In general, we aim to implement novel technologies such as Robotics and brain-computer interfaces to treat a variety of neurological disorders. Furthermore, we steadily investigate innovative operative procedures such as MR-based Functional Neurosurgery using low-field MRI (0.5 T). I have a particular, personal interest in the clinical treatment and study of objective biomarkers/predictive factors of patients with chronic refractory pain syndrome, who are treated using electrical (DBS, SCS, ONS, PENS, VNS) and biochemical (pharmacotherapy) neuromodulation. To date, this is based on subjective patient-specific assessments (headache diary, pain scales). To improve this short-come we assess the clinical value of molecular and digital phenotyping of chronic pain patients treated with neuromodulation therapies.
Research projects
Robotic-assisted Functional Neurosurgery and Stereotaxy
Molecular and digital phenotyping in chronic pain patients under neuromodulation therapies. Cooperation Prof. Rohleder (Psychology/Health Sciences) and Prof Eskofier (Dept. of Machine Learning and Data Analytics)
MR-based Brain Stimulation using low-field (0.5 T) MRI. Cooperation Prof. Uder (Radiology), Siemens and ClearPoint Inc.
A General hybrid interface with human cortical and spinal motoneurons for motor control research in patients with muscle paralysis due to cerebral stroke and/or spinal cord injury. Cooperation Prof. Del Vecchio Chair of Neuromuscular Physiology and Neural Interfacing Department of Artificial Intelligence in Biomedical Engineering, AIBE
Recent publications
2021
Beniczky, S., Asadi-Pooya, A.A., Perucca, E., Rubboli, G., Tartara, E., Meritam Larsen, P.,... Sperling, M.R. (2021). A web-based algorithm to rapidly classify seizures for the purpose of drug selection . Epilepsia . https://dx.doi.org/10.1111/epi.17039
Berkmann, S., Lattmann, J., Schuetz, P., Diepers, M., Remonda, L., Fandino, J.,... Mueller, B. (2021). The Shape grading system: a classification for growth patterns of pituitary adenomas . Acta Neurochirurgica . https://dx.doi.org/10.1007/s00701-021-04912-1
Chaudhry, S.R., Kahlert, U.D., Kinfe, T.M., Endl, E., Dolf, A., Niemela, M.,... Muhammad, S. (2021). Differential polarization and activation dynamics of systemic T helper cell subsets after aneurysmal subarachnoid hemorrhage (SAH) and during post-SAH complications . Scientific Reports , 11 (1). https://dx.doi.org/10.1038/s41598-021-92873-x
Deutschbein, T., Jaursch-Hancke, C., Knappe, U.J., Saeger, W., Flitsch, J., Bojunga, J.,... Fassnacht, M. (2021). First German Guideline on Diagnostics and Therapy of Clinically Non-Functioning Pituitary Tumors . Experimental and Clinical Endocrinology and Diabetes , 129 (3), 250-264. https://dx.doi.org/10.1055/a-1386-9145
Hofmann, A., Fietkau, R., & Distel, L. (2021). Proliferating non-professional Phagocytes to generate Cell-in-Cell Structures . In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S214-S215). HEIDELBERG: SPRINGER HEIDELBERG.
Hore, N., Lücking, H., Schmitt, H., Buchfelder, M., & Brandner, S. (2021). Pedicle screw instrumentation of the cervicothoracic junction in the sitting position using ct-guided navigation: Application and technical aspects . Journal of Neurological Surgery Part A: Central European Neurosurgery . https://dx.doi.org/10.1055/s-0040-1718409
Kinfe, T.M., Buchfelder, M., & Stadlbauer, A. (2021). Can we use the dynamic and complex interplay between pain and sleep to quantify neuromodulation responsiveness for chronic pain? Expert review of neurotherapeutics . https://dx.doi.org/10.1080/14737175.2021.1865805
Marcus, H.J., Khan, D.Z., Borg, A., Buchfelder, M., Cetas, J.S., Collins, J.W.,... Laws, E.R. (2021). Pituitary society expert Delphi consensus: operative workflow in endoscopic transsphenoidal pituitary adenoma resection . Pituitary . https://dx.doi.org/10.1007/s11102-021-01162-3
Marzahl, C., Aubreville, M., Bertram, C.A., Stayt, J., Jasensky, A.K., Bartenschlager, F.,... Maier, A. (2021). Abstract: Deep Learning-based Quantification of Pulmonary Hemosiderophages in Cytology Slides . In Christoph Palm, Heinz Handels, Klaus Maier-Hein, Thomas M. Deserno, Andreas Maier, Thomas Tolxdorff (Eds.), Informatik aktuell (pp. 48-). Regensburg, DE: Springer Science and Business Media Deutschland GmbH.
