Prof. Dr. Christoph Alexiou

2022

• Friedrich, B., Lyer, S., Janko, C., Unterweger, H., Brox, R., Cunningham, S.,... Tietze, R. (2022). Scavenging of bacteria or bacterial products by magnetic particles functionalized with a broad-spectrum pathogen recognition receptor motif offers diagnostic and therapeutic applications. Acta Biomaterialia, 141, 418-428. https://dx.doi.org/10.1016/j.actbio.2022.01.001
• Friedrich, R.P., Kappes, M., Cicha, I., Tietze, R., Braun, C., Schneider-Stock, R.,... Janko, C. (2022). Optical Microscopy Systems for the Detection of Unlabeled Nanoparticles. International Journal of Nanomedicine, Volume 17, 2139-2163. https://dx.doi.org/10.2147/IJN.S355007
• Xu, H., Reshetnikov, V., Wondrak, M., Eckhardt, L., Kunz-Schughart, L.A., Janko, C.,... Mokhir, A. (2022). Intracellular amplifiers of reactive oxygen species affecting mitochondria as radiosensitizers. Cancers, 14(1). https://dx.doi.org/10.3390/cancers14010208

2021

• Balk, M., Haus, T., Band, J., Unterweger, H., Schreiber, E., Friedrich, R.P.,... Gostian, A.O. (2021). Cellular spion uptake and toxicity in various head and neck cancer cell lines. Nanomaterials, 11(3), 1-19. https://dx.doi.org/10.3390/nano11030726
• Blumler, P., Friedrich, R.P., Pereira, J., Baun, O., Alexiou, C., & Mailander, V. (2021). Contactless Nanoparticle-Based Guiding of Cells by Controllable Magnetic Fields. Nanotechnology, Science and Applications, 14, 91-100. https://dx.doi.org/10.2147/NSA.S298003
• Cicha, I., & Alexiou, C. (2021). Cardiovascular applications of magnetic particles. Journal of Magnetism and Magnetic Materials, 518. https://dx.doi.org/10.1016/j.jmmm.2020.167428
• Friedrich, B., Auger, J.-P., Dutz, S., Cicha, I., Schreiber, E., Band, J.,... Tietze, R. (2021). Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release. International Journal of Molecular Sciences, 22(8). https://dx.doi.org/10.3390/ijms22084143
• Friedrich, R.P., Janko, C., Unterweger, H., Lyer, S., & Alexiou, C. (2021). SPIONs and magnetic hybrid materials: Synthesis, toxicology and biomedical applications. Physical Sciences Review. https://dx.doi.org/10.1515/psr-2019-0093
• Genc, H., Hazur, J., Karakaya, E., Dietel, B., Bider, F., Groll, J.,... Cicha, I. (2021). Differential responses to bioink‐induced oxidative stress in endothelial cells and fibroblasts. International Journal of Molecular Sciences, 22(5), 1-21. https://dx.doi.org/10.3390/ijms22052358
• Gresing, L.J., Radon, P., Friedrich, R.P., Zahn, D., Raasch, M., Mosig, A.S.,... Clement, J.H. (2021). Negatively charged magnetic nanoparticles pass the blood-placenta barrier under continuous flow conditions in a time-dependent manner. Journal of Magnetism and Magnetic Materials, 521. https://dx.doi.org/10.1016/j.jmmm.2020.167535
• Janko, C., Friedrich, R.P., Cicha, I., Unterweger, H., Lyer, S., & Alexiou, C. (2021). Modulation of immune responses by nanoparticles. Nanomedicine. https://dx.doi.org/10.2217/nnm-2021-0198
• Lyer, S., Janko, C., Friedrich, R.P., Cicha, I., Tietze, R., Unterweger, H., & Alexiou, C. (2021). Nanomedicine for vaccination and diagnosis of diseases. Nanomedicine, 16(3), 165-169. https://dx.doi.org/10.2217/nnm-2020-0483
• Sarcletti, M., Park, H., Wirth, J., Englisch, S., Eigen, A., Drobek, D.,... Halik, M. (2021). The remediation of nano-/microplastics from water. Materials Today. https://dx.doi.org/10.1016/j.mattod.2021.02.020
• Wicke, W., Unterweger, H., Kirchner, J., Brand, L., Ahmadzadeh, A., Ahmed, D.,... Schober, R. (2021). Experimental System for Molecular Communication in Pipe Flow With Magnetic Nanoparticles. IEEE Transactions on Molecular, Biological and Multi-Scale Communications. https://dx.doi.org/10.1109/TMBMC.2021.3099399
• Xu, H., Schikora, M., Sisa, M., Daum, S., Klemt, I., Janko, C.,... Mokhir, A. (2021). An Endoplasmic Reticulum Specific Pro-amplifier of Reactive Oxygen Species in Cancer Cells. Angewandte Chemie International Edition. https://dx.doi.org/10.1002/anie.202100054

