We are bridging the gap between data generation in the clinical context and data-driven projects in the scientific context by researching interoperable and FAIR research environments.
Research projects
MIRACUM (BMBF 2017 – 2026) – Medical Informatics in Research and Care in University Medicine
IMMERSE (EU 2021- 2025) – Implementing Mobile MEntal health Recording Strategy for Europe
InterPOLAR (BMBF, 2021-2026) – INTERventional POLypharmacy – drug InterActions – Risks
PrivateAIM (BMBF, 2023-2027) – Privacy-Preserving Analytics in Medicine
CALM-QE (BMBF, 2023-2027) – COPD and asthma: longitudinal and cross-sectoral real-world data for machine learning application for quality improvement and knowledge acquisition
PM4Onco (BMBF, 2023-2027) – Personalized Medicine for Oncology
GeMTeX (BMBF, 2023-2027) – German Medical Text Corpus
OMI (BMBF, 2023-2027) – Open Medical Inference
PCOR-MII (BMBF, 2024-2027) – Patient-Centered Outcomes Research within the Medical Informatics Initiative
Current projects
EMOPROM LCN - Multidisziplinäre Online PROMs im Long-COVID Netzwerk von ambulanten, stationären und rehabilitativen Sektoren in Zusammenarbeit mit Patientinnen und Patienten
(Third Party Funds Single)
Project leader: Yesim Erim , Klaus Überla , Thomas Kühlein , Bettina Hohberger , Thomas Ganslandt , Jürgen Rech , Olaf Gefeller Term: 16. November 2024 - 15. November 2028Acronym: SO-BMG_EMOPROM LCNFunding source: Bundesministerium für Gesundheit (BMG)
Standardisierte Kerndatensätze: AP 2, Patient Journey: AP 3, Visuelle Analytik/Leitung: AP 5, Roll-Out: AP 7, Koordinierung und Öffentlichkeitsarbeit: AP 8
(Third Party Funds Group – Sub project)
Overall project: Medizininformatik-Use Case „Personalized Medicine for OncologyProject leader: Thomas Ganslandt Term: 1. May 2023 - 30. April 2027Acronym: PM4OncoFunding source: Bundesministerium für Forschung, Technologie und Raumfahrt (BMFTR)
DIZ Integration (Leitung) und Roll-out der FLAME Plattform: Universitätsklinikum Erlangen
(Third Party Funds Group – Sub project)
Overall project: Medizininformatik-Plattform "Privatsphären-schützende Analytik in der Medizin"Project leader: Thomas Ganslandt Term: 1. April 2023 - 1. March 2027Acronym: PrivateAIMFunding source: BMBF / Verbundprojekt
INTERPOLAR: WP3 - Interventionelle Studie: Universitätsklinikum Erlangen
(Third Party Funds Group – Sub project)
Overall project: INTERPOLAR - Medizininformatik-Use Case "INTERventional POLypharmacy - drug interActions - Risks"Project leader: Hans-Ulrich Prokosch , Thomas Ganslandt , Frank Dörje Term: 1. January 2023 - 31. December 2026Acronym: INTERPOLARFunding source: BMBF / Verbundprojekt
Recent publications
2025
Kampf, M.O., Prokosch, H.-U., Gulden, C., Kraska, D., Ganslandt, T., & Seuchter, S.A. (2025). Evaluation of a DIC Broad Consent Cohort . In Elisavet Andrikopoulou, Parisis Gallos, Theodoros N. Arvanitis, Rosalynn Austin, Arriel Benis, Ronald Cornet, Panagiotis Chatzistergos, Alexander Dejaco, Linda Dusseljee-Peute, Alaa Mohasseb, Pantelis Natsiavas, Haythem Nakkas, Philip Scott (Eds.), Intelligent Health Systems – From Technology to Data and Knowledge. (pp. 492-496). IOS Press.
