K., Geimer, T., Abu-Hossin, N.,... Bert, C. (2021). Implant-based CT estimation towards adaptive breast brachytherapy. In RADIOTHERAPY AND ONCOLOGY (pp. S76-S77). CLARE: ELSEVIER IRELAND LTD.
Filimonova, I., Schmidt, D., Mansoorian, S., Weissmann, T., Siavooshhaghighi, H., Kuwert, T.,... Cavallaro, A.J. (2021). The Distribution of Pelvic Nodal Metastases in Prostate Cancer Reveals Potential to Advance and Personalize Pelvic Radiotherapy. Frontiers in Oncology, 10. https://doi.org/10.3389/fonc.2020.590722
Garibaldi, C., Essers, M., Heijmen, B., Bertholet, J., Koutsouveli, E., Schwarz, M.,... Clark, C.H. (2021). Update of the ESTRO-EFOMP core curriculum for medical physics experts in radiotherapy. In RADIOTHERAPY AND ONCOLOGY (pp. S207-S209). CLARE: ELSEVIER IRELAND LTD.
Grigo, J., Masitho, S., Putz, F., Fietkau, R., & Bert, C. (2021). Evaluation of a dedicated Treatment Planning-MRI for Patients with cranial Stereotaxy. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S221-S221). HEIDELBERG: SPRINGER HEIDELBERG.
Karius, A., Karolczak, M., Strnad, V., & Bert, C. (2021). Technical evaluation of the cone-beam computed tomography imaging performance of a novel, mobile, gantry-based X-ray system for brachytherapy. Journal of Applied Clinical Medical Physics. https://doi.org/10.1002/acm2.13501
Karius, A., Strnad, V., & Bert, C. (2021). New, mobile CBCT-System (ImagingRing m) for image-guided Brachytherapy - Quality Assurance. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S38-S39). HEIDELBERG: SPRINGER HEIDELBERG.
Maas, A.J., Lammertsma, A.A., Agius, S., Bert, C., Byrne, B., Caruana, C.J.,... Brambilla, M. (2021). Education, training and registration of Medical Physics Experts across Europe. Physica Medica, 85, 129-136. https://doi.org/10.1016/j.ejmp.2021.03.034
Mansoorian, S., Coras, R., Weissmann, T., Lettmaier, S., Semrau, S., Frey, B.,... Putz, F. (2021). Reirradiation of recurent glioblastomas: High prognostic significance of contrast-enhancing tumor volume. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S87-S87). HEIDELBERG: SPRINGER HEIDELBERG.
Oft, D., Schmidt, M., Weissmann, T., Roesch, J., Mengling, V., Masitho, S.,... Putz, F. (2021). Volumetric Regression in Brain Metastases After Stereotactic Radiotherapy: Time Course, Predictors, and Significance. Frontiers in Oncology, 10. https://doi.org/10.3389/fonc.2020.590980
Putz, F., Lamrani, A., Weissmann, T., Mansoorian, S., Frey, B., Bert, C., & Fietkau, R. (2021). The OAR Turing-Test Study: A blinded Comparison of expert-Based Organ at Risk Creation and three commercial Auto-Segmentation Solutions. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S6-S6). HEIDELBERG: SPRINGER HEIDELBERG.
Putz, F., Weissmann, T., Mansoorian, S., Schmidt, M., Heiß, R., Semrau, S.,... Fietkau, R. (2021). 3D convolutional neural network-based autosegmentation improves brain metastases detection and quantification for brain stereotactic radiotherapy treatment planning. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S85-S86). HEIDELBERG: SPRINGER HEIDELBERG.