Ng, S., Messerer, M., Engelhardt, J., Bruneau, M., Cornelius, J.F., Cavallo, L.M.,... Jouanneau, E. (2021). Aggressive pituitary neuroendocrine tumors: current practices, controversies, and perspectives, on behalf of the EANS skull base section . Acta Neurochirurgica . https://dx.doi.org/10.1007/s00701-021-04953-6
Rampp, S., Rössler, K., Hamer, H., Illek, M., Buchfelder, M., Dörfler, A.,... Coras, R. (2021). Dysmorphic neurons as cellular source for phase-amplitude coupling in Focal Cortical Dysplasia Type II . Clinical Neurophysiology , 132 (3), 782-792. https://dx.doi.org/10.1016/j.clinph.2021.01.004
Reincke, M., Albani, A., Assie, G., Bancos, I., Brue, T., Buchfelder, M.,... Ritzel, K. (2021). Corticotroph tumor progression after bilateral adrenalectomy (Nelson's syndrome): systematic review and expert consensus recommendations . European Journal of Endocrinology , 184 (3), P1-P16. https://dx.doi.org/10.1530/EJE-20-1088
Reuß, A.M., Groos, D., Ghoochani, A., Buchfelder, M., & Savaskan, N. (2021). MCT4 Promotes Tumor Malignancy in F98 Glioma Cells . Journal of Oncology , 2021 . https://dx.doi.org/10.1155/2021/6655529
Runge, J., Ascencao, L.C., Blahak, C., Kinfe, T.M., Schrader, C., Wolf, M.E.,... Krauss, J.K. (2021). Deep brain stimulation in patients on chronic antiplatelet or anticoagulation treatment . Acta Neurochirurgica . https://dx.doi.org/10.1007/s00701-021-04931-y
Rössler, K., Kasper, B., Tomschik, M., Dörfler, A., Buchfelder, M., & Dorfer, C. (2021). Neurochirurgische Operationsmöglichkeiten bei posteriorer Epilepsie . Zeitschrift für Epileptologie . https://dx.doi.org/10.1007/s10309-020-00386-w
Shawarba, J., Kaspar, B., Rampp, S., Winter, F., Coras, R., Blümcke, I.,... Roessler, K. (2021). Advantages of magnetoencephalography, neuronavigation and intraoperative MRI in epilepsy surgery re-operations . Neurological Research . https://dx.doi.org/10.1080/01616412.2020.1866384
Stadlbauer, A., Kinfe, T.M., Eyüpoglu, I.Y., Zimmermann, M., Kitzwoegerer, M., Podar, K.,... Marhold, F. (2021). Tissue hypoxia and alterations in microvascular architecture predict glioblastoma recurrence in humans . Clinical Cancer Research , 27 (6), 1641-1649. https://dx.doi.org/10.1158/1078-0432.CCR-20-3580
Stadlbauer, A., Oberndorfer, S., Heinz, G., Zimmermann, M., Kinfe, T.M., Dörfler, A.,... Marhold, F. (2021). Hypoxia and microvascular alterations are early predictors of IDH-mutated anaplastic glioma recurrence . Cancers , 13 (8). https://dx.doi.org/10.3390/cancers13081797
Warmbier, J., Luedecke, D.K., Flitsch, J., Buchfelder, M., Fahlbusch, R., Knappe, U.J.,... Saeger, W. (2021). Typing of inflammatory lesions of the pituitary . Pituitary . https://dx.doi.org/10.1007/s11102-021-01180-1
Wartchow, K.M., Schmid, B., Tripal, P., Stadlbauer, A., Buchfelder, M., Goncalves, C.-A., & Kleindienst, A. (2021). Treatment with Cyclic AMP Activators Reduces Glioblastoma Growth and Invasion as Assessed by Two-Photon Microscopy . Cells , 10 (3). https://dx.doi.org/10.3390/cells10030556