Rogge, A.A., Mukowski-Kickhöfel, R., Boeker, M., Budde, K., Debertshäuser, T., Dugas, M.,... Prasser, F. (2025). Integrating the Patient Perspective into Healthcare and Real-World Evidence: The Multi-site, Cross-Disease, Patient-Centered Outcomes Research Project in the Medical Informatics Initiative (PCOR-MII) . Journal of Healthcare Informatics Research . https://doi.org/10.1007/s41666-025-00187-8
Strantz, C., Böhm, D., Ganslandt, T., Börries, M., Metzger, P., Pauli, T.,... Unberath, P. (2025). Empowering personalized oncology: evolution of digital support and visualization tools for molecular tumor boards. BMC Medical Informatics and Decision Making , 25 (1). https://doi.org/10.1186/s12911-024-02821-8
Weidinger, F., Räbel, J., Grässel, E., Ganslandt, T., Kolominsky-Rabas, P., & Emmert, M. (2025). Costs of informal caregiving for people with cognitive impairment: A cost study based on the Digital Dementia Registry Bavaria (digiDEM Bayern) Kosten informeller Pflege bei Menschen mit kognitiven Beeinträchtigungen: eine Kostenstudie aus dem Digitalen Demenzregister Bayern (digiDEM Bayern) . Zeitschrift für Evidenz, Fortbildung und Qualitat im Gesundheitswesen , 198-199 , 27-34. https://doi.org/10.1016/j.zefq.2025.10.001
Ziegler, J., Fischer, C., Volkmer, P.C., Erpenbeck, M.P., Mang, J.M., Ganslandt, T.,... Gulden, C. (2025). Assuring End-to-End Data Quality for Analytics on FHIR . In Martin Baumgartner, Dieter Hayn, Bernhard Pfeifer, Günter Schreier (Eds.), dHealth 2025. (pp. 57-62). IOS Press.
2024
Ammon, D., Kurscheidt, M., Buckow, K., Kirsten, T., Löbe, M., Meineke, F.,... Ganslandt, T. (2024). Arbeitsgruppe Interoperabilität: Kerndatensatz und Informationssysteme für Integration und Austausch von Daten in der Medizininformatik-Initiative . Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz , 67 (6), 656-667. https://doi.org/10.1007/s00103-024-03888-4
Böhm, D., Strantz, C., Christoph, J., Busch, H., Ganslandt, T., & Unberath, P. (2024). Data Visualization Support for Tumor Boards and Clinical Oncology: Protocol for a Scoping Review. JMIR Research Protocols , 13 . https://doi.org/10.2196/53627
Gierend, K., Krüger, F., Genehr, S., Hartmann, F., Siegel, F., Waltemath, D.,... Zeleke, A.A. (2024). Provenance Information for Biomedical Data and Workflows: Scoping Review . Journal of Medical Internet Research , 26 (1). https://doi.org/10.2196/51297
Kapsner, L., Feißt, M., Purbojo, A., Prokosch, H.-U., Ganslandt, T., Dittrich, S.,... Wällisch, W. (2024). Using Machine Learning and Feature Importance to Identify Risk Factors for Mortality in Pediatric Heart Surgery . Diagnostics , 14 (22). https://doi.org/10.3390/diagnostics14222587
Kapsner, L., Folle, L., Hadler, D., Eberle, J., Balbach, E., Liebert, A.,... Bickelhaupt, S. (2024). Lesion-conditioning of synthetic MRI-derived subtraction-MIPs of the breast using a latent diffusion model . Scientific Reports , 14 (1). https://doi.org/10.1038/s41598-024-56853-1
Kleinert, P., Gebhardt, M., Buckow, K., Gründner, J., Ganslandt, T., Prokosch, H.-U., & Semler, S.C. (2024). Germany's Approach for the Secondary Use of Federated Real-World Data in the German Portal for Medical Research Data . In John Mantas, Arie Hasman, George Demiris, Kaija Saranto, Michael Marschollek, Theodoros N. Arvanitis, Ivana Ognjanovic, Arriel Benis, Parisis Gallos, Emmanouil Zoulias, Elisavet Andrikopoulou (Eds.), Studies in Health Technology and Informatics (pp. 1704-1708). Athens, GRC: IOS Press BV.