2020

• Bartunik, M., Unterweger, H., Alexiou, C., Schober, R., Lübke, M., Fischer, G., & Kirchner, J. (2020). Comparative Evaluation of a New Sensor for Superparamagnetic Iron Oxide Nanoparticles in a Molecular Communication Setting. In Springer International Publishing (Eds.), Proceedings of the EAI BICT 2020 - 12th EAI International Conference on Bio-inspired Information and Communications Technologies (pp. 303-316). Online.
• Corek, E., Rodgers, G., Siegrist, S., Einfalt, T., Detampel, P., Schleputz, C.M.,... Huwyler, J. (2020). Shedding Light on Metal-Based Nanoparticles in Zebrafish by Computed Tomography with Micrometer Resolution. Small, e2000746-. https://dx.doi.org/10.1002/smll.202000746
• Fadeel, B., & Alexiou, C. (2020). Brave new world revisited: Focus on nanomedicine. Biochemical and Biophysical Research Communications. https://dx.doi.org/10.1016/j.bbrc.2020.08.046
• Friedrich, R.P., Schreiber, E., Tietze, R., Yang, H., Pilarsky, C., & Alexiou, C. (2020). Intracellular Quantification and Localization of Label-Free Iron Oxide Nanoparticles by Holotomographic Microscopy. Nanotechnology, Science and Applications, 13, 119-130. https://dx.doi.org/10.2147/NSA.S282204
• Gräfe, C., Müller, E.K., Gresing, L., Weidner, A., Radon, P., Friedrich, R.P.,... Clement, J.H. (2020). Magnetic hybrid materials interact with biological matrices. Physical Sciences Review. https://dx.doi.org/10.1515/psr-2019-0114
• Lenz, T., Nicol, P., Castellanos, M.I., Engel, L.C., Lahmann, A.L., Alexiou, C., & Joner, M. (2020). Small dimension–Big impact! Nanoparticle-enhanced non-invasive and intravascular molecular imaging of atherosclerosis in vivo. Molecules, 25(5). https://dx.doi.org/10.3390/molecules25051029
• Mühlberger, M., Unterweger, H., Band, J., Lehmann, C., Heger, L., Dudziak, D.,... Janko, C. (2020). Loading of Primary Human T Lymphocytes with Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Does Not Impair Their Activation after Polyclonal Stimulation. Cells, 9(2). https://dx.doi.org/10.3390/cells9020342
• Nguyen, K., Nuß, B., Mühlberger, M., Unterweger, H., Friedrich, R.P., Alexiou, C., & Janko, C. (2020). Superparamagnetic iron oxide nanoparticles carrying chemotherapeutics improve drug efficacy in monolayer and spheroid cell culture by enabling active accumulation. Nanomaterials, 10(8), 1-21. https://dx.doi.org/10.3390/nano10081577
• Podolska, M., Barras, A., Alexiou, C., Frey, B., Gaipl, U., Boukherroub, R.,... Munoz, L.E. (2020). Graphene Oxide Nanosheets for Localized Hyperthermia-Physicochemical Characterization, Biocompatibility, and Induction of Tumor Cell Death. Cells, 9(3). https://dx.doi.org/10.3390/cells9030776
• Ratschker, T., Egenberger, L., Alev, M., Zschiesche, L., Band, J., Schreiber, E.,... Janko, C. (2020). Mitoxantrone-loaded nanoparticles for magnetically controlled tumor therapy–induction of tumor cell death, release of danger signals and activation of immune cells. Pharmaceutics, 12(10), 1-19. https://dx.doi.org/10.3390/pharmaceutics12100923
• Reshetnikov, V., Özkan, H., Daum, S., Janko, C., Alexiou, C., Sauer, C.,... Mokhir, A. (2020). N-Alkylaminoferrocene-Based Prodrugs Targeting Mitochondria of Cancer Cells. Molecules, 25(11). https://dx.doi.org/10.3390/molecules25112545
• Schapher, M., Koch, M., Weidner, D., Scholz, M., Wirtz, S., Mahajan, A.,... Herrmann, M. (2020). Neutrophil Extracellular Traps Promote the Development and Growth of Human Salivary Stones. Cells, 9(9). https://dx.doi.org/10.3390/cells9092139
• Singh, R., Eitler, D., Morelle, R., Friedrich, R.P., Dietel, B., Alexiou, C.,... Cicha, I. (2020). Optimization of cell seeding on electrospun PCL-silk fibroin scaffolds. European Polymer Journal, 134. https://dx.doi.org/10.1016/j.eurpolymj.2020.109838
• Stein, R., Friedrich, B., Mühlberger, M., Cebulla, N., Schreiber, E., Tietze, R.,... Unterweger, H. (2020). Synthesis and characterization of citrate-stabilized gold-coated superparamagnetic iron oxide nanoparticles for biomedical applications. Molecules, 25(19). https://dx.doi.org/10.3390/molecules25194425
• Zeh, G., Haines, P., Miehlich, M., Kienz, T., Neidlinger, A., Friedrich, R.P.,... Mokhir, A. (2020). Anticancer Effect of an Electronically Coupled Oligoferrocene. Organometallics. https://dx.doi.org/10.1021/acs.organomet.0c00306