Putz, F., Weissmann, T., Mansoorian, S., Schmitter, C., Semrau, S., Lettmaier, S.,... Fietkau, R. (2021). High Detection Accuracy of an optimized 3D Convolutional Neural Network for Auto Detection and Auto Segmentation of Brain Metastases. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S50-S51). HEIDELBERG: SPRINGER HEIDELBERG.
Sauer, T.-O., Ott, O., Lahmer, G., Fietkau, R., & Bert, C. (2021). Region of interest optimization for radiation therapy of breast cancer. Journal of Applied Clinical Medical Physics. https://doi.org/10.1002/acm2.13410
Sauer, T.-O., Popp, D., Ott, O.J., & Bert, C. (2021). Evaluation of a markerless SGRT-only workflow for breast cancer patients. In RADIOTHERAPY AND ONCOLOGY (pp. S1432-S1432). CLARE: ELSEVIER IRELAND LTD.
Schmitter, C., Weissmann, T., Mansoorian, S., Lettmaier, S., Semrau, S., Schmidt, M.,... Putz, F. (2021). Longitudinal Spread Analysis of Patients with Glioblastoma: high Prevalence of discontinuous Tumor Foci with no strong Relation to the Fibrous Tract System. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S45-S46). HEIDELBERG: SPRINGER HEIDELBERG.
Shariff, M., Lotter, M., Stillkrieg, W., & Bert, C. (2021). Implementation of Whole Skin Therapy: Dosimetry, Optimization and FMEA Analysis. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S228-S228). HEIDELBERG: SPRINGER HEIDELBERG.
Szkitsak, J., Werner, R., Fernolendt, S., Schwarz, A., Ott, O., Fietkau, R.,... Bert, C. (2021). First clinical evaluation of breathing controlled four-dimensional computed tomography imaging. Physics and Imaging in Radiation Oncology, 20, 56-61. https://doi.org/10.1016/j.phro.2021.09.005
Weissmann, T., Höfler, D., Hecht, M., Semrau, S., Haderlein, M., Filimonova, I.,... Putz, F. (2021). Oligometastatic head and neck cancer: Which patients benefit from radical local treatment of all tumour sites? Radiation Oncology, 16(1). https://doi.org/10.1186/s13014-021-01790-w
Weissmann, T., Lettmaier, S., Donaubauer, A.-J., Bert, C., Schmidt, M., Kruse, F.,... Putz, F. (2021). Low- vs. high-dose radiotherapy in Graves’ ophthalmopathy: a retrospective comparison of long-term results. Strahlentherapie und Onkologie. https://doi.org/10.1007/s00066-021-01770-9
Weissmann, T., Speer, S., Putz, F., Lettmaier, S., Schubert, P., Shariff, M.,... Hecht, M. (2021). Reduction of elective radiotherapy treatment volume in definitive treatment of locally advanced head and neck cancer—comparison of a prospective trial with a revised simulated contouring approach. Journal of Clinical Medicine, 10(20). https://doi.org/10.3390/jcm10204653
Werner, R., Szkitsak, J., Sentker, T., Madesta, F., Schwarz, A., Fernolendt, S.,... Hofmann, C. (2021). Comparison of intelligent 4D CT sequence scanning and conventional spiral 4D CT: A first comprehensive phantom study. Physics in Medicine and Biology, 66(1). https://doi.org/10.1088/1361-6560/abc93a
Witulla, B., Ziegler, M., Brandt, T., Prasetio, H., Fietkau, R., & Bert, C. (2021). Quality assurance for dynamic tumor tracking. Zeitschrift für Medizinische Physik. https://doi.org/10.1016/j.zemedi.2021.01.002