Michaelis, L., Inau, E.T., Muzoora, M.R., Wodke, J.A., Ganslandt, T., Thun, S., & Waltemath, D. (2024). Applying the RDA Data Maturity Model on the Core Dataset of the German Medical Informatics Initiative . In Marco Roos, Annika Jacobsen, Andrea Splendiani, M. Scott Marshall, Andra Waagmeester, Leyla Jael Garcia Castro, Katherine Wolstencroft, Kristina Hettne, Rutger Vos (Eds.), Proceedings of the 15th International Conference on Semantic Web Applications and Tools for Health Care and Life Sciences (SWAT4HCLS 2024) (pp. 124-128). Hybrid, Leiden, NL: CEUR-WS.
Myin-Germeys, I., Schick, A., Ganslandt, T., Hajdúk, M., Heretik, A., Van Hoyweghen, I.,... Reininghaus, U. (2024). The experience sampling methodology as a digital clinical tool for more person-centered mental health care: an implementation research agenda . Psychological Medicine . https://doi.org/10.1017/S0033291724001454
Schmitt, J., Ihle, P., Schoffer, O., Reese, J.P., Ortmann, S., Swart, E.,... Zeynalova, S. (2024). Datennutzung für eine bessere Gesundheitsversorgung–Plädoyer für eine kooperative Forschungsdatenplattform der gesetzlichen und privaten Krankenversicherung und dem Netzwerk Universitätsmedizin (NUM) . Gesundheitswesen . https://doi.org/10.1055/a-2438-0670
Wabo, G.K., Moorthy, P., Siegel, F., Seuchter, S.A., & Ganslandt, T. (2024). Evaluating and Enhancing the Fitness-for-Purpose of Electronic Health Record Data: Qualitative Study on Current Practices and Pathway to an Automated Approach Within the Medical Informatics for Research and Care in University Medicine Consortium . JMIR Medical Informatics , 12 . https://doi.org/10.2196/57153
2023
Gierend, K., Freiesleben, S., Kadioglu, D., Siegel, F., Ganslandt, T., & Waltemath, D. (2023). The Status of Data Management Practices Across German Medical Data Integration Centers: Mixed Methods Study . Journal of Medical Internet Research , 25 , e48809-. https://doi.org/10.2196/48809
Gierend, K., Waltemath, D., Ganslandt, T., & Siegel, F. (2023). Traceable Research Data Sharing in a German Medical Data Integration Center With FAIR (Findability, Accessibility, Interoperability, and Reusability)-Geared Provenance Implementation: Proof-of-Concept Study . JMIR Formative Research , 7 . https://doi.org/10.2196/50027
Kim, H.E., Maros, M.E., Miethke, T., Kittel, M., Siegel, F., & Ganslandt, T. (2023). Lightweight Visual Transformers Outperform Convolutional Neural Networks for Gram-Stained Image Classification: An Empirical Study . Biomedicines , 11 (5). https://doi.org/10.3390/biomedicines11051333
Wabo, G.K., Prasser, F., Gierend, K., Siegel, F., & Ganslandt, T. (2023). Data Quality– and Utility-Compliant Anonymization of Common Data Model–Harmonized Electronic Health Record Data: Protocol for a Scoping Review . JMIR Research Protocols , 12 . https://doi.org/10.2196/46471
2022
Kim, H.E., Cosa-Linan, A., Santhanam, N., Jannesari, M., Maros, M.E., & Ganslandt, T. (2022). Transfer learning for medical image classification: a literature review . BMC Medical Imaging , 22 (1), 69-. https://doi.org/10.1186/s12880-022-00793-7
Kim, H.E., Maros, M.E., Siegel, F., & Ganslandt, T. (2022). Rapid Convolutional Neural Networks for Gram-Stained Image Classification at Inference Time on Mobile Devices: Empirical Study from Transfer Learning to Optimization . Biomedicines , 10 (11). https://doi.org/10.3390/biomedicines10112808
Löbe, M., Bialke, M., Bienzeisler, J., Drepper, J., Ganslandt, T., Haderer, S.,... Kaulke, K. (2022). ToolPool Gesundheitsforschung - A Repository for Software and Services Focused on Supporting Clinical and Epidemiological Research. Studies in Health Technology and Informatics , 293 , 19-27. https://doi.org/10.3233/SHTI220342