Winter, F., Markert, C., Krawagna, M., Buchfelder, M., & Roessler, K. (2021). Clipping of unruptured cerebral aneurysms: Are older patients at higher risk? Wiener Klinische Wochenschrift . https://dx.doi.org/10.1007/s00508-021-01887-y
Yakubov, E., Eibl, T., Hammer, A., Holtmannspotter, M., Savaskan, N., & Steiner, H.-H. (2021). Therapeutic Potential of Selenium in Glioblastoma . Frontiers in Neuroscience , 15 . https://dx.doi.org/10.3389/fnins.2021.666679
2020
Alvarez-Fischer, D., Vernik, T., Vulinovic, F., Herrmann, A., Westenberger, A., & Klein, C. (2020). Transgenerational transduction of MPTP-induced alterations in a Parkinson's disease mouse model . Parkinsonism & related disorders , 79 , 88-90. https://dx.doi.org/10.1016/j.parkreldis.2020.08.017
Antonakakis, M., Schrader, S., Aydin, Ü., Khan, A., Gross, J., Zervakis, M.,... Wolters, C.H. (2020). Inter-Subject Variability of Skull Conductivity and Thickness in Calibrated Realistic Head Models . NeuroImage , 223 . https://dx.doi.org/10.1016/j.neuroimage.2020.117353
Asadi-Pooya, A.A., Beniczky, S., Rubboli, G., Sperling, M.R., Rampp, S., & Perucca, E. (2020). A pragmatic algorithm to select appropriate antiseizure medications in patients with epilepsy . Epilepsia . https://dx.doi.org/10.1111/epi.16610
Bagić, A.I., & Rampp, S. (2020). It is time to harmonize clinical MEG practice internationally . Clinical Neurophysiology , 131 (8), 1769-1771. https://dx.doi.org/10.1016/j.clinph.2020.04.020
Barany, L., Meszaros, C., Ganslandt, O., Buchfelder, M., & Kurucz, P. (2020). Neural and vascular architecture of the septum pellucidum: an anatomical study and considerations for safe endoscopic septum pellucidotomy . Journal of Neurosurgery , 133 (3), 902-911. https://dx.doi.org/10.3171/2019.5.JNS19754
Bayer, S., Spiske, U., Geimer, T., Luo, J., Wells III, W.M., Ostermeier, M.,... Maier, A. (2020). An Investigation of Feature-based Nonrigid Image Registration using Gaussian Process . In Springer (Eds.), Algorithmen – Systeme – Anwendungen. Proceedings des Workshops . Berlin: Springer.
Beniczky, S., Blümcke, I., Rampp, S., Shisler, P., Biesel, E., & Wiebe, S. (2020). e-learning comes of age: Web-based education provided by the International League Against Epilepsy . Epileptic Disorders , 22 (3), 237-244. https://dx.doi.org/10.1684/epd.2020.1157
Beniczky, S., Rampp, S., Asadi-Pooya, A.A., Rubboli, G., Perucca, E., & Sperling, M.R. (2020). Optimal choice of antiseizure medication: Agreement among experts and validation of a web-based decision support application . Epilepsia . https://dx.doi.org/10.1111/epi.16763
Bennani-Baiti, B., Pinker, K., Zimmermann, M., Helbich, T.H., Baltzer, P.A., Clauser, P.,... Stadlbauer, A. (2020). Non-invasive assessment of hypoxia and neovascularization with MRI for identification of aggressive breast cancer . Cancers , 12 (8), 1-14. https://dx.doi.org/10.3390/cancers12082024
Buchfelder, M. (2020). Foreword II . In Emmanuel Jouanneau, Gérald Raverot (Eds.), Adult Craniopharyngiomas: Differences and Lessons from Paediatrics. (pp. vii-viii). Springer International Publishing.