2020

Baltas, D., Ladd, M.E., Fiebich, M., Bert, C., & Heufelder, J. (2020). Hemicorporal paresthesias in a parvovirusinfection. Zeitschrift für Medizinische Physik, 30(4), 328-341. https://doi.org/10.1016/j.zemedi.2020.10.001
Bayer, S., Spiske, U., Geimer, T., Luo, J., Wells III, W.M., Ostermeier, M.,... Maier, A. (2020). An Investigation of Feature-based Nonrigid Image Registration using Gaussian Process. In Springer (Eds.), Algorithmen – Systeme – Anwendungen. Proceedings des Workshops. Berlin: Springer.
Bert, C. (2020). Clinical experience with markerless tumor tracking. In RADIOTHERAPY AND ONCOLOGY (pp. S424-S424). CLARE: ELSEVIER IRELAND LTD.
Böckelmann, F., Putz, F., Kallis, K., Lettmaier, S., Fietkau, R., & Bert, C. (2020). Adaptive radiotherapy and the dosimetric impact of inter- and intrafractional motion on the planning target volume for prostate cancer patients. Strahlentherapie und Onkologie. https://doi.org/10.1007/s00066-020-01596-x
Filimonova, I., Weissmann, T., Mansoorian, S., Bert, C., Frey, B., Fietkau, R., & Putz, F. (2020). Patterns of lymph node involvement in prostate cancer patients presenting for pelvic and paraaortic stereotactic radiotherapy of nodal metastases. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S157-S158). Weisbaden, DE: HEIDELBERG: SPRINGER HEIDELBERG.
Freislederer, P., Kügele, M., Öllers, M., Swinnen, A., Sauer, T.-O., Bert, C.,... Batista, V. (2020). Correction to: Recent advances in Surface Guided Radiation Therapy (Radiation Oncology, (2020), 15, 1, (187), 10.1186/s13014-020-01629-w). Radiation Oncology, 15(1). https://doi.org/10.1186/s13014-020-01661-w
Freislederer, P., Kügele, M., Öllers, M., Swinnen, A., Sauer, T.-O., Bert, C.,... Batista, V. (2020). Recent advanced in Surface Guided Radiation Therapy. Radiation Oncology, 15(1), 187-. https://doi.org/10.1186/s13014-020-01629-w
Mansoorian, S., Mengling, V., Masitho, S., Perrin, R., Siavooshaghighi, H., Weissmann, T.,... Putz, F. (2020). T1-SPACE vs. T1-MPRAGE for Target Volume Definition in Brain Metastases - a radiotherapy-oriented Comparison. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S127-S128). Weisbaden, DE: HEIDELBERG: SPRINGER HEIDELBERG.
Mengling, V., Bert, C., Perrin, R., Masitho, S., Weissmann, T., Mansoorian, S.,... Putz, F. (2020). Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position. Strahlentherapie und Onkologie. https://doi.org/10.1007/s00066-020-01703-y
Mengling, V., Perrin, R., Putz, F., Fietkau, R., & Bert, C. (2020). Comparison of MRI coils and RT-positioning systems for optimal MRI scanning in SRS cases. In RADIOTHERAPY AND ONCOLOGY (pp. S972-S972). CLARE: ELSEVIER IRELAND LTD.
Mengling, V., Putz, F., Laun, F.B., Perrin, R., Eisenhut, F., Dörfler, A.,... Bert, C. (2020). Evaluation of the influence of susceptibility-induced magnetic field distortions on the precision of contouring intracranial organs at risk for stereotactic radiosurgery. Physics and Imaging in Radiation Oncology, 15, 91-97. https://doi.org/10.1016/j.phro.2020.08.001
Mengling, V., Putz, F., Perrin, R., Fietkau, R., & Bert, C. (2020). Does a dedicated Radiation Planning MRI add Value to cranial Stereotaxy? In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S67-S67). Weisbaden, DE: HEIDELBERG: SPRINGER HEIDELBERG.
Putz, F., Mengling, V., Masitho, S., Perrin, R., Roesch, J., Weissmann, T.,... Bert, C. (2020). Does the Planning MRI for cranial Stereotaxy have to be performed in the Irradiation Position? An Examination of Brain Tissue Deformations between MR Imaging in diagnostic and Radiation Positions. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S200-S201). Weisbaden, DE: HEIDELBERG: SPRINGER HEIDELBERG.
Putz, F., Mengling, V., Perrin, R., Masitho, S., Weissmann, T., Roesch, J.,... Cavallaro, A.J. (2020). Magnetic resonance imaging for brain stereotactic radiotherapy - A review of requirements and pitfalls. Strahlentherapie und Onkologie. https://doi.org/10.1007/s00066-020-01604-0
Putz, F., Oft, D., Perrin, R., Mengling, V., Weissmann, T., Roesch, J.,... Fietkau, R. (2020). Volumetric regression in brain metastases after stereotactic RT: Time course and significance. In RADIOTHERAPY AND ONCOLOGY (pp. S82-S83). CLARE: ELSEVIER IRELAND LTD.
Putz, F., Weissmann, T., Oft, D., Schmidt, M., Roesch, J., Siavooshhaghighi, H.,... Fietkau, R. (2020). FSRT vs. SRS in Brain Metastases—Differences in Local Control and Radiation Necrosis—A Volumetric Study. Frontiers in Oncology, 10. https://doi.org/10.3389/fonc.2020.559193
Sauer, T.-O., Popp, D., Fietkau, R., & Bert, C. (2020). ROI optimisation for surface guided radiation therapy. In RADIOTHERAPY AND ONCOLOGY (pp. S1062-S1062). CLARE: ELSEVIER IRELAND LTD.
Serpa, M., & Bert, C. (2020). Dense feature-based motion estimation in MV fluoroscopy during dynamic tumor tracking treatment: preliminary study on reduced aperture and partial occlusion handling. Physics in Medicine and Biology, 65(24). https://doi.org/10.1088/1361-6560/abc6f3
Siavooshhaghighi, H., Mengling, V., Masitho, S., Filimonova, I., Mansoorian, S., Weissmann, T.,... Putz, F. (2020). Evaluation of a high-resolution 3D T2-SPACE-FLAIR Sequence in Comparison to the conventional 2D T2-FLAIR Sequence for the Contouring of low malignant Tumor Parts in cerebral Gliomas. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S69-S69). Weisbaden, DE: HEIDELBERG: SPRINGER HEIDELBERG.
Witulla, B., Goerig, N., Putz, F., Frey, B., Engelhorn, T., Dörfler, A.,... Laun, F.B. (2020). On PTV definition for glioblastoma based on fiber tracking of diffusion tensor imaging data. PLoS ONE, 15(1), e0227146-. https://doi.org/10.1371/journal.pone.0227146

