Prof. Dr. Frederik Laun

2023

• Cognolato, F., O'Brien, K., Jin, J., Robinson, S., Laun, F.B., Barth, M., & Bollmann, S. (2023). NeXtQSM—A complete deep learning pipeline for data-consistent Quantitative Susceptibility Mapping trained with hybrid data. Medical Image Analysis, 84. https://dx.doi.org/10.1016/j.media.2022.102700

2022

• Führes, T., Saake, M., Lorenz, J., Seuß, H., Stemmer, A., Benkert, T.,... Laun, F.B. (2022). Reduction of the cardiac pulsation artifact and improvement of lesion conspicuity in flow-compensated diffusion images in the liver-A quantitative evaluation of postprocessing algorithms. Magnetic Resonance in Medicine. https://dx.doi.org/10.1002/mrm.29427
• Glang, F., Fabian, M.S., German, A., Khakzar, K., Mennecke, A., Liebert, A.,... Laun, F.B. (2022). Linear projection-based CEST parameter estimation. NMR in Biomedicine. https://dx.doi.org/10.1002/nbm.4697
• Grigo, J., Karius, A., Hanspach, J., Weissmann, T., Laun, F.B., Strnad, V.,... Bert, C. (2022). Possibilities of a Seed Control after the Implantation by using MRI and Deep Learning-based QSM Reconstruction. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S54-S55). HEIDELBERG: SPRINGER HEIDELBERG.
• Hammon, M., Saake, M., Laun, F.B., Heiß, R., Seuss, N., Janka, R.M.,... Seuß, H. (2022). Improved Visualization of Prostate Cancer Using Multichannel Computed Diffusion Images: Combining ADC and DWI. Diagnostics, 12(7). https://dx.doi.org/10.3390/diagnostics12071592
• Hanspach, J., Bollmann, S., Grigo, J., Karius, A., Uder, M., & Laun, F.B. (2022). Deep learning–based quantitative susceptibility mapping (QSM) in the presence of fat using synthetically generated multi-echo phase training data. Magnetic Resonance in Medicine. https://dx.doi.org/10.1002/mrm.29265
• Kapsner, L., Ohlmeyer, S., Folle, L., Laun, F.B., Nagel, A.M., Liebert, A.,... Bickelhaupt, S. (2022). Automated artifact detection in abbreviated dynamic contrast-enhanced (DCE) MRI-derived maximum intensity projections (MIPs) of the breast. European Radiology. https://dx.doi.org/10.1007/s00330-022-08626-5
• Laun, F.B., Führes, T., Seuß, H., Müller, A., Bickelhaupt, S., Stemmer, A.,... Saake, M. (2022). Flow-compensated diffusion encoding in MRI for improved liver metastasis detection. PLoS ONE, 17(5 5). https://dx.doi.org/10.1371/journal.pone.0268843
• Ludwig, D., Laun, F.B., Klika, K.D., Rauch, J., Ladd, M.E., Bachert, P., & Kuder, T.A. (2022). Diffusion pore imaging in the presence of extraporal water. Journal of Magnetic Resonance, 339. https://dx.doi.org/10.1016/j.jmr.2022.107219
• Mennecke, A., Khakzar, K.M., German, A., Herz, K., Fabian, M., Liebert, A.,... Zaiß, M. (2022). 7 tricks for 7 T CEST: Improving the reproducibility of multipool evaluation provides insights into the effects of age and the early stages of Parkinson's disease. NMR in Biomedicine. https://dx.doi.org/10.1002/nbm.4717
• Pistel, M., Laun, F.B., Bickelhaupt, S., Dada, A., Weiland, E., Niederdränk, T.,... Ohlmeyer, S. (2022). Differentiating Benign and Malignant Breast Lesions in Diffusion Kurtosis MRI: Does the Averaging Procedure Matter? Journal of Magnetic Resonance Imaging. https://dx.doi.org/10.1002/jmri.28150