Buchfelder, M., & Schlaffer, S.-M. (2020). Surgical treatment of aggressive pituitary adenomas and pituitary carcinomas . Reviews in Endocrine & Metabolic Disorders . https://dx.doi.org/10.1007/s11154-020-09563-8
Chaudhry, S.R., Kahlert, U.D., Kinfe, T.M., Lamprecht, A., Niemelä, M., Hänggi, D., & Muhammad, S. (2020). Elevated systemic Il-10 levels indicate immunodepression leading to nosocomial infections after aneurysmal subarachnoid hemorrhage (SAH) in patients . International Journal of Molecular Sciences , 21 (5). https://dx.doi.org/10.3390/ijms21051569
Chaudhry, S.R., Kinfe, T.M., Lamprecht, A., Niemelä, M., Dobreva, G., Hänggi, D., & Muhammad, S. (2020). Elevated level of cerebrospinal fluid and systemic chemokine CCL5 is a predictive biomarker of clinical outcome after aneurysmal subarachnoid hemorrhage (aSAH) . Cytokine , 133 . https://dx.doi.org/10.1016/j.cyto.2020.155142
Dorfer, C., Rydenhag, B., Baltuch, G., Buch, V., Blount, J., Bollo, R.,... Cukiert, A. (2020). How technology is driving the landscape of epilepsy surgery . Epilepsia . https://dx.doi.org/10.1111/epi.16489
Eisenhut, F., Schmidt, M., Putz, F., Lettmaier, S., Fröhlich, K., Arinrad, S.,... Dörfler, A. (2020). Classification of primary cerebral lymphoma and glioblastoma featuring dynamic susceptibility contrast and apparent diffusion coefficient . Brain Sciences , 10 (11), 1-10. https://dx.doi.org/10.3390/brainsci10110886
Elbelt, U., Schlaffer, S.-M., Buchfelder, M., Knappe, U.J., Vila, G., Micko, A.,... Honegger, J. (2020). Efficacy of Temozolomide Therapy in Patients With Aggressive Pituitary Adenomas and Carcinomas -A German Survey . Journal of Clinical Endocrinology and Metabolism , 105 (3). https://dx.doi.org/10.1210/clinem/dgz211
Federico, P., Ng, D.W., Bernasconi, A., Bernhardt, B., Blumenfeld, H., Cendes, F.,... Wang, I. (2020). ILAE Neuroimaging Task Force highlight: Review MRI scans with semiology in mind . Epileptic Disorders , 22 (5), 683-687. https://dx.doi.org/10.1684/epd.2020.1202
Fiss, I., Röhrig, P., Hore, N., von der Brelie, C., Bettag, C., Freimann, F.B.,... Brandner, S. (2020). In vitro performance of six combinations of adjustable differential pressure valves and fixed anti-siphon devices with and without vertical motion . Acta Neurochirurgica . https://dx.doi.org/10.1007/s00701-020-04519-y
Fiss, I., Vanderheyden, M., von der Brelie, C., Bettag, C., Hore, N., Freimann, F.,... Brandner, S. (2020). In vitro performance of combinations of anti-siphon devices with differential pressure valves in relation to the spatial position . Acta Neurochirurgica . https://dx.doi.org/10.1007/s00701-020-04228-6
Fleseriu, M., Buchfelder, M., Cetas, J.S., Fazeli, P.K., Mallea-Gil, S.M., Gurnell, M.,... Marcus, H.J. (2020). Pituitary society guidance: pituitary disease management and patient care recommendations during the COVID-19 pandemic—an international perspective . Pituitary . https://dx.doi.org/10.1007/s11102-020-01059-7
Gerner, S., Hülsbrink, R., Reichl, J., Mrochen, A., Eyüpoglu, I.Y., Brandner, S.,... Huttner, H. (2020). Parenchymatous hematoma in patients with atraumatic subarachnoid hemorrhage: Characteristics, treatment, and clinical outcomes . International Journal of Stroke . https://dx.doi.org/10.1177/1747493020971878
Gerner, S., Reichl, J., Custal, C., Brandner, S., Eyüpoglu, I.Y., Lücking, H.,... Huttner, H. (2020). Long-Term Complications and Influence on Outcome in Patients Surviving Spontaneous Subarachnoid Hemorrhage . Cerebrovascular Diseases , 49 (3), 307-315. https://dx.doi.org/10.1159/000508577
Giustina, A., Barkhoudarian, G., Beckers, A., Ben-Shlomo, A., Biermasz, N., Biller, B.,... Melmed, S. (2020). Multidisciplinary management of acromegaly: A consensus . Reviews in Endocrine & Metabolic Disorders . https://dx.doi.org/10.1007/s11154-020-09588-z
Goerig, N., Frey, B., Korn, K., Fleckenstein, B., Überla, K., Schmidt, M.,... Fietkau, R. (2020). Early Mortality of Brain Cancer Patients and its Connection to Cytomegalovirus Reactivation During Radiochemotherapy . Clinical Cancer Research , 26 (13), 3259-3270. https://dx.doi.org/10.1158/1078-0432.CCR-19-3195
Graillon, T., Regis, J., Barlier, A., Brue, T., Dufour, H., & Buchfelder, M. (2020). Parasellar Meningiomas . Neuroendocrinology , 110 (9-10), 780-796. https://dx.doi.org/10.1159/000509090
Hanna, J., Kim, C., & Müller-Voggel, N. (2020). External noise removed from magnetoencephalographic signal using independent component analyses of reference channels . Journal of Neuroscience Methods , 335 . https://dx.doi.org/10.1016/j.jneumeth.2020.108592
Hofmann, A., Seeberg, J., Fietkau, R., & Distel, L. (2020). Non-professional Phagocytes can phagocytize Necrotic Cells at any Stage of the Cell Cycle . In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S200-S200). Weisbaden, DE: HEIDELBERG: SPRINGER HEIDELBERG.