Prof. Dr. Christoph Bert

Research projects

Bildgestützte Brachytherapie mit navigierter Echtzeit-Nadelführung

Verbundprojekt: Intelligente Tumorverfolgung für die Strahlentherapie (INSIGHT) - Teilvorhaben: Echtzeitverfolgung von Tumorzielvolumina Autosegmentierung und Validierung

Entwicklung eines Datenanalyse- und Kommunikations-Clusters zur Unterstützung klinischer Abläufe mit dem Ziel der Steigerung der Behandlungsqualität

2025

2024

2023

2022

2021

2020

Related Research Fields

Contact:

Research projects

Current projects

Bildgestützte Brachytherapie mit navigierter Echtzeit-Nadelführung

Verbundprojekt: Intelligente Tumorverfolgung für die Strahlentherapie (INSIGHT) - Teilvorhaben: Echtzeitverfolgung von Tumorzielvolumina  Autosegmentierung und Validierung

Entwicklung eines Datenanalyse- und Kommunikations-Clusters zur Unterstützung klinischer Abläufe mit dem Ziel der Steigerung der Behandlungsqualität

Recent publications

2025

2024

2023

2022

2021

2020

Related Research Fields

Contact:

Verbundprojekt: Intelligente Tumorverfolgung für die Strahlentherapie (INSIGHT) - Teilvorhaben: Echtzeitverfolgung von Tumorzielvolumina Autosegmentierung und Validierung