Scheer, J., Volkert, A., Brich, N., Weinert, L., Santhanam, N., Krone, M.,... Nagel, T. (2022). Visualization Techniques of Time-Oriented Data for the Comparison of Single Patients With Multiple Patients or Cohorts: Scoping Review . Journal of Medical Internet Research , 24 (10), e38041-. https://doi.org/10.2196/38041
2021
Barberan-Garcia, A., Cano, I., Bongers, B.C., Seyfried, S., Ganslandt, T., Herrle, F., & Martinez-Palli, G. (2021). Digital Support to Multimodal Community-Based Prehabilitation: Looking for Optimization of Health Value Generation . Frontiers in Oncology , 11 . https://doi.org/10.3389/fonc.2021.662013
Gierend, K., Krueger, F., Waltemath, D., Fuenfgeld, M., Ganslandt, T., & Zeleke, A.A. (2021). Approaches and Criteria for Provenance in Biomedical Data Sets and Workflows: Protocol for a Scoping Review. JMIR Research Protocols , 10 (11). https://doi.org/10.2196/31750
Le, T.T., Gutierrez-Sacristan, A., Son, J., Hong, C., South, A.M., Beaulieu-Jones, B.K.,... Xia, Z. (2021). Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19 . Scientific Reports , 11 (1). https://doi.org/10.1038/s41598-021-99481-9
Maros, M.E., Cho, C.G., Junge, A.G., Kaempgen, B., Saase, V., Siegel, F.,... Wenz, H. (2021). Comparative analysis of machine learning algorithms for computer-assisted reporting based on fully automated cross-lingual RadLex mappings . Scientific Reports , 11 (1). https://doi.org/10.1038/s41598-021-85016-9
Melzer, G., Maiwald, T., Prokosch, H.-U., & Ganslandt, T. (2021). Leveraging Real-World Data for the Selection of Relevant Eligibility Criteria for the Implementation of Electronic Recruitment Support in Clinical Trials . Applied Clinical Informatics , 12 (1), 17-26. https://doi.org/10.1055/s-0040-1721010
Rauschenberg, C., Hirjak, D., Ganslandt, T., Schulte-Strathaus, J.C.C., Schick, A., Meyer-Lindenberg, A., & Reininghaus, U. (2021). Digitale Versorgungsformen zur Personalisierung der stationsäquivalenten Behandlung . Der Nervenarzt . https://doi.org/10.1007/s00115-021-01100-5
Riemann, J.F., Teufel, A., Ganslandt, T., Hann, A., Hildebrandt, H., Jütte, H.,... Hüppe, D. (2021). Digital communication strategies in gastroenterology: Position paper of the LebensBlicke Foundation Digitale Kommunikationsstrategien in der Gastroenterologie . Zeitschrift für Gastroenterologie , 59 (5), 473-474. https://doi.org/10.1055/a-1458-6430
Trinkmann, F., Maros, M., Roth, K., Hermanns, A., Schaefer, J., Gawlitza, J.,... Ganslandt, T. (2021). Multiple breath washout (MBW) testing using sulfur hexafluoride: Reference values and influence of anthropometric parameters . Thorax , 76 (4), 380-386. https://dx.doi.org/10.1136/thoraxjnl-2020-214717
Zimmermann, R., Becker, A., Hackstein, H., & Ganslandt, T. (2021). Generation of Reliable Red Cell Concentrate Requirement Lists for Operations and Interventions from Data Warehouse Data and Patient-Related Batch Documentation of Blood Components . Transfusionsmedizin , 11 (01), 33-37. https://doi.org/10.1055/a-1256-4465
2020
Becker, L., Ganslandt, T., Prokosch, H.-U., & Newe, A. (2020). Applied Practice and Possible Leverage Points for Information Technology Support for Patient Screening in Clinical Trials: Qualitative Study . JMIR Medical Informatics , 8(6) , 1 - 14. https://doi.org/10.2196/15749
Bild, R., Bialke, M., Buckow, K., Ganslandt, T., Ihrig, K., Jahns, R.,... Prasser, F. (2020). Towards a comprehensive and interoperable representation of consent-based data usage permissions in the German medical informatics initiative . BMC Medical Informatics and Decision Making , 20 (1). https://doi.org/10.1186/s12911-020-01138-6