Kinfe, T.M., Stadlbauer, A., Bozhkov, Y., Kremenevski, N., Brandner, S., Buchfelder, M., & Chaudhry, S.R. (2020). The Diagnostic and Therapeutic Role of Leptin and Its Receptor ObR in Glioblastoma Multiforme . Cancers , 12 (12). https://dx.doi.org/10.3390/cancers12123691
Kinfe, T.M., Stadlbauer, A., Winder, K., Hurlemann, R., & Buchfelder, M. (2020). Incisionless MR-guided focused ultrasound: technical considerations and current therapeutic approaches in psychiatric disorders . Expert review of neurotherapeutics . https://dx.doi.org/10.1080/14737175.2020.1779590
Kinfe, T.M., von Willebrand, N., Stadlbauer, A., Buchfelder, M., Yearwood, T.L., Muhammad, S.,... Magerl, W. (2020). Quantitative sensory phenotyping in chronic neuropathic pain patients treated with unilateral L4-dorsal root ganglion stimulation . Journal of Translational Medicine , 18 (1). https://dx.doi.org/10.1186/s12967-020-02566-8
Kleindienst, A., Engelhorn, T., Röckelein, V., & Buchfelder, M. (2020). Development of pre-syrinx state and syringomyelia following a minor injury: a case report . Journal of Medical Case Reports , 14 (1). https://dx.doi.org/10.1186/s13256-020-02568-6
Kleindienst, A., Georgiev, S., Schlaffer, S.-M., & Buchfelder, M. (2020). Tolvaptan Versus Fluid Restriction in the Treatment of Hyponatremia Resulting from SIADH Following Pituitary Surgery . Journal of the Endocrine Society , 4 (7). https://dx.doi.org/10.1210/jendso/bvaa068
Kleindienst, A., Laut, F.M., Roeckelein, V., Buchfelder, M., & Dodoo-Schittko, F. (2020). Treatment of posttraumatic syringomyelia: evidence from a systematic review . Acta Neurochirurgica . https://dx.doi.org/10.1007/s00701-020-04529-w
Kobow, K., Jabari, S., Pieper, T., Kudernatsch, M., Polster, T., Woermann, F.G.,... Von Deimling, A. (2020). Mosaic trisomy of chromosome 1q in human brain tissue associates with unilateral polymicrogyria, very early-onset focal epilepsy, and severe developmental delay . Acta Neuropathologica . https://dx.doi.org/10.1007/s00401-020-02228-5
Kremenevski, N., Schlaffer, S.-M., Coras, R., Kinfe, T.M., Graillon, T., & Buchfelder, M. (2020). Skull Base Chordomas and Chondrosarcomas . Neuroendocrinology , 110 (9-10), 836-847. https://dx.doi.org/10.1159/000509386
Kural, M.A., Duez, L., Sejer Hansen, V., Larsson, P.G., Rampp, S., Schulz, R.,... Beniczky, S. (2020). Criteria for defining interictal epileptiform discharges in EEG: A clinical validation study . Neurology , 94 (20), E2139-E2147. https://dx.doi.org/10.1212/WNL.0000000000009439
Kural, M.A., Tankisi, H., Duez, L., Sejer Hansen, V., Udupi, A., Wennberg, R.,... Beniczky, S. (2020). Optimized set of criteria for defining interictal epileptiform EEG discharges . Clinical Neurophysiology , 131 (9), 2250-2254. https://dx.doi.org/10.1016/j.clinph.2020.06.026
Kurucz, P., Meszaros, C., Ganslandt, O., Buchfelder, M., & Barany, L. (2020). The “Valva Cerebri”: Morphometry, Topographic Anatomy and Histology of the Rhomboid Membrane at the Craniocervical Junction . Clinical Anatomy , 33 (1), 56-65. https://dx.doi.org/10.1002/ca.23460
Lindemann, J., Rakers, C., Matuskova, H., Simon, B.J., Kinfe, T.M., & Petzold, G.C. (2020). Vagus nerve stimulation reduces spreading depolarization burden and cortical infarct volume in a rat model of stroke . PLoS ONE , 15 (7), e0236444-. https://dx.doi.org/10.1371/journal.pone.0236444