2021

• Führes, T., Riexinger, A., Loh, M., Martin, J., Wetscherek, A., Kuder, T.A.,... Laun, F.B. (2021). Echo time dependence of biexponential and triexponential intravoxel incoherent motion parameters in the liver. Magnetic Resonance in Medicine. https://dx.doi.org/10.1002/mrm.28996
• Heiß, R., Nagel, A.M., Laun, F.B., Uder, M., & Bickelhaupt, S. (2021). Low-Field Magnetic Resonance Imaging: A New Generation of Breakthrough Technology in Clinical Imaging. Investigative Radiology, 56(11), 726-733. https://dx.doi.org/10.1097/RLI.0000000000000805
• Jia, F., Littin, S., Amrein, P., Yu, H., Magill, A.W., Kuder, T.A.,... Zaitsev, M. (2021). Design of a high-performance non-linear gradient coil for diffusion weighted MRI of the breast. Journal of Magnetic Resonance, 331. https://dx.doi.org/10.1016/j.jmr.2021.107052
• Laun, F.B., Martin, J., Reymbaut, A., Schmidt, M., Dörfler, A., Topgaard, D., & Uder, M. (2021). Nonparametric D-R1-R2 distribution MRI of the living human brain.
• Ludwig, D., Laun, F.B., Ladd, M.E., Bachert, P., & Kuder, T.A. (2021). Apparent exchange rate imaging: On its applicability and the connection to the real exchange rate. Magnetic Resonance in Medicine. https://dx.doi.org/10.1002/mrm.28714
• Mayer, P., Fritz, F., Koell, M., Skornitzke, S., Bergmann, F., Gaida, M.M.,... Stiller, W. (2021). Assessment of tissue perfusion of pancreatic cancer as potential imaging biomarker by means of Intravoxel incoherent motion MRI and CT perfusion: correlation with histological microvessel density as ground truth. Cancer Imaging, 21(1). https://dx.doi.org/10.1186/s40644-021-00382-x
• Ohlmeyer, S., Laun, F.B., Bickelhaupt, S., Palm, T., Janka, R.M., Weiland, E.,... Wenkel, E. (2021). Ultra-High b-Value Diffusion-Weighted Imaging-Based Abbreviated Protocols for Breast Cancer Detection. Investigative Radiology, 56(10), 629-636. https://dx.doi.org/10.1097/RLI.0000000000000784
• Riexinger, A., Laun, F.B., Hoeger, S.A., Wiesmüller, M., Uder, M., Hensel, B.,... Heiß, R. (2021). Effect of compression garments on muscle perfusion in delayed-onset muscle soreness: A quantitative analysis using intravoxel incoherent motion MR perfusion imaging. NMR in Biomedicine. https://dx.doi.org/10.1002/nbm.4487
• Saake, M., Seuß, H., Riexinger, A., Bickelhaupt, S., Hammon, M., Uder, M., & Laun, F.B. (2021). Image Quality and Detection of Small Focal Liver Lesions in Diffusion-Weighted Imaging Comparison of Navigator Tracking and Free-Breathing Acquisition. Investigative Radiology, 56(9), 579-590. https://dx.doi.org/10.1097/RLI.0000000000000776
• Slator, P.J., Palombo, M., Miller, K.L., Westin, C.-F., Laun, F.B., Kim, D.,... Hutter, J. (2021). Combined diffusion-relaxometry microstructure imaging: Current status and future prospects. Magnetic Resonance in Medicine. https://dx.doi.org/10.1002/mrm.28963
• Voelker, M.N., Kraff, O., Goerke, S., Laun, F.B., Hanspach, J., Pine, K.J.,... Quick, H.H. (2021). The traveling heads 2.0: Multicenter reproducibility of quantitative imaging methods at 7 Tesla. NeuroImage, 232. https://dx.doi.org/10.1016/j.neuroimage.2021.117910
• Wiesmüller, M., Wüst, W., May, M., Ellmann, S., Heiß, R., Saake, M.,... Laun, F.B. (2021). Comparison of Readout-Segmented Echo-Planar Imaging and Single-Shot TSE DWI for Cholesteatoma Diagnostics. American Journal of Neuroradiology. https://dx.doi.org/10.3174/ajnr.A7112

2020

• Dreher, C., Kuder, T.A., König, F., Paech, D., Tavakoli, A., Flothow, F.,... Laun, F.B. (2020). Advanced Diffusion-Weighted Abdominal Imaging: Qualitative and Quantitative Comparison of High and Ultra-High b-Values for Lesion Detection and Image Quality. Investigative Radiology, 55(5), 285-292. https://dx.doi.org/10.1097/RLI.0000000000000639
• Hanspach, J., Nagel, A.M., Hensel, B., Uder, M., Koros, L., & Laun, F.B. (2020). Sample size estimation: Current practice and considerations for original investigations in MRI technical development studies. Magnetic Resonance in Medicine. https://dx.doi.org/10.1002/mrm.28550
• Lambrecht, V., Hanspach, J., Hoffmann, A., Seyler, L., Mennecke, A., Straub, S.,... Laun, F.B. (2020). Quantitative susceptibility mapping depicts severe myelin deficit and iron deposition in a transgenic model of multiple system atrophy. Experimental Neurology, 329. https://dx.doi.org/10.1016/j.expneurol.2020.113314
• Mlynarska-Bujny, A., Bickelhaupt, S., Laun, F.B., König, F., Lederer, W., Daniel, H.,... Kuder, T.A. (2020). Influence of residual fat signal on diffusion kurtosis MRI of suspicious mammography findings. Scientific Reports, 10(1). https://dx.doi.org/10.1038/s41598-020-70154-3
• Rauh, S.S., Riexinger, A., Ohlmeyer, S., Hammon, M., Saake, M., Stemmer, A.,... Laun, F.B. (2020). A mixed waveform protocol for reduction of the cardiac motion artifact in black-blood diffusion-weighted imaging of the liver. Magnetic Resonance Imaging, 67, 59-68. https://dx.doi.org/10.1016/j.mri.2019.12.011
• Riexinger, A., Laun, F.B., Bickelhaupt, S., Seuß, H., Uder, M., Hensel, B., & Saake, M. (2020). On the dependence of the cardiac motion artifact on the breathing cycle in liver diffusion-weighted imaging. PLoS ONE, 15(10 October). https://dx.doi.org/10.1371/journal.pone.0239743
• Riexinger, A., Martin, J., Wetscherek, A., Kuder, T.A., Uder, M., Hensel, B., & Laun, F.B. (2020). An optimized b-value distribution for triexponential intravoxel incoherent motion (IVIM) in the liver. Magnetic Resonance in Medicine. https://dx.doi.org/10.1002/mrm.28582
• Wetscherek, A., & Laun, F.B. (2020). Chapter 5: Separating Flow from Diffusion Using Velocity-compensated Diffusion Encoding. In Daniel Topgaard (Eds.), New Developments in NMR. (pp. 123-153). Royal Society of Chemistry.
• Witulla, B., Goerig, N., Putz, F., Frey, B., Engelhorn, T., Dörfler, A.,... Laun, F.B. (2020). On PTV definition for glioblastoma based on fiber tracking of diffusion tensor imaging data. PLoS ONE, 15(1), e0227146-. https://dx.doi.org/10.1371/journal.pone.0227146