Brat, G.A., Weber, G.M., Gehlenborg, N., Avillach, P., Palmer, N.P., Chiovato, L.,... Kohane, I.S. (2020). International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium . npj Digital Medicine , 3 (1). https://doi.org/10.1038/s41746-020-00308-0
Buergy, D., Siefert, V., Neumaier, C., Ganslandt, T., Sperk, E., Blessing, M.,... Giordano, F.A. (2020). Prospective trial on telemonitoring of geriatric cancer patients using handheld devices . Strahlentherapie und Onkologie , 196 (3), 205-212. https://doi.org/10.1007/s00066-019-01548-0
Ellmann, S., Schlicht, M., Dietzel, M., Janka, R.M., Hammon, M., Saake, M.,... Bäuerle, T. (2020). Computer-aided diagnosis in multiparametric mri of the prostate: An open-access online tool for lesion classification with high accuracy . Cancers , 12 (9), 1-15. https://doi.org/10.3390/cancers12092366
Giordano, F.A., Welzel, G., Siefert, V., Jahnke, L., Ganslandt, T., Wenz, F.,... Nicolay, N.H. (2020). Digital Follow-Up and the Perspective of Patient-Centered Care in Oncology: What's the PROblem? Oncology , 98 (6), 379-385. https://doi.org/10.1159/000495294
Kim, H., Ganslandt, T., Miethke, T., Neumaier, M., & Kittel, M. (2020). Deep learning frameworks for rapid gram stain image data interpretation: Protocol for a retrospective data analysis . JMIR Research Protocols , 9 (7). https://doi.org/10.2196/16843
Schaaf, J., Sedlmayr, M., Prokosch, H.-U., Ganslandt, T., Schade-Brittinger, C., von Wagner, M.,... Storf, H. (2020). The Status Quo of Rare Diseases Centres for the Development of a Clinical Decision Support System - A Cross-Sectional Study . In Günter Schreier, Dieter Hayn, Alphons Eggerth (Eds.), dHealth 2020 – Biomedical Informatics for Health and Care. (pp. 176-183).
Trinkmann, F., Lenz, S.A., Schafer, J., Gawlitza, J., Schroeter, M., Gradinger, T.,... Saur, J. (2020). Feasibility and clinical applications of multiple breath wash-out (MBW) testing using sulphur hexafluoride in adults with bronchial asthma . Scientific Reports , 10 (1). https://doi.org/10.1038/s41598-020-58538-x
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Contact:
We are bridging the gap between data generation in the clinical context and data-driven projects in the scientific context by researching interoperable and FAIR research environments.
Research projects
EMOPROM LCN - Multidisziplinäre Online PROMs im Long-COVID Netzwerk von ambulanten, stationären und rehabilitativen Sektoren in Zusammenarbeit mit Patientinnen und Patienten
(Third Party Funds Single)
Term: 16. November 2024 - 15. November 2028
Acronym: SO-BMG_EMOPROM LCN
Funding source: Bundesministerium für Gesundheit (BMG)
Standardisierte Kerndatensätze: AP 2, Patient Journey: AP 3, Visuelle Analytik/Leitung: AP 5, Roll-Out: AP 7, Koordinierung und Öffentlichkeitsarbeit: AP 8
(Third Party Funds Group – Sub project)
Project leader: Thomas Ganslandt
Term: 1. May 2023 - 30. April 2027
Acronym: PM4Onco
Funding source: Bundesministerium für Forschung, Technologie und Raumfahrt (BMFTR)
DIZ Integration (Leitung) und Roll-out der FLAME Plattform: Universitätsklinikum Erlangen
(Third Party Funds Group – Sub project)
Project leader: Thomas Ganslandt
Term: 1. April 2023 - 1. March 2027
Acronym: PrivateAIM
Funding source: BMBF / Verbundprojekt
INTERPOLAR: WP3 - Interventionelle Studie: Universitätsklinikum Erlangen
(Third Party Funds Group – Sub project)
Project leader: Hans-Ulrich Prokosch, Thomas Ganslandt, Frank Dörje
Term: 1. January 2023 - 31. December 2026
Acronym: INTERPOLAR
Funding source: BMBF / Verbundprojekt
2025
2024
2023
2022
2021
2020
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