Lucia, K., Wu, Y., Garcia, J.M., Barlier, A., Buchfelder, M., Saeger, W.,... Theodoropoulou, M. (2020). Hypoxia and the hypoxia inducible factor 1α activate protein kinase A by repressing RII beta subunit transcription . Oncogene . https://dx.doi.org/10.1038/s41388-020-1223-6
Lücking, H., Struffert, T., Gölitz, P., Engelhorn, T., Brandner, S., Kuramatsu, J.,... Dörfler, A. (2020). Stent-Assisted Coiling Using Leo+ Baby Stent: Immediate and Mid-Term Results . Clinical Neuroradiology . https://dx.doi.org/10.1007/s00062-020-00904-3
Manava, P., Naraghi, R., Schmieder, R., Fahlbusch, R., Dörfler, A., Lell, M.M.,... Hastreiter, P. (2020). 3D-Visualization of Neurovascular Compression at the Ventrolateral Medulla in Patients with Arterial Hypertension . Clinical Neuroradiology . https://dx.doi.org/10.1007/s00062-020-00916-z
Marzahl, C., Aubreville, M., Bertram, C.A., Stayt, J., Jasensky, A.K., Bartenschlager, F.,... Maier, A. (2020). Deep Learning-Based Quantification of Pulmonary Hemosiderophages in Cytology Slides . Scientific Reports , 10 (1). https://dx.doi.org/10.1038/s41598-020-65958-2
Miyata, H., Kuwashige, H., Coras, R., Blümcke, I., Rossler, K., Kubota, Y., & Hori, T. (2020). Histopathological Features of Focal Cortical Dysplasia Type IIIc adjacent to Epilepsy-associated Vascular Malformations . In JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (pp. 676-677). ONLINE: CARY: OXFORD UNIV PRESS INC.
Müller, D., Stoll, C., Palumbo-Zerr, K., Böhm, C., Krishnacoumar, B., Ipseiz, N.,... Krönke, G. (2020). PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass . Scientific Reports , 10 (1). https://dx.doi.org/10.1038/s41598-020-65305-5
Nuessel, M., Hamperl, M., Maslarova, A., Chaudhry, S.R., Kohn, J., Stadlbauer, A.,... Kinfe, T.M. (2020). Burst Motor Cortex Stimulation Evokes Sustained Suppression of Thalamic Stroke Pain: A Narrative Review and Single-Case Overview . Pain and Therapy . https://dx.doi.org/10.1007/s40122-020-00221-0
Rampp, S., Kakisaka, Y., Shibata, S., Wu, X., Rössler, K., Buchfelder, M., & Burgess, R.C. (2020). Normal Variants in Magnetoencephalography . Journal of Clinical Neurophysiology , 37 (6), 518-536. https://dx.doi.org/10.1097/WNP.0000000000000484
Ricklefs, F.L., Fita, K.D., Rotermund, R., Piffko, A., Schmid, S., Capper, D.,... Flitsch, J. (2020). Genome-wide DNA methylation profiles distinguish silent from non-silent ACTH adenomas . Acta Neuropathologica . https://dx.doi.org/10.1007/s00401-020-02149-3
Saryyeva, A., Capelle, H.-H., Kinfe, T.M., Schrader, C., & Krauss, J.K. (2020). Pallidal Deep Brain Stimulation in Patients with Prior Bilateral Pallidotomy and Selective Peripheral Denervation for Treatment of Dystonia . Stereotactic and Functional Neurosurgery , 1-5. https://dx.doi.org/10.1159/000509822
Scheller, C., Rampp, S., Tatagiba, M., Gharabaghi, A., Ramina, K.F., Ganslandt, O.,... Strauss, C. (2020). A critical comparison between the semisitting and the supine positioning in vestibular schwannoma surgery: Subgroup analysis of a randomized, multicenter trial . Journal of Neurosurgery , 133 (1), 249-256. https://dx.doi.org/10.3171/2019.1.JNS181784
Schilling, A., Tomasello, R., Henningsen-Schomers, M.R., Zankl, A., Surendra, K., Haller, M.,... Krauß, P. (2020). Analysis of continuous neuronal activity evoked by natural speech with computational corpus linguistics methods . Language, Cognition and Neuroscience . https://dx.doi.org/10.1080/23273798.2020.1803375
Schrader, S., Antonakakis, M., Rampp, S., Engwer, C., & Wolters, C.H. (2020). A novel method for calibrating head models to account for variability in conductivity and its evaluation in a sphere model . Physics in Medicine and Biology , 65 (24). https://dx.doi.org/10.1088/1361-6560/abc5aa
Stadlbauer, A., Kinfe, T.M., Zimmermann, M., Eyüpoglu, I.Y., Brandner, N., Buchfelder, M.,... Brandner, S. (2020). Association between tissue hypoxia, perfusion restrictions, and microvascular architecture alterations with lesion-induced impairment of neurovascular coupling . Journal of Cerebral Blood Flow and Metabolism . https://dx.doi.org/10.1177/0271678X20947546
Stadlbauer, A., Oberndorfer, S., Zimmermann, M., Renner, B., Buchfelder, M., Heinz, G.,... Roessler, K. (2020). Physiologic MR imaging of the tumor microenvironment revealed switching of metabolic phenotype upon recurrence of glioblastoma in humans . Journal of Cerebral Blood Flow and Metabolism , 40 (3), 528-538. https://dx.doi.org/10.1177/0271678X19827885
Wang, I., Bernasconi, A., Bernhardt, B., Blumenfeld, H., Cendes, F., Chinvarun, Y.,... Federico, P. (2020). MRI essentials in epileptology: a review from the ILAE Imaging Taskforce . Epileptic Disorders , 22 (4), 421-437. https://dx.doi.org/10.1684/epd.2020.1174
Winter, F., Blair, L., Buchfelder, M., & Roessler, K. (2020). Application of functional imaging, neuronavigation, and intraoperative MR imaging in the surgical treatment of brain cavernomas . Neurological Research . https://dx.doi.org/10.1080/01616412.2020.1849522
Winter, F., Blair, L., Buchfelder, M., & Roessler, K. (2020). Risk Factors for Poor Postoperative Outcome and Epileptic Symptoms in Patients Diagnosed with Cerebral Cavernous Malformations . Journal of Neurological Surgery Part A: Central European Neurosurgery . https://dx.doi.org/10.1055/s-0040-1715496
Zimmermann, M., Rössler, K., Kaltenhäuser, M., Grummich, P., Yang, B., Buchfelder, M.,... Stadlbauer, A. (2020). Refined Functional Magnetic Resonance Imaging and Magnetoencephalography Mapping Reveals Reorganization in Language-Relevant Areas of Lesioned Brains . World Neurosurgery . https://dx.doi.org/10.1016/j.wneu.2019.10.014
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In general, we aim to implement novel technologies such as Robotics and brain-computer interfaces to treat a variety of neurological disorders. Furthermore, we steadily investigate innovative operative procedures such as MR-based Functional Neurosurgery using low-field MRI (0.5 T). I have a particular, personal interest in the clinical treatment and study of objective biomarkers/predictive factors of patients with chronic refractory pain syndrome, who are treated using electrical (DBS, SCS, ONS, PENS, VNS) and biochemical (pharmacotherapy) neuromodulation. To date, this is based on subjective patient-specific assessments (headache diary, pain scales). To improve this short-come we assess the clinical value of molecular and digital phenotyping of chronic pain patients treated with neuromodulation therapies.
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2021
